Abstract: Provided herein are methods of employing pharmacodynamics regimens to maximize effectiveness of voclosporin in treatment of proteinuric kidney diseases while minimizing undesirable side effects, such as but not limited to calcineurin inhibitor nephrotoxicity. Also provided are methods of assessments of renal functions and/or conditions, and corresponding protocols to modify, stop, restore and/or re-initiate voclosporin dosing and administrations to maximize effectiveness of voclosporin in treatment of proteinuric kidney diseases while minimizing undesirable side effects.

Abstract: A face mask is configured in a two-piece form, with an upper portion that covers the nose (and remains in place at all times) and a lower portion that covers the mouth, where the lower portion may be moved (released) to expose the mouth area, without needing to completely remove the mask, as typical in the prior art. A releasable attachment is formed between the bottom area of the upper portion and the top area of the lower portion. The releasable attachment may take many forms, such as a hook-and-loop arrangement, a releasable adhesive, snap connections, and the like.

Abstract: A secure terminal configured to support a trusted execution environment that utilizes policy enforcement to filter and authorize transmissions received from a host device and destined for a remote device. Upon receiving a transmission from the host device, the secure terminal verifies that the instruction, message, or request contained within the transmission satisfy parameters set by a policy. If the transmission satisfies the parameters, then the secure terminal signs the transmission with a key unique to the trusted platform module associated with the secure terminal and forwards the signed transmission to the remote device. If the transmission fails one or more parameters within the policy, a message that details the instruction or operation contained within the transmission is exposed to a user at an output device, in which the user can authorize or reject the transmission using an input device.

Abstract: A sieve bend can include a support structure supporting a screening arrangement. The screening arrangement can include a first screening segment having a first screening element configuration and at least one further screening segment having a second screening element configuration different from the first screening element configuration.

Abstract: A screen includes a support structure. A plurality of elongate screening elements are arranged in spaced relationship transversely on the support structure to define elongate screening apertures between adjacent screening elements. Each screening element has a screening head defining a screening surface, the screening surfaces all being at the same height relative to the support structure. Adjacent screening elements are of different widths relative to each other with a transverse dimension of the aperture being less than a width dimension of the wider screening element. The screening head of the wider screening element is shaped to maintain a substantially constant screening aperture between the screening elements during a predetermined amount of wear of the wider screening element.

Abstract: A secure terminal configured to support a trusted execution environment that utilizes policy enforcement to filter and authorize transmissions received from a host device and destined for a remote device. Upon receiving a transmission from the host device, the secure terminal verifies that the instruction, message, or request contained within the transmission satisfy parameters set by a policy. If the transmission satisfies the parameters, then the secure terminal signs the transmission with a key unique to the trusted platform module associated with the secure terminal and forwards the signed transmission to the remote device. If the transmission fails one or more parameters within the policy, a message that details the instruction or operation contained within the transmission is exposed to a user at an output device, in which the user can authorize or reject the transmission using an input device.

Abstract: A sieve bend can include a support structure supporting a screening arrangement. The screening arrangement can include a first screening segment having a first screening element configuration and at least one further screening segment having a second screening element configuration different from the first screening element configuration.

Abstract: A screen includes a support structure. A plurality of screening elements is arranged in spaced relationship on the support structure to define screening apertures between adjacent screening elements. Each screening element defines a screening surface, respectively. The screening surface of each of at least some of the screening elements are spaced further from the support structure than the screening surface of each of the remaining screening elements so that, on opposed sides of each screening aperture associated with the at least some of the screening elements, the screening surfaces are at different heights.

Abstract: An external storage device for holding bullets. The storage device snaps into a conventional lower receive on the firearm. The bullets are mounted in slots that are provided on the outside of the storage device. This device is intended for use with very large caliber bullets, such as .50 caliber bullets, for which there is no ammunition clip. The external storage device may also be constructed as an ammunition magazine that automatically loads bullets into the firearm, whereby the ammunition magazine is modified to include bullet storage slots on external surfaces that remain exposed when the magazine is inserted into lower receiver. The external storage device may also be constructed as a sleeve that fits over a conventional ammunition clip.

Abstract: A valve repair tool is a rod having a forked valve stem extractor on one end and a cap at the other end with a flare fitting rounding part built into it.

