Abstract: Provided herein are T-cell receptor (TCR) fusion proteins (TFPs). T-cells engineered to express one or more TFPs. and methods of use thereof for the treatment of diseases, including cancer.

Abstract: Methods, systems, and storage media for determining the similarities of post content for mapping into a hyperspace. In an exemplary method, the disclosure comprises receiving a query at the processor. The method includes determining post data associated with the query. The post data comprises a plurality of posts provided to a social media platform by various users of the platform. The method includes determining, by the processor, a relationship between at least two posts of the plurality of posts. The method includes training, by the processor, a machine language model. The machine language model is based on the query and the relationship between the at least two posts. The method also generates a hyperspace based on the relationship between the at least two posts and the query.

Abstract: A piece of equipment for on-demand food preparation, for instance on an assembly line, that can use an end-of-arm tool to retrieve and deposit food items on a horizontal surface, such as the surface of a conveyor. The end-of-arm tool may include a peel, in which the peel can be translated from a retracted position to an extended position to transfer food items. The piece of equipment may translate the peel quickly into the extended position to facilitate the retrieval of food items from the horizontal surface. The piece of equipment may be rotated to position the robotic appendage and the peel in a desired direction. The peel may include a push bar that may be movable between a withdrawn position and a push position to selectively push items off of the peel.

Abstract: Optical interconnect topologies may be provided using microLEDs. The topologies may interconnect ICs. The optical interconnect topologies may be used in some instances in place of electrical busses.

Abstract: Metabolic engineering has developed microbial cell factories as sustainable alternatives to chemical synthesis from petroleum feedstocks or harvesting of animals and plants, but current methods can be a costly and labor-intensive commitment. Methods are described herein for microfluidic methods of screening thousands of variant cells in order to reduce time and uncertainty to provide improved strains.

Abstract: In some embodiments, a computer-implemented method comprises: using a client application executing on a user device, generating a user interface configured to display one or more search keywords that are associated with a product that a user is viewing on a screen of the user device; displaying the user interface on the user device to depict graphical representations of the one or more search keywords; determining, by the client application, whether a particular search keyword was selected from the one or more search keywords displayed on the user device; in response: determining whether an object GTIF product-token, associated with the particular search keyword, matches a particular pair of a set of GTIF product-token pairs; in response to determining that the object GTIF product-token matches the particular pair, determining particular additional content based on the particular pair, and displaying the particular additional content on the user device.

Abstract: Dynamic memory area configuration includes designating a portion of memory as a specialized memory unit, and reserving a first portion of specialized memory unit for a plurality of page frame table entries (PFTEs) representing a plurality of frames in the specialized memory. One or more of the PFTEs are stored in respective queue entries within a queue in a reserved area of the specialized memory unit. A particular queue entry indicates that a particular PFTE associated with a particular frame is available for use. An offline request to take a second portion of the specialized memory unit offline is received. Whether to fulfill the offline request is determined based on whether the second portion of the specialized memory unit has an associated queue entry within the queue indicating that the associated frame is not in use back a portion of a page frame table (PFT) or the specialized memory unit.

Abstract: A low-emissivity roofing underlayment comprises a woven reinforcing substrate sandwiched between an aluminized bottom layer and a slip resistant top layer. The bottom, aluminized layer is adapted to be placed against the roof sheathing, facing inward toward the roof rafters, and the slip resistant top layer faces outward and may be walked on by roof shingle installers with a decreased risk of slip and fall accidents, thus permitting safer walking during construction of steeper roofs.

Abstract: Methods and systems for performing measurements of stacked semiconductor structures, e.g., stacked memory and logic structures, based on X-Ray transmission scatterometry measurement data are described herein. In some examples, the scattering response of logic structures is modelled directly in signal space by a mathematical expression including a relatively small number of weighted basis functions. The scattering response of the logic structures and the scattering response of the memory structures determined by an electromagnetic response model are combined, e.g., by summation or convolution. The combined modelled signals are compared to the measured signals at the detector to generate an error signal. The error signal is employed to drive a regression analysis employed to optimize parameter values characterizing the memory structures, values of the weighting coefficients of the signal space model, or both. In other examples, the scattering response of the logic structures is known, and a model is not needed.

Abstract: The present application describes a method and apparatus for managing a service in a service layer. In particular, a method describes a computer readable storage medium including instructions for managing a service in a service layer where the instructions are executed by a processor. The executed instructions cause the processor to receive a request to manage, via a service enabler function of the service layer, a change of state of the service including adding, removing, activating, or deactivating the service. The request may include a service description. The executed instructions also cause the processor to evaluate, via the service enabler function, the service description comprising identifiers of one or more services to manage. The executed instructions further cause the processor to identify one or more service capabilities in the service layer to assist in managing the one or more services identified in the service description.

