Abstract: In an example embodiment, a solution is provided that places all threads under control to prevent a scenario where a thread attempts to access memory that has already been released as part of a large computer system shutdown. While this solution address potential instability caused by a parallel processing shutdown technique, it can also be more broadly applied in any large computer system shutdown process to prevent crashes or other issues.

Abstract: Electroporation is a technique in which an electrical field is applied to cells in order to increase the permeability of the cell membrane. This allows for chemicals, drugs, and/or macromolecules such as proteins and nucleic acids to be introduced into the cells. Embodiments relate to an electroporation apparatus. The electroporation apparatus comprises: a plurality of chambers configured to store a plurality of cells during an electroporation process; a plurality of electrodes configured to generate a plurality of electric fields within the plurality of chambers during the electroporation process, each electric field of the plurality of electric fields corresponding to one chamber of the plurality of chambers; a flow channel configured to transport the plurality cells during a cell collection process after the electroporation process; and a plurality of valves connecting the plurality of chambers to the flow channel.

Abstract: A method includes: obtaining an ultrasound image of an anatomical area from an ultrasound imaging device; inputting the ultrasound image into a first stage of a convolutional neural network, the first stage configured to determine key-point locations of the anatomical area; generating, for each of the key-point locations, a cropped region of the ultrasound image; inputting each of the cropped regions into a second stage of the convolutional neural network, the second stage configured to locate an anatomical landmark of the anatomical area; and outputting a location of the anatomical landmark.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: Technology for guiding a user to collect clinically usable ultrasound images is described. In some embodiments, an ultrasound device may automatically change the elevational steering angle of its ultrasound beam (e.g., using beamforming) in order to collect ultrasound data from different imaging planes within the subject. A processing device in operative communication with the ultrasound device may select one of the collected ultrasound images based on its quality (e.g., select the ultrasound image having the highest quality), and then continue to collect ultrasound images using the elevational steering angle at which the selected ultrasound image was collected.

Abstract: A universal ferrule element for an arrowhead having a front end and an opposed rear end. The rear end is threaded and is configured to be coupled to a shaft of the arrow, and the front end has a first fastener-receiving opening and a first slot that communicates with the first fastener-receiving opening and that is sized and configured for mounting a first fixed blade. The universal ferrule element also includes a second slot formed in and extending longitudinally along the front end that is sized and configured for seating one or more of a fixed body blade, one or more front deployable blades, and one or more rear deployable blades. The universal ferrule element can also include and second and third fastener-receiving openings formed in the front end and positioned to communicate with the longitudinally extending slot.

Abstract: Technology for guiding a user to collect clinically usable ultrasound images is described. In some embodiments, an ultrasound device may automatically change the elevational steering angle of its ultrasound beam (e.g., using beamforming) in order to collect ultrasound data from different imaging planes within the subject. A processing device in operative communication with the ultrasound device may select one of the collected ultrasound images based on its quality (e.g., select the ultrasound image having the highest quality), and then continue to collect ultrasound images using the elevational steering angle at which the selected ultrasound image was collected.

Abstract: A drinking system comprises a lid and an aroma container. The lid is attachable to the opening of a drinking vessel having an interior volume for a drinking liquid. The lid also has a transport channel for the drinking liquid leading to a drinking opening and an attachment structure for attaching the aroma container to the lid. The aroma container has a first wall, a second wall essentially parallel to the first wall, at least one sidewall connecting the first wall and the second wall, an air inlet opening and an air outlet opening. The lid has an aroma channel with a first end and a second end. The aroma channel is arranged and configured such that aromatized air leaving the air outlet opening enters the aroma channel through the first end, and leaves the aroma channel through the second end which is in communication with an opening into the transport channel for the drinking liquid.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: A method for use in generating a computer-based visualization of 3D medical image data is described. The method includes receiving 3D medical image data and performing a selection process to select first image data forming a first portion of the 3D medical image data, the first image data representing a first anatomical object of a given type. An analysis process is performed on the first image data, a parameter of the analysis process being based on the given type of the first anatomical object. Based at least in part on a result of the analysis process, a visual parameter mapping for the first portion is determined, for use in a rendering process for generating a visualization of the 3D medical image data. Also described is a method of generating a computer-based visualization of 3D medical image data and an apparatus for performing the methods.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: A computer-implemented method and a corresponding apparatus are provided for the provision of a two-dimensional visualization image having a plurality of visualization pixels for the visualization of a three-dimensional object represented by volume data for a user. Context information for the visualization is obtained by the evaluation of natural language and is taken into account in the visualization. The natural language can be in the form of electronic documents, which are assigned or can be assigned to the visualization process. In addition, the natural language can be in the form of a speech input of a user, during or after the visualization.

