Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.

Abstract: A percutaneous cannula is provided for the exchange of blood within a patient's vasculature. The cannula includes a main cannula portion and a tip portion. The main cannula portion comprises a proximal portion, a distal portion, a first lumen, and a second lumen extending through the proximal portion. The tip portion extends from the main cannula portion to a distal end of the cannula. The tip portion comprises a discharge opening and a redirecting member. The redirecting member is configured to direct blood flow being discharged through the discharge opening proximally along the cannula. At least one of the first and second lumens is configured to reduce the effect of flow resistance therein.

Abstract: A multilumen cannula is provided that directs blood through a patient through a single cannulation site. The multilumen cannula has a first elongate portion and a second elongate portion. The first elongate portion defines a first lumen that extends between a first proximal end and a first distal end. The second elongate portion defines a second lumen that extends between a second proximal end and a second distal end. The inner cross-section of the first lumen is greater at the first distal end than at the first proximal end.

Abstract: A cannula system includes a multilumen cannula and a dilator. The multilumen cannula includes a first elongate body and a second elonaget body. The first elongate body has a proximal portion, a distal portion, and a first lumen that extends through the first elongate body. The first lumen is configured to reduce resistance to flow therethrough. The second elongate body defines a second lumen. The second elongate body extends along the proximal portion of the first elongate body. The dilator is configured to extend through the first lumen.

Abstract: A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent.

Abstract: A perfusion cannula system for directing blood through the vasculature of a patient comprises a cannula body having a proximal end, a distal end, and at least one lumen extending therebetween. The perfusion cannula system enhances blood flow past the cannula when the cannula body resides within the patient. A first balloon can be located on an exterior surface of the cannula body and the balloon can be deployed within the vasculature whereby space may be provided between a vessel wall and the cannula body. A cannula body can have an aperture formed therein in fluid communication with a lumen. A sleeve can be carried by the cannula and can be configured to be moveable relative to the aperture to selectively cover and uncover the aperture as desired.

Abstract: A percutaneous cannula is provided that directs blood into a vessel of a patient. The cannula includes a main cannula portion and a tip portion. The tip portion directs blood-flow in a direction generally counter to the direction of flow through the lumen. The cannula is configured to prevent blood-flow exiting the distal end from immediately discharging against a wall of the vessel.

Abstract: A multiple lumen access device for use in providing a single entry port into the human body for selectively introducing medical implements therethrough and for providing simultaneous auxiliary access into the body. The multiple lumen access device includes a multi-lumen sheath which may have an outer tube and structure defining a device lumen located therein. The inner structure may be an inner wall or inner tube. The outer tube and inner structure are located so as to define at least one auxiliary lumen. Some embodiments include flexible inner walls which can be flexed between relaxed and expanded/contracted positions wherein the relative cross-sectional areas of the device lumen and auxiliary lumens are varied. The access device further includes a valve which provides sealing of the device lumen. The valve may be provided in a lumen junction housing or separate from the housing either permanently or removably connected with the device lumen.

Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.

Abstract: A multiple lumen access device for use in providing a single entry port into the human body for selectively introducing medical implements therethrough and for providing simultaneous auxiliary access into the body. The multiple lumen access device includes a multi-lumen sheath which may have an outer tube and structure defining a device lumen located therein. The inner structure may be an inner wall or inner tube. The outer tube and inner structure are located so as to define at least one auxiliary lumen. Some embodiments include flexible inner walls which can be flexed between relaxed and expanded/contracted positions wherein the relative cross-sectional areas of the device lumen and auxiliary lumens are varied. The access device further includes a valve which provides sealing of the device lumen. The valve may be provided in a lumen junction housing or separate from the housing either permanently or removably connected with the device lumen.

Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.

Abstract: A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent.

Abstract: An introducer sheath for a central venous catheter includes a sheath body and a temperature sensor mounted distally on the body. Either the catheter or sheath has a heat exchange region through which coolant is circulated to effect heat exchange with the body, with the coolant temperature being controlled in response to signals from the temperature sensor. Arterial dialysis heat exchange catheters and jugular bulb heat exchange catheters are also disclosed.

Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.

Abstract: A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent.

Abstract: An over-the-wire heat exchange catheter includes a heat transfer extension having at least one supply lumen and at least one return lumen for circulating heat exchange fluid within the catheter. The catheter has a distal tip and valve attached to the distal tip. The valve automatically seals the distal tip around a guidewire or a mandrel to seal the heat transfer extension and inhibit escape of the heat transfer fluid from the heat transfer extension.

Abstract: A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and/or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end with first and second lumens extending from the proximal end to each of these distal ends to provide for blood circulation within one blood vessel or between two different blood vessels. The second lumen, and any additional lumens so desired, may be positioned coaxially with or radially around the first lumen. Redirecting means is provided at a distal end of at least one of said lumens for directing blood in a direction generally opposite of the direction of flow through said lumen.

Abstract: An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart.

Abstract: An introducer sheath for a central venous catheter includes a sheath body and a temperature sensor mounted distally on the body. Either the catheter or sheath has a heat exchange region through which coolant is circulated to effect heat exchange with the body, with the coolant temperature being controlled in response to signals from the temperature sensor. Arterial dialysis heat exchange catheters and jugular bulb heat exchange catheters are also disclosed.

Abstract: The method, device and system for electrical sealing of a puncture opening in a blood vessel wall. In a first embodiment, a vascular sealing probe has two bipolar electrodes formed thereon, is insertable to a position whereat the bipolar tip is adjacent the blood vessel puncture site to effect electrocauterization or electrocoagulation of the puncture site. In a second embodiment the bipolar vascular sealing probe has a first electrode formed thereon and an electrode-guide wire has the second bipolar electrode formed thereon. The electrode-guide wire is passable through a lumen formed in the probe such that the second electrode on the electrode-guide wire is positioned close enough to the first electrode positioned on the probe to permit electrical current to pass therebetween.