Abstract: The invention relates to a hinge for a door or a window, in particular designed as a roller hinge, comprising a frame hinge part with a mounting flange and a substantially cylindrical bearing, a panel hinge part (1) with a mounting flange (2) and a hinge tab (3) as well as an axle (4) pivotably connecting the two hinge parts one above the other in the vertical direction in the mounted state, with an axis pin (5) insertable into the bearing and a section with a seat (6) for the hinge tab (3) and the latter is adjustable transversely to the longitudinal axis of the axle (4) via an adjuster (7) within the seat (6). A mounting projection (8) is in the seat (6). A mounting cavity (9) is provided on the hinge tab (3) formed on the lower end face (10) of the hinge tab (3) or as an undercut cavity on the end face (11) of the hinge tab (3) facing away from the mounting flange (2) of the panel hinge part (1). In the assembled state, the mounting projection (8) comes to rest in the mounting cavity (9).

Abstract: Disclosed herein is a method for calibrating a spectrometer device. The method includes the following steps: a) illuminating at least one detector device of the spectrometer device with at least one broadband light source through at least one narrow band pass filter having a plurality of predetermined transmission bands; b) generating, by using the detector device, a plurality of detector signals depending on the illumination of step a); c) determining at least one item of wavelength calibration information, where the item of wavelength calibration information includes at least one assignment assigning wavelengths of incident light to corresponding photosensitive elements being responsive to these wavelengths; and d) determining at least one item of stray light calibration information based on the plurality of detector signals. Further disclosed herein are a system for calibrating a spectrometer device, a computer program and a computer-readable storage medium.

Abstract: Described is an apparatus for monitoring nitric oxide delivery, wherein such apparatus comprises a display that provides a visual and/or numeric indication of the calculated dose of nitric oxide. Also described is a method of monitoring nitric oxide delivery, wherein the breathing gas flow rate and therapeutic gas flow rate are measured and used to determine the calculated dose of nitric oxide, which is then displayed. In some embodiments, an alert is provided when the calculated dose rises above or falls below a predetermined level or range.

Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: An assembly is provided for use in a sports glove for use in baseball or softball. The assembly includes finger extension members that align with a wearer's thumb and fingers when worn. The finger extension members are made of a lightweight material such as a polymer and include at least one lattice portion. By including the more lightweight finger extension members, a glove including the assembly may have a lower moment of inertia about the heel to allow a fielder to more easily and quickly move his or her glove during play.

Abstract: Described herein is a detector for identifying at least one material property m. The detector includes at least one sensor element including a matrix of optical sensors, the optical sensors each having a light-sensitive area. The sensor element is configured for recording at least one reflection image of a light beam originating from at least one object. The detector includes at least one evaluation device configured for determining the material property m by evaluation of at least one beam profile of the reflection image and evaluation of a material feature ??2m.

Abstract: Described is an apparatus for monitoring nitric oxide delivery, wherein such apparatus comprises a display that provides a visual and/or numeric indication of the calculated dose of nitric oxide. Also described is a method of monitoring nitric oxide delivery, wherein the breathing gas flow rate and therapeutic gas flow rate are measured and used to determine the calculated dose of nitric oxide, which is then displayed. In some embodiments, an alert is provided when the calculated dose rises above or falls below a predetermined level or range.

Abstract: A rotor for an electric machine includes a rotor main part which has at least one pole core, at least one winding device which is received on the at least one pole core, and at least one contact device which is rotationally fixed to the rotor main part and which is coupled to the at least one winding device to conduct a current. The at least one winding device includes at least one winding that is plugged onto the at least one pole core and has two winding wire ends, at least one winding wire end of which is coupled to the at least one contact device to conduct a current via at least one plug connection.

Abstract: Compounds of formula I and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: A salient pole rotor includes a rotor core which has a rotor yoke and salient poles arranged distributed over the rotor yoke in the circumferential direction, magnetic field-generating windings which are wound around rotor teeth of the salient poles and form end windings at opposite end sides of the rotor core, and a support device for supporting the end windings. The support device has a clamping and deflecting device and a roving winding with a roving by way of which a plurality of turns offset in the circumferential direction and encompassing the windings of a respective salient pole pair are formed and which for this purpose has axial first roving portions and end-side second roving portions. The second roving portions are guided over the end windings for forming a turn between radially opposite salient poles and are deflected along the circumferential direction for forming an interturn transition between two turns.

Abstract: The present invention provides novel compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of cyclin-dependent kinase 7 (CDK7), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.

Abstract: A rotor, a corresponding electric machine, a manufacturing method and a corresponding motor vehicle are disclosed. The rotor has a cavity structure in a first winding head supporting structure and a cut-out in a second winding head supporting structure which are connected by way of feed and return lines for a coolant. Here, the cavity structure has an inflow region, into which a coolant guide of a rotor shaft opens, and a return region which is separate from the inflow region. In this way, the rotor is configured for liquid cooling of the winding head supporting structure.

Abstract: A one-way passage system (1) comprises an entrance door arrangement (2a) and offset therefrom an exit door arrangement (2b). First and second side wall arrangements (3a, 3b) are provided therebetween, thereby defining a passage area (4). A sensor device (5) can detect persons (10): a) before the entrance door arrangement (2a); b) in the passage area (4) and/or after the exit door arrangement (2b). A control device is configured to enter a safety operating mode and to close the entrance door arrangement (2a) when an analysis of sensor data indicates that a person (10): a) in the passage area (4) goes back in the direction of the entrance door arrangement (2a); and/or b) goes back after the exit door arrangement (2b) in the direction of the passage area (4). An illumination device (20), which is arranged in the passage area (4) can illuminate the passage area in different colors.

Abstract: The invention relates to a rotor (20) for an electric machine (10), comprising:—at least one rotor laminated core (30) that has at least one coil receiving opening (40);—at least one coil device (50) which is located in the at least one coil receiving opening (40); and—at least one holding device (70) which is joined to the rotor laminated core (30) and prevents an outward movement (B), brought about by centrifugal force, of the at least one coil device (50) in the radial extension direction (R) of the rotor (20) and out of the at least one coil receiving opening (40) during normal use of the electric machine (10).

Abstract: In a device and method for determining a contact between a tool and a workpiece, which are displaceable relative to each other, the tool or workpiece being rotationally fixedly connected to a shaft, the device includes a measuring arrangement including a measuring scale rotationally fixedly disposed on the shaft and at least one position encoder disposed in a stationary manner relative to the shaft, and a processing device. The position encoder is adapted to scan the measuring scale and to generate position values indicating a position of the shaft. The position values are fed to the processing device, which determines contact between the tool and the workpiece by evaluating a progression of the position values and signals the result of the evaluation by the status of a displacement signal.

Abstract: A respiratory treatment device having an inlet configured to receive exhaled air into the device, an outlet configured to permit exhaled air to exit the device, a valve moveable in response to a threshold exhalation pressure at the inlet between a closed position where the flow of air from the inlet to the outlet is restricted, and an open exhalation position where the flow of air from the inlet to the outlet is less restricted, and a valve brace configured to support the valve, wherein a position of the valve brace relative to the valve is selectively adjustable to increase or decrease the threshold exhalation pressure.

Abstract: Compounds of formula I and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.