Abstract: An external storage device for holding bullets. The storage device snaps into a conventional lower receive on the firearm. The bullets are mounted in slots that are provided on the outside of the storage device. This device is intended for use with very large caliber bullets, such as 0.50 caliber bullets, for which there is no ammunition clip. The external storage device may also be constructed as an ammunition magazine that automatically loads bullets into the firearm, whereby the ammunition magazine is modified to include bullet storage slots on external surfaces that remain exposed when the magazine is inserted into lower receiver. The external storage device may also be constructed as a sleeve that fits over a conventional ammunition clip.

Abstract: Solidification of water treatment wastewater brines from oil production operations. Concentrated wastewater brines from water treatment systems in heavy oil recovery operations are converted to solids suitable for landfill using Portland cement. The solidification process eliminates expensive drying equipment for wastewater brine solids, as well as the associated operation and maintenance of expensive dewatering equipment.

Abstract: High availability is provided in a multi-array storage system at the logical storage unit level. One or more storage arrays export logical storage units (LUNs). Each storage array maps the LUNs to physical groups of disks or disk partitions within the array. A controller coupled to the storage arrays arranges the LUNs from all the arrays so that one or more LUN(s) are designated as spare LUN(s). If a disk failure occurs within any disk in any array, the contents of one or more of the LUN(s) associated with the group of disks containing the failed disk are re-established on the spare LUN(s). If the physical groups of disks are RAID protected, then after affected LUNs are moved, the storage array containing the failed disk removes the failed disk from its group and re-establishes RAID protection across the remaining disks in the group.

Abstract: Solidification of water treatment wastewater brines from oil production operations. Concentrated wastewater brines from water treatment systems in heavy oil recovery operations are converted to solids suitable for landfill using Portland cement. The solidification process eliminates expensive drying equipment for wastewater brine solids, as well as the associated operation and maintenance of expensive dewatering equipment.

Abstract: An aqueous dispersion comprising: a) from 5 to 99.9% by weight, based on the weight of solids in the aqueous dispersion, of one or more polymers having a number average molecular weight less than 10,000; b) from 0.1 to 94.9% by weight, based on the weight of solids in the aqueous dispersion, of one or more active ingredients selected from the group consisting of water soluble active ingredients, partially water soluble active ingredients, water insoluble active ingredients and combinations thereof; and c) from 30% to 95% by weight of water.

Abstract: A storage processor particularly suited to RAID systems provides high throughput for applications such as streaming video data. An embodiment is configured as an ASIC with a high degree of parallelism in its interconnections. The communications architecture provides saturation of user data pathways with low complexity and low latency by employing multiple memory channels under software control, an efficient parity calculation mechanism and other features.

Abstract: A formulation for repelling particulate matter on the surface of a coating comprising polymeric nanoparticles having a mean particle diameter of from 1 to 50 nm. The polymeric nanoparticles may further be functionalized to impart additional characteristics to modify the surface of the dried coating to minimize the chances for particles to become embedded or attached to the coating.

Abstract: An aqueous abrasive-free composition is useful for chemical mechanical polishing of a patterned semiconductor wafer containing a nonferrous metal. The composition comprises an oxidizer, an inhibitor for the nonferrous metal, 0 to 15 weight percent water soluble modified cellulose, 0 to 15 weight percent phosphorus compound, 0.005 to 5 weight percent of an amphiphilic polymer, the amphiphilic polymer having an ionic hydrophilic portion with a carbon number of 2 to 250 and water.

Abstract: A leaf spring connection assembly (200) for coupling a leaf spring (202) to a vehicle is disclosed. The assembly includes a leaf spring having a spring eye (210) and a vehicle bracket (204) having a pair of recesses (214). The assembly further includes a pin (206) disposed through the spring eye. The pin includes end portions (224) which extend outward of the spring eye and which are at least partially received by the recesses of the vehicle bracket. Each of the end portions includes an annular groove (226). The assembly additionally includes a fastener (228) at least partially received in one of the annular grooves and coupled to the vehicle bracket to sandwich the pin between the vehicle bracket and the fastener.

Abstract: The present invention provides for a method for treating an ischemic disorder in a subject which comprises administering to the subject a pharmaceutically acceptable Factor IXa compound in a sufficient amount over a sufficient time period so as to treat the ischemic disorder in the subject. The invention further provides a method for treating an ischemic disorder in a subject which comprises administering to the subject a pharmaceutically acceptable form of inactivated Factor IXa in a sufficient amount over a sufficient period of time to inhibit coagulation so as to treat the ischemic disorder in the subject.