Abstract: A system for use in invasive medical procedures of the skin with a plastic clear tent like structure that is internally sterile and has incorporated gloves, attaches to the skin, and allows any devices contained in the system to be manipulated in sterile fashion to accomplish a number of different medical procedures while facilitating ultrasound guidance of procedures.

Abstract: The specification relates to compounds of Formula (1): and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cancer.

Abstract: An electric pushback vehicle includes a frame having a forward portion and a rear portion. The vehicle further includes front drive axle and a rear drive axle configured to communicate power to ground engaging members. A traction battery is housed within the electric pushback vehicle and provides electric power to an electric motor to drive an output shaft. A transmission is connected to receive mechanical power from the electric motor through a torque converter.

Abstract: Various aspects and embodiments are directed to a streamlined computer device and a graphical user interface that organizes interface elements into views of computer content for presentation to a user. Various views of digital media content permits users to easily and efficiently access various digital media content. Different views are used to provide an interface that is responsive to configurations of the device and responsive to activity being performed by the user. Aspects include permitting the user to maintain and manage digital media content libraries. According to some embodiments, the libraries comprise user digital media content and references digital media content. Functionality provided to a user can be tailored to the type of content displayed, accessed and/or managed. According to various aspects, methods and systems are provided for accessing and managing digital media libraries on a streamlined computing device with a plurality selectable I/O profiles.

Abstract: A method including detecting that a vehicle that may be propelled by an electric drive system having one or more motors disconnects or begins disconnecting from an off-board source of power while the one or more motors are being powered by the off-board source of power. The method may include supplanting a decreasing amount of a first electric energy supplied by the off-board source of power to the electric drive system with an amount of a second electric energy supplied by an onboard source of power to the electric drive system responsive to the detection of the disconnect from the off-board source of power.

Abstract: In exemplary embodiments, methods and systems are provided for downloading of geographic information. In accordance with an exemplary embodiment, a method is provided that includes the following steps: identifying, via a processor using map data, a plurality of geographic areas in which a vehicle is to travel along a selected route to a destination; identifying, via the processor using the map data, a plurality of map tiles corresponding to the plurality of geographic areas, such that each of the plurality of map tiles corresponds to a different one of the plurality of geographic areas; obtaining data access information for each of the plurality of geographic areas; and determining, via the processor, a prioritized sequence for downloading the plurality of map tiles, based on the data access information for the plurality of geographic areas.

Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry.

Abstract: The method to control cleanroom conditions, including zone particle concentration, occupancy status, and heating, ventilation, and air conditioning (HVAC) system conditions, includes detecting a zone particle concentration, an occupancy status, and HVAC system conditions. The cleanroom includes the HVAC system in communication with the zone of the cleanroom and with a computer processor as a control unit of the cleanroom. The zone particle concentration, the occupancy status, and the HVAC system conditions are communicated to the computer processor, and a desired zone particle concentration is determined based on a range of desired HVAC system conditions with model predictive control. A first control signal to the HVAC system based on the occupancy status, the zone particle concentration, and the desired zone particle concentration is determined. The first control signal is communicated to the HVAC system, and the HVAC system activates according to the first control signal.

Abstract: A weight system comprising a weight material assembly having predetermined dimensions and a container assembly. The weight material assembly comprises weight material comprising at least one of sand and gravel and a weight material bag adapted to contain the weight material. The weight material bag comprises at least a ply of paper material. The container assembly comprises a panel assembly defining an interior chamber, an access opening, and an access flap and a closure system operable in an open configuration and a closed configuration. The interior chamber is sized and dimensioned to accommodate the predetermined dimensions of the weight material assembly. The weight material assembly may be displaced through the access opening and into the interior chamber. With the weight material assembly arranged within the interior chamber, the panel assembly is configured in the closed position and the closure system is operated in the closed configuration.

Abstract: Presented herein are techniques to retain full resolution across all screens of a video wall and achieve perfect visual synchronization (sync), such that all screens in a video wall configuration act and look like a single screen. In one form, a system is provided that includes a plurality of displays being arranged in one or more adjacent vertical columns, and a plurality of media players. Each media player of the plurality of media players is coupled to a corresponding display of the plurality of displays and is configured to play out a corresponding positional subset of an overall media content, with a corresponding delay, to the corresponding display arranged in the one or more adjacent vertical columns to compensate for scan out lag associated with the media content.

