Patents by Inventor Robert S. Schwartz

Robert S. Schwartz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190082976
    Abstract: Systems and apparatus are included that are configured to determine the effectiveness of apparatus and methods used to diagnose and unblock microvascular obstruction (MVO). An infusion system blocks antegrade flow for a short time and measures vascular pressure response as an infusate is infused in stepwise fashion at increasingly higher flowrates. During the antegrade flow occlusion, calculations of the real-time vascular resistance can be obtained using the formula R(t)=(t)/Qmean(t) where: Qmean (t) is the flow mean values generated by the infusion system; P(t) is the distal pressure response in the vessel generated from the flow infusion; and R(t) is the calculated vascular resistance using the two other known parameters.
    Type: Application
    Filed: September 19, 2018
    Publication date: March 21, 2019
    Inventors: Jon Helge Hoem, Robert S. Schwartz, Martin T. Rothman
  • Patent number: 10232183
    Abstract: A method that electrically stimulates a heart muscle to alter the ejection profile of the heart, to control the mechanical function of the heart and reduce the observed blood pressure of the patient. The therapy may be invoked by an implantable blood pressure sensor associated with a pacemaker like device. In some cases, where a measured pretreatment blood pressure exceeds a treatment threshold, a patient's heart may be stimulated with an electrical stimulus timed relative to the patient's cardiac ejection cycle. This is done to cause dyssynchrony between at least two cardiac chambers or within a cardiac chamber, which alters the patient's cardiac ejection profile from a pretreatment cardiac ejection profile. This has the effect of reducing the patient's blood pressure from the measured pretreatment blood pressure.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: March 19, 2019
    Assignee: BackBeat Medical, Inc.
    Inventors: Robert S. Schwartz, Robert A. Van Tassel
  • Publication number: 20190046111
    Abstract: Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed.
    Type: Application
    Filed: October 19, 2018
    Publication date: February 14, 2019
    Inventors: Landy Toth, Robert S. Schwartz
  • Publication number: 20190046760
    Abstract: A method of detecting and treating a microvascular obstruction is provided. In one embodiment, a catheter is provided for both detecting the microvascular obstruction and treating or removing the obstruction.
    Type: Application
    Filed: October 10, 2018
    Publication date: February 14, 2019
    Applicant: Osprey Medical, Inc.
    Inventors: Robert S. Schwartz, Robert A. Van Tassel
  • Publication number: 20190001141
    Abstract: Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Patent number: 10143419
    Abstract: Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: December 4, 2018
    Assignee: AUTONOMIX MEDICAL, INC.
    Inventors: Landy Toth, Robert S. Schwartz
  • Patent number: 10136944
    Abstract: Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: November 27, 2018
    Assignee: AUTONOMIX MEDICAL, INC.
    Inventors: Landy Toth, Robert S. Schwartz
  • Patent number: 10118016
    Abstract: A method of detecting and treating a microvascular obstruction is provided. In one embodiment, a catheter is provided for both detecting the microvascular obstruction and treating or removing the obstruction.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: November 6, 2018
    Assignee: Osprey Medical, Inc.
    Inventors: Robert S. Schwartz, Robert A. Van Tassel
  • Publication number: 20180280172
    Abstract: Devices and methods for preventing reperfusion injuries when an occlusion balloon is deflated. A catheter having an infusion lumen exiting the catheter distal of a stent balloon and/or occlusion balloon allows a therapeutic agent to be introduced to a target location to establish desired temperatures and pressures prior to deflation of the balloon such that negative effects of reperfusion are minimized.
    Type: Application
    Filed: March 20, 2018
    Publication date: October 4, 2018
    Applicant: CorFlow Therapeutics AG
    Inventors: Jon H. Hoem, Robert S. Schwartz, Martin T. Rothman
  • Publication number: 20180256899
    Abstract: Systems and methods for reducing ventricle filling volume are disclosed. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated at a consistent rate to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 13, 2018
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Patent number: 10071250
    Abstract: Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: September 11, 2018
    Assignee: BackBeat Medical, Inc.
