Abstract: A method for applying a surface treatment to a plugged honeycomb body comprising porous wall includes: mixing particles of an inorganic material with a liquid vehicle and a binder material to form a liquid-particulate-binder stream; mixing the liquid-particulate-binder stream with an atomizing gas, directing the liquid-particulate-binder stream into an atomizing nozzle thereby atomizing the particles into liquid-particulate-binder droplets comprised of the liquid vehicle, he binder material, and the particles; conveying the droplets toward the plugged honeycomb body by a gaseous carrier stream, wherein the gaseous carrier stream comprises a carrier gas and the atomizing gas; evaporating substantially all of the liquid vehicle from the droplets to form agglomerates comprised of the particles and the binder material; depositing the agglomerates onto the porous walls of the plugged honeycomb body; wherein the deposited agglomerates are disposed on, or in, or both on and in, the porous walls.

Abstract: A glass body that includes titania and silica, wherein an average hydroxyl concentration amongst a plurality of segments of the glass body is from about 0 ppm to about 100 ppm and a peak-to-valley of hydroxyl concentration amongst the plurality of segments is about 60 ppm or less, the hydroxyl concentration being measured using a Fourier transform infrared spectroscopy in transmission, and the plurality of segments including every adjacent segment across a length and a width of the glass body, the length being about 25 mm or more and the width being about 25 mm or more, and the glass body comprising a chlorine concentration of about 100 ppm or less.

Abstract: A filtration article having a honeycomb filter body that includes a plurality of intersecting porous walls including surfaces that define a plurality of channels extending in a longitudinal direction from an inlet end to an outlet end. The plurality of channels includes inlet channels that are open at the inlet end and sealed at locations longitudinally spaced away from the inlet end, and outlet channels that are open at the outlet end and sealed at locations longitudinally spaced away from the outlet end. Inorganic deposits are disposed on, or in, or both on and in, at least some of the walls. The inorganic deposits are bound to each other, to the walls, or to both, by a silicon-containing precursor binder.

Abstract: A method for applying a surface treatment to a plugged honeycomb body comprising porous wall includes: mixing particles of an inorganic material with a liquid vehicle and a binder material to form a liquid-particulate-binder stream; mixing the liquid-particulate-binder stream with an atomizing gas, directing the liquid-particulate-binder stream into an atomizing nozzle thereby atomizing the particles into liquid-particulate-binder droplets comprised of the liquid vehicle, the binder material, and the particles; conveying the droplets toward the plugged honeycomb body by a gaseous carrier stream, wherein the gaseous carrier stream comprises a carrier gas and the atomizing gas; evaporating substantially all of the liquid vehicle from the droplets to form agglomerates comprised of the particles and the binder material; depositing the agglomerates onto the porous walls of the plugged honeycomb body; wherein the deposited agglomerates are disposed on, or in, or both on and in, the porous walls.

Abstract: Filtration articles herein exhibit excellent filtration efficiency and pressure drop before and after water durability testing. The articles comprise: a honeycomb filter body; inorganic deposits disposed within the honeycomb filter body at a loading of less than or equal to 20 grams of the inorganic deposits per liter of the honeycomb filter body. The inorganic deposits are comprised of refractory inorganic nanoparticles bound by a high temperature binder comprising one or more inorganic components. At least a portion of the inorganic deposits form a porous inorganic network over portions of inlet walls of the honeycomb filter body.

Abstract: A method of producing soot, including: combusting a first fuel stream and a first oxidizer at a burner face; combusting a second fuel stream and a second oxidizer at the burner face, wherein the second fuel stream and the second oxidizer are premixed in advance of the burner face and a second equivalence ratio of the second fuel stream and the second oxidizer is less than about 1; and combusting a silicon-containing fuel into a plurality of soot particles, wherein the second fuel stream and the second oxidizer are combusted between the first fuel stream and the silicon-containing fuel. Applying this method of producing soot to deposit a preform suitable for the manufacture of optical fibers.

Abstract: In some embodiments, a method for processing an optical fiber includes: drawing an optical fiber through a draw furnace, conveying the optical fiber through a flame reheating device downstream from the draw furnace, wherein the flame reheating device comprises one or more burners each comprising: a body having a top surface and an opposing bottom surface, an opening within the body extending from the top surface through the body to the bottom surface, wherein the optical fiber passes through the opening, and one or more gas outlets within the body; and igniting a flammable gas provided by the one or more gas outlets to form a flame encircling the optical fiber passing through the opening, wherein the flame heats the optical fiber by at least 100 degrees Celsius at a heating rate exceeding 10,000 degrees Celsius/second.

Abstract: Surgical instruments for interfacing with implants can include an inserter configured to dock to a unilateral portion of an implant. The inserter can include a control shaft that is configured to lock or unlock the inserter coupling with the implant. Actuation of the control shaft can occur by way of a knob that can control movement of the control shaft. The inserter can facilitate positioning of the implant relative to a surgical site and allow for application of counter-torque when imparting torque for tightening a set screw, etc. Additional instruments can also be used to manipulate the implant. For example, auxiliary instruments can be coupled to the inserter, such as a reducer instrument, to facilitate rod reduction, etc. Alternatively or in addition, a holder instrument can be used that has a threaded distal engagement feature for coupling to the implant to facilitate positioning thereof.

Abstract: This document relates to methods and materials for assessing radiation exposure. For example, methods and materials that can be used to determine whether a mammal (e.g., a human) has been exposed to radiation and/or whether a mammal (e.g., a human) is at risk of developing one or more radiation injuries (e.g., cutaneous radiation injury (CRI) and/or acute radiation syndrome (ARS)) following radiation exposure (e.g., radiation therapy) are provided.