Abstract: A weight system for containing fill material for supporting a free-standing object comprises a weight container defines an interior chamber and fill opening and a closure system. Fill material within the interior chamber is entirely below the fill opening.

Abstract: Systems and methods of in vivo and in vitro radical protein foot-printing using an opto-fluidic array are presented. These teachings may be used to, for example, study three-dimensional protein structure or bio-kinetics. Radical dosimetry including an optional intrinsic standard is used. Real-time feedback based on an internal standard provides comparability between different experiments and in vivo and in vitro analysis results in data that is representative of actual biological conditions.

Abstract: A planar (two-dimensional, XY location) touch sensor may include a knitted structure and supplementary method of sensing detects human touch on a fabric surface. This sensor may be fully knitted and detect the continuous planar location and contact force of human touch along the surface of the structure. The fabric may conform to any arbitrary surface and may be a rectangle for touch pad applications. This sensor may be used for applications that include robotics and human-machine interaction, smart garments and wearables, as well as medical textiles and flexible embedded sensors. This touch sensor may require as few as only two electrode connections from the fabric to sense both planar touch and pressure, which allows it to work in areas with limited space that allow for limited complexity for wiring.

Abstract: A weight system for containing fill material for supporting a free-standing object, comprising a container defining an interior chamber adapted to contain the fill material and a closure system. The closure system is arranged to allow the container to be configured in a closed configuration and an open configuration. Fill material is arranged within the interior chamber when the container is in the open configuration.

Abstract: Presented herein are techniques to retain full resolution across all screens of a video wall and achieve perfect visual synchronization (sync), such that all screens in a video wall configuration act and look like a single screen. In one form, a system is provided that includes a plurality of displays being arranged in one or more adjacent vertical columns, and a plurality of media players. Each media player of the plurality of media players is coupled to a corresponding display of the plurality of displays and is configured to play out a corresponding positional subset of an overall media content, with a corresponding delay, to the corresponding display arranged in the one or more adjacent vertical columns to compensate for scan out lag associated with the media content.

Abstract: A weight system comprising a weight material assembly having predetermined dimensions and a container assembly. The weight material assembly comprises weight material comprising at least one of sand and gravel and a weight material bag adapted to contain the weight material. The weight material bag comprises at least a ply of paper material. The container assembly comprises a panel assembly defining an interior chamber, an access opening, and an access flap and a closure system operable in an open configuration and a closed configuration. The interior chamber is sized and dimensioned to accommodate the predetermined dimensions of the weight material assembly. The weight material assembly may be displaced through the access opening and into the interior chamber. With the weight material assembly arranged within the interior chamber, the panel assembly is configured in the closed position and the closure system is operated in the closed configuration.

Abstract: Presented herein are techniques to retain full resolution across all screens of a video wall and achieve perfect visual synchronization (sync), such that all screens in a video wall configuration act and look like a single screen. In one form, a system is provided that includes a plurality of displays being arranged in one or more adjacent vertical columns, and a plurality of media players. Each media player of the plurality of media players is coupled to a corresponding display of the plurality of displays and is configured to play out a corresponding positional subset of an overall media content, with a corresponding delay, to the corresponding display arranged in the one or more adjacent vertical columns to compensate for scan out lag associated with the media content.

Abstract: A weight system for supporting a free-standing object comprising a weight material assembly and a container assembly. The container assembly comprises a panel assembly defining an interior chamber, an access opening, and an access flap and a closure system operable in an open configuration in which the access flap may be displaced between closed and open positions and a closed configuration in which the access flap is secured in the closed position. The interior chamber is sized and dimensioned to accommodate predetermined dimensions of the weight material assembly. The access opening is sized and dimensioned to allow the weight material assembly to be displaced through the access opening and into the interior chamber. The weight material assembly is arranged within the interior chamber with the panel assembly configured in the closed position and the closure system operated in the closed configuration.

Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry.

Abstract: A planar (two-dimensional, XY location) touch sensor may include a knitted structure and supplementary method of sensing detects human touch on a fabric surface. This sensor may be fully knitted and detect the continuous planar location and contact force of human touch along the surface of the structure. The fabric may conform to any arbitrary surface and may be a rectangle for touch pad applications. This sensor may be used for applications that include robotics and human-machine interaction, smart garments and wearables, as well as medical textiles and flexible embedded sensors. This touch sensor may require as few as only two electrode connections from the fabric to sense both planar touch and pressure, which allows it to work in areas with limited space that allow for limited complexity for wiring.