Abstract: A method includes: obtaining an ultrasound image of an anatomical area from an ultrasound imaging device; inputting the ultrasound image into a first stage of a convolutional neural network, the first stage configured to determine key-point locations of the anatomical area; generating, for each of the key-point locations, a cropped region of the ultrasound image; inputting each of the cropped regions into a second stage of the convolutional neural network, the second stage configured to locate an anatomical landmark of the anatomical area; and outputting a location of the anatomical landmark.

Abstract: A removable cable connector engages with an electronic device such that the removable cable connector removably yet securely attaches to the electronic device. In some embodiments, the electronic device includes a plate configured to guide an electronic plug of the removable cable connector toward an electronic receptacle of the electronic device. The plate may be further configured to include one or more locators for holding the electronic receptacle of the electronic device in place. The removable cable connector may include a molded housing formed using a two-shot overmolding process to form a first overmolded strain relief portion and a second overmolded strain relief portion which cover fasteners that fasten a face plate to the connector.

Abstract: Ergonomic attachments for a handheld ultrasound probe are described herein. An attachment assembly includes a plate-shaped member that includes a passage configured to accommodate the handheld ultrasound probe such that when the plate-shaped member is inserted in the attachment assembly, a portion of a transducer head of the handheld ultrasound probe protrudes from the plate-shaped member. Another attachment assembly includes a shell that attaches to the handheld ultrasound probe and partially covers the handheld ultrasound probe, and strap anchors that are each connected to the shell and are disposed at opposite ends of the shell. Another attachment includes a curved bar that is continuous between a proximal attachment flange, of the curved bar, that attaches to a first location of the handheld ultrasound probe and a distal attachment flange, of the curved bar, that attaches to a second location of the handheld ultrasound probe.

Abstract: Aspects of the technology described herein relate to techniques for guiding an operator to use an ultrasound device. Thereby, operators with little or no experience operating ultrasound devices may capture medically relevant ultrasound images and/or interpret the contents of the obtained ultrasound images. For example, some of the techniques disclosed herein may be used to identify a particular anatomical view of a subject to image with an ultrasound device, guide an operator of the ultrasound device to capture an ultrasound image of the subject that contains the particular anatomical view, and/or analyze the captured ultrasound image to identify medical information about the subject.

Abstract: The present disclosure is a handheld apparatus that vaporizes plant-based or synthetic compounds, for the purpose of inhalation, or diffusion into an external environment. More specifically, the disclosure describes a handheld apparatus wherein a laser beam from an internal laser unit heats compounds, such as dried plant, tinctures, resins, or essential oils, to the compound's vaporization temperature for inhalation, or diffusion as part of aromatherapy or other holistic therapeutic treatments.

Abstract: Aspects of the technology described herein relate to techniques for guiding an operator to use an ultrasound device. Thereby, operators with little or no experience operating ultrasound devices may capture medically relevant ultrasound images and/or interpret the contents of the obtained ultrasound images. For example, some of the techniques disclosed herein may be used to identify a particular anatomical view of a subject to image with an ultrasound device, guide an operator of the ultrasound device to capture an ultrasound image of the subject that contains the particular anatomical view, and/or analyze the captured ultrasound image to identify medical information about the subject.

Abstract: Aspects of the technology described herein relate to techniques for guiding an operator to use an ultrasound device. Thereby, operators with little or no experience operating ultrasound devices may capture medically relevant ultrasound images and/or interpret the contents of the obtained ultrasound images. For example, some of the techniques disclosed herein may be used to identify a particular anatomical view of a subject to image with an ultrasound device, guide an operator of the ultrasound device to capture an ultrasound image of the subject that contains the particular anatomical view, and/or analyze the captured ultrasound image to identify medical information about the subject.

Abstract: Technology for guiding a user to collect clinically usable ultrasound images is described. In some embodiments, an ultrasound device may automatically change the elevational steering angle of its ultrasound beam (e.g., using beamforming) in order to collect ultrasound data from different imaging planes within the subject. A processing device in operative communication with the ultrasound device may select one of the collected ultrasound images based on its quality (e.g., select the ultrasound image having the highest quality), and then continue to collect ultrasound images using the elevational steering angle at which the selected ultrasound image was collected.