Abstract: A method of heating an optical fiber, the method including flowing gas from a common gas channel into one or more gas outlets of a burner, the common gas channel encircling an aperture of the burner. The method further including igniting the gas to form a flame and heating the fiber with the flame as the fiber passes through the aperture. The one or more gas outlets opening into the aperture such that each gas outlet has a gas outlet bore terminating at an inward-facing wall of the burner that defines the aperture. And the gas outlet bore being oriented at an angle ?1 defined between the gas outlet bore and the inward-facing wall of the burner, downstream of the gas outlet bore, that is greater than or equal to 10 degrees and less than or equal to 70 degrees.

Abstract: Methods for producing a nanotextured surface on a substrate include forming nanoparticles from a precursor within a stream of a carrier gas. Methods include heating a surface of a substrate facing the carrier gas. Methods comprise delivering the nanoparticles to the surface of the substrate facing the carrier gas to produce the nanotextured surface.

Abstract: Methods for modifying multi-mode optical fiber manufacturing processes are disclosed. In one embodiment, a method for modifying a process for manufacturing multi-mode optical fiber includes measuring at least one characteristic of a multi-mode optical fiber. The at least one characteristic is a modal bandwidth or a differential mode delay at one or more wavelengths. The method further includes determining a measured peak wavelength of the multi-mode optical fiber based on the measured characteristic, determining a difference between the target peak wavelength and the measured peak wavelength, and modifying the process for manufacturing multi-mode optical fiber based on the difference between the target peak wavelength and the measured peak wavelength.

Abstract: A method of producing bi-modal particles includes the steps of igniting a first precursor gas using a primary burner thereby producing a first plurality of particles of a first size, fluidly transporting the first plurality of particles down a particle tube, igniting a second precursor gas using a secondary burner thereby producing a second plurality of particles of a second size, flowing the second plurality of particles into the first plurality of particles, and capturing the first and second plurality of particles.

Abstract: The disclosure provides methods for predicting surface-presenting peptides using binding and surface-presentation characteristics. The method can include accessing a trained machine-learning model that is configured to generate an output that indicates an extent to which the one or more expression levels and the one or more peptide-presentation metrics are related in accordance with a population-level relationship between expression and presentation. For each peptide of the set of peptides for a tissue sample, a score can be determined using the machine-learning model and genomic and transcriptomic data corresponding to the peptide. The score is predictive of whether a corresponding peptide is a surface-presenting peptide that binds to an MHC molecule and is presented on a cell surface.

Abstract: Methods for generating a composite biomarker that identifies a predicted level of responsiveness of a subject to a particular type of an immunotherapy treatment is provided. The method can include generating genomic metrics that represent one or more characteristics corresponding to one or more DNA sequences. The method can also include generating transcriptomic metrics represent one or more characteristics corresponding to a set of peptides that are translated from a corresponding RNA sequence of the one or more RNA sequences. The method can also include generating a composite biomarker score derived from the set of genomic metrics and the set of transcriptomic metrics. The method can also include determining, based on the composite biomarker score, a predicted level of responsiveness of the subject to a particular type of an immunotherapy treatment.

Abstract: A method of forming an optical fiber preform includes the steps: igniting a burner having a fume tube assembly to produce a first spray size of silicon dioxide particles; depositing the silicon dioxide particles on a core cane to produce a soot blank; and adjusting an effective diameter of an aperture of the fume tube assembly to produce a second spray size of the silicon dioxide particles. The second spray size is larger than the first spray size.

Abstract: A particulate filter having a porous ceramic honeycomb structure with a first end, a second end, and a plurality of walls having wall surfaces defining a plurality of inner channels. Filtration material deposits are disposed on one or more of the wall surfaces of the honeycomb body. The highly porous deposits provide durable high clean filtration efficiency with small impact on pressure drop through the filter.

Abstract: A particulate filter having a porous ceramic honeycomb structure with a first end, a second end, and a plurality of walls having wall surfaces defining a plurality of inner channels. Filtration material deposits are disposed on one or more of the wall surfaces of the honeycomb body. The highly porous deposits provide durable high clean filtration efficiency with small impact on pressure drop through the filter.

Abstract: A method of producing soot, including: combusting a first fuel stream and a first oxidizer at a burner face; combusting a second fuel stream and a second oxidizer at the burner face, wherein the second fuel stream and the second oxidizer are premixed in advance of the burner face and a second equivalence ratio of the second fuel stream and the second oxidizer is less than about 1; and combusting a silicon-containing fuel into a plurality of soot particles, wherein the second fuel stream and the second oxidizer are combusted between the first fuel stream and the silicon-containing fuel. Applying this method of producing soot to deposit a preform suitable for the manufacture of optical fibers.

Abstract: In some embodiments, a method for processing an optical fiber includes: drawing an optical fiber through a draw furnace, conveying the optical fiber through a flame reheating device downstream from the draw furnace, wherein the flame reheating device comprises one or more burners each comprising: a body having a top surface and an opposing bottom surface, an opening within the body extending from the top surface through the body to the bottom surface, wherein the optical fiber passes through the opening, and one or more gas outlets within the body; and igniting a flammable gas provided by the one or more gas outlets to form a flame encircling the optical fiber passing through the opening, wherein the flame heats the optical fiber by at least 100 degrees Celsius at a heating rate exceeding 10,000 degrees Celsius/second.