Patents by Inventor Robert W. Dugger

Robert W. Dugger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for 5-fluoro-6-chlorooxindole
    Patent number: 5210212
    Abstract: Process for the production of 5-fluoro-6-chloro- oxindole, (III), which is useful in the synthesis of certain analgesic and antiinflammatory agents, via two different synthetic pathways.Compounds of formula (I) and (II) shown below ##STR1## which are intermediates in the process of this invention.
    Type: Grant
    Filed: August 14, 1992
    Date of Patent: May 11, 1993
    Assignee: Pfizer Inc
    Inventor: Robert W. Dugger
  • Intermediates for 5-fluoro-6-chlorooxindole
    Patent number: 5166401
    Abstract: Process for the production of 5-fluoro-6-chlorooxindole, (III), which is useful in the synthesis of certain analgesic and antiinflammatory agents, via two different synthetic pathways.Compounds of formula (I) and (II) shown below ##STR1## which are intermediates in the process of this invention.
    Type: Grant
    Filed: June 25, 1991
    Date of Patent: November 24, 1992
    Assignee: Pfizer Inc
    Inventor: Robert W. Dugger
  • Intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates
    Patent number: 5166400
    Abstract: Process and intermediates for isopropyl 3S-amino-4-cyclohexyl-2R-hydroxybutyrate and 3S-amino-2R-hydroxy-5-methylhexanoate from R-malic acid. These products are of known utility in the synthesis of certain renin inhibitors.
    Type: Grant
    Filed: July 18, 1991
    Date of Patent: November 24, 1992
    Assignee: Pfizer Inc.
    Inventor: Robert W. Dugger
  • Processes for (3S,4R)-3-[1(R)-t-butyl-dimethylsilyloxy)-ethyl]-4-[1-oxo-3-thiolanylthi o(thiocarbonyl)thio]azetidin-2-ones and intermediates therefor
    Patent number: 5075439
    Abstract: Improved processes for preparation of racemic, cis- and optically active (3S,4R)-3[1(R)-t-butyl-dimethylsilyloxy)-ethyl]-4-[1-oxo-3-thiolanylthio(t hiocarbonyl)thio]azetidin-2-ones, process improvements for certain intermediates therefor and a novel intermediate for said racemic, cis- and trans-compounds, which compounds are useful as intermediates for antibacterial 5R,6S-6-[1(R)-hydroxyethyl]-2-(1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids and the pharmaceutically-acceptable salts and the pivaloyloxymethyl esters thereof.
    Type: Grant
    Filed: January 18, 1991
    Date of Patent: December 24, 1991
    Assignee: Pfizer Inc.
    Inventors: Frank R. Busch, Robert W. Dugger, George J. Quallich
  • Process for isopropyl 3S-amino-2R-hydroxy-alkanoates
    Patent number: 5036155
    Abstract: Process and intermediates for isopropyl 3S-amino-4-cyclohexyl-2R-hydroxybutyrate and 3S-amino-2R-hydroxy-5-methylhexanoate from R-malic acid. These products are of known utility in the synthesis of certain renin inhibitors.
    Type: Grant
    Filed: July 31, 1990
    Date of Patent: July 30, 1991
    Assignee: Pfizer Inc.
    Inventor: Robert W. Dugger
  • Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates
    Patent number: 4965372
    Abstract: Process and intermediates for isopropyl 3S-amino-4-cyclohexyl-2R-hydroxybutyrate and 3S-amino-2R-hydroxy-5-methylhexanoate from R-malic acid. These products are of known utility in the synthesis of certain renin inhibitors.
    Type: Grant
    Filed: June 29, 1989
    Date of Patent: October 23, 1990
    Assignee: Pfizer Inc.
    Inventor: Robert W. Dugger