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Publication number: 20180185652
    Abstract: Systems and methods for controlling blood pressure by controlling atrial pressure and atrial stretch are disclosed. In some embodiments, a stimulation circuit may be configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient, and at least one controller may be configured to execute delivery of one or more stimulation patterns of stimulation pulses to the at least one cardiac chamber, wherein at least one of the stimulation pulses stimulates the heart such that an atrial pressure resulting from atrial contraction of an atrium overlaps in time a passive pressure build-up of the atrium, such that an atrial pressure of the atrium resulting from the stimulation is a combination of the atrial pressure resulting from atrial contraction and the passive pressure build-up and is higher than an atrial pressure of the atrium would be without the stimulation, and such that the blood pressure of the patient is reduced.
    Type: Application
    Filed: December 22, 2017
    Publication date: July 5, 2018
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Patent number: 9937351
    Abstract: Systems and methods for reducing ventricle filling volume are disclosed. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated at a consistent rate to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, a stimulation circuit may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: April 10, 2018
    Assignee: BackBeat Medical, Inc.
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Patent number: 9878162
    Abstract: Systems and methods for controlling blood pressure by controlling atrial pressure and atrial stretch are disclosed. In some embodiments, a stimulation circuit may be configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient, and at least one controller may be configured to execute delivery of one or more stimulation patterns of stimulation pulses to the at least one cardiac chamber, wherein at least one of the stimulation pulses stimulates the heart such that an atrial pressure resulting from atrial contraction of an atrium overlaps in time a passive pressure build-up of the atrium, such that an atrial pressure of the atrium resulting from the stimulation is a combination of the atrial pressure resulting from atrial contraction and the passive pressure build-up and is higher than an atrial pressure of the atrium would be without the stimulation, and such that the blood pressure of the patient is reduced.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: January 30, 2018
    Assignee: BackBeat Medical, Inc.
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Publication number: 20170304048
    Abstract: Systems and methods for controlling blood pressure via electrical stimulation of the heart are disclosed. Embodiments may include at least two different stimulation patterns, each configured to reduce blood pressure to a different degree, and may alternate between stimulation patterns based on the need of a patient, for example, alternating between day and night or between periods of strenuous and light activity. Some embodiments may take advantage of a slow baroreflex response that occurs after treatment is stopped, suspending treatment for extended periods, and then resuming treatment before blood pressure levels reach pretreatment values. Embodiments may control blood pressure by controlling atrial pressure and atrial stretch.
    Type: Application
    Filed: April 20, 2017
    Publication date: October 26, 2017
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Publication number: 20170239481
    Abstract: Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.
    Type: Application
    Filed: May 8, 2017
    Publication date: August 24, 2017
    Inventors: Yuval Mika, Darren Sherman, Robert S. Schwartz, Robert A. Van Tassel, Daniel Burkhoff
  • Publication number: 20170231490
    Abstract: Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including a head mounted display to monitor one or more physiologic signals from the face or head of the subject is disclosed. A method for analyzing an ocular parameter of the subject to determine a sympathetic and a parasympathetic outflow thereto is disclosed.
    Type: Application
    Filed: August 7, 2015
    Publication date: August 17, 2017
    Applicant: Autonomix Medical, Inc.
    Inventors: Landy Toth, Robert S. Schwartz
  • Publication number: 20170209389
    Abstract: Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed.
    Type: Application
    Filed: July 23, 2015
    Publication date: July 27, 2017
    Inventors: Landy Toth, Robert S. Schwartz
  • Publication number: 20170189654
    Abstract: MVO is treated by introducing injectate into blood vessels affected by MVO at precise flow rates, while blocking retrograde flow, such that the natural pumping of the heart aids in forcing the injectate into the affected microvessels. Monitoring pressure distal of an occlusion balloon is used to determine treatment effectiveness and heart health.
    Type: Application
    Filed: January 4, 2017
    Publication date: July 6, 2017
    Applicant: ReFlow Therapeutics AG
    Inventors: Robert S. Schwartz, Martin T. Rothman, Jon H. Hoem
  • Publication number: 20170143478
    Abstract: Heart valve regurgitation is reduced by sizing a coapting element to provide a gap between the coapting element and a heart valve when the heart is in a diastolic phase. The size of the coapting element is also selected such that the heart valve seals against the coapting element when the heart is in the systolic phase. The coapting element allows flow through the coapting element when the heart is in a diastolic phase and prevents flow through the coapting element when the heart is in a systolic phase.
    Type: Application
    Filed: November 2, 2016
    Publication date: May 25, 2017
    Inventors: ROBERT S. SCHWARTZ, ROBERT A. VAN TASSEL, STANTON J. ROWE