Abstract: Computer-implemented methods for generating neural networks, and methods for classifying physiological data and patients based on the generated networks, are provided. The methods comprise determining values of a plurality of hyperparameters based on one or more properties of the received input data, which may be physiological data. A neural network comprising a plurality of layers is generated based on the hyperparameters, and is trained using the input data. If a first predetermined condition is not met, the values of one or more of the hyperparameters are updated. The steps of generating and training a neural network are repeated until the first predetermined condition is met. When the first predetermined condition is met, one of the trained neural networks is selected and is output.

Abstract: A material collection system is provided. The system can include a vacuum generator having a fan to develop an airflow and draw material into a conduit. The system can also include a transmission, a power source to selectively power at least one of the vacuum generator and the transmission, a variable power divider to divide a power output from the power source to the transmission and the vacuum generator, and a control system to control the variable power divider in a first mode and a second mode.

Abstract: A combination of medications and medication doses is disclosed whereby age-related changes in systemic inflammation, cancer risk, heart disease risk, CD38 expression, hair color, thymotrophic hormones, immune cell populations, the CD4/CD8 cell ratio, bone marrow density, thymus structure, kidney function, and epigenetic age can be reversed in humans. Surprisingly, agents that accelerate the growth of cells reduce cancer risk, agents that intensify immune responses attenuate age-related inflammation, agents with no prior connection to hair color reverse age-related hair whitening, and a combination of agents that induces IGF-1, a hormone previously thought to drive systemic aging, results in a reversal of systemic aging as documented by an epigenetic clock. Medication combinations useful in the present invention include human growth hormone (GH) or GH releasers, dehydroepiandrosterone (DHEA), and metformin.

Abstract: A surgical imaging system includes at least one camera apparatus having a camera body including an image sensor configured to capture image data in a field of view. A scope extends along a longitudinal axis from the camera body. A camera orientation sensor is in connection with the camera apparatus. The camera orientation sensor detects a camera orientation of the camera apparatus. A scope orientation sensor detects a scope orientation of the scope relative to the camera body. A controller monitors the camera orientation and the scope orientation. In response to a change in the scope orientation relative to the camera orientation, the controller updates a rotation of the field of view of the image data.

Abstract: A self-leveling container system may include a container and a lid. The lid may include a leveling mechanism coupled to a first portion of the lid a distance from a front edge of the first portion. The lid may include a second portion rotatably coupled to the first portion. The leveling mechanism may be configured to contact a scoop to remove excess of one or more substances in a scoop when the scoop is removed from the recess.

Abstract: A method for splitting a semi-finished product includes placement of the semi-finished product on a splitting template, and the splitting template includes at least one elevation. The method includes fixation of the semi-finished product on the splitting template, in which an area of the semi-finished product is arranged on the elevation. The method includes splitting of the semi-finished product, in which material is removed from the semi-finished product during splitting. The material removal in the area that is arranged on the elevation is greater than in an area that is not arranged on the elevation.

Abstract: The present invention provides a system and methods for the detection of peptides from and antibodies against coronaviruses, filoviruses, flaviviruses, or combination thereof, in a sample. A method for detecting the presence of a coronavirus in a sample may comprise: collecting a small sample of a biological fluid from the test subject, adding sample to a viral test cassette, initiating sample processing by the assay cassette to incubate the diluted sample and developing reagents with an antibody microarray contained within the cassette, and results of the test are read by visual examination and process the results to determine if the subject is infected by a coronavirus.

Abstract: A functionally graded structure for a protective device includes a plurality of lattice structures including at least a first lattice structure having a first geometry and a second lattice structure having a second geometry. The first lattice structure with the first geometry has a first compression response property and the second lattice structure with the second geometry has a second compression response property that is different from the first compression response property.

Abstract: A roller spinning assembly includes a roller frame and a spindle connected to the roller frame. The spindle is “locked” to the roller frame such that the spindle does not rotate independently of the roller frame. To clean the roller, the roller is fitted onto the roller frame, the spindle is fitted to the drill, and the roller, roller frame, and a portion of the spindle are immersed in water within a bucket. The drill spins the spindle, roller frame, and roller, and the spinning of the roller within the water acts to clean the roller quickly, removing paint and other extraneous material from the roller. The roller spinning assembly also has applications for mixing paint, as well as for mixing drywall mix and similar materials.

Abstract: Disclosed are new configurations of a rubidium elution system that offer several advantages. The rubidium elution systems of the present disclosure comprise an assembly including a 82Sr/82Rb generator, an activity detector, a waste container, a pump, a sensor, a tubing circuit and at least one valve. The waste container is located in the lower section of the assembly. More particularly, the top surface of the waste container compartment is either below the top surface of the generator compartment, or the waste container is at the same elevation than the generator or below the pump.