Abstract: The invention provides a compound of formula (1). or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: A system for collecting tissue samples, such as meat tissues on carcasses, for example in the food industry. Also provided are methods for collecting tissue samples, and to a non-transitory computer-readable medium comprising program instructions to execute at least one step of the method for collecting tissue samples.

Abstract: A unit dose glass cleaner concentrate product includes from 5 grams to 50 grams of a concentrated glass cleaning composition encased in a water soluble film. The concentrated glass cleaning composition includes at least one cleaning solvent and at least one surfactant. The total weight percentage of the cleaning solvents and surfactants, expressed on an anhydrous basis, is at least 50% of the weight of the unit dose window cleaner concentrate product. The unit dose glass cleaner concentrate product can be added to a container and diluted to produce a glass cleaning solution.

Abstract: The invention provides a hybrid bag which comprises a strap, a bag body, a lid, and a bag sleeve wherein the hybrid bag has a first configuration where the bag body houses the lid and the bag sleeve and a second configuration where the lid and the bag sleeve are extended from the bag body; wherein the bag body has one or more wheels; and wherein the bag sleeve is arranged between the bag body and the lid to form a container which may be accessed through the lid.

Abstract: In a dipole antenna, a capacitive coupling element is introduced in the form of a conductive strip and is placed in parallel with the dipole conductive strip of the dipole arm. To that end, the conductive strip of the capacitive element is formed on a first copper layer of the PCB in parallel to an extended conductive strip of a dipole arm, that is also disposed on the first copper layer of the PCB. The conductive strip of the capacitive element extends horizontally from the center of the dipole arm in an equal distant on each side. A capacitive plate is placed on the second copper layer of the PCB on the opposite side of the first copper layer and is coupled to the conductive strip of the capacitive element via a plated through hole. The capacitive plate placed on the second copper layer extends downwardly so that a portion of it overlaps with the dipole conductive strip located on the first copper layer forming the capacitance coupling element.

Abstract: An article includes a unit dose packet of a concentrated cleaning composition for cleaning laundry. The concentrated cleaning composition comprising a nonionic surfactant, fatty acid methyl ester sulfonate, fatty acid soap, one or a plurality of enzymes, and a solvent system. The cleaning composition is compatible with polyvinyl alcohol film. The unit dose packet includes the concentrated laundry cleaning composition disposed in a single chamber, dual chamber, or multi-chamber unit dose packet having a total weight of the concentrated cleaning composition of from 15 grams to 30 grams.

Abstract: A controlled release pharmaceutical composition for eye injection for ophthalmic care. The composition comprises at least one active pharmaceutical ingredient and at least one biocompatible polymer and at least one biocompatible solvent. The composition, which is capable of forming an in-situ implant composition, comprises an injectable solution, suspension, emulsion or dispersion. The formulation can be injected through a needle that is suitable in size for an eye injection. The present compositions can be used for treatment of ophthalmic conditions, including glaucoma, dry and wet age-related macular degeneration, diabetic retinopathy, dry eye syndrome, and uveitis.

Abstract: A multi-compartment walk-in bathtub is disclosed that allows for a first compartment of the walk-in bathtub to be filled with a quantity of water while a second compartment of the walk-in bathtub allows the user to enter the bathtub. A first movable gate contains a volume of water in the first compartment while the second compartment is in an unfilled condition. A second movable gate is operable to open and close an entry sidewall of the bathtub, allowing the user to enter the second compartment. The second movable gate is then moved to a closed position. When the second movable gate is in the closed condition, the first movable gate may be moved to an open condition to release the volume of water and fill the walk-in bathtub to a filled condition. A seat may be provided that is selectively elevated and lowered by drive mechanism.

Abstract: Described herein are examples of a system, composed of a unique combination and/or customization of subsystems, components and methods of measuring detecting, isolating, and analyzing continuous and intermittent electromechanical failures in vehicle electronics interconnections equipment by applying relevant environmental forces to replicate operational stressors on electronics interconnection equipment to rigorously and exhaustively reproduce failures as if in operational use so that they may be identified, located, and repaired. As environmental stressors are applied, testing failure data is produced by measuring variances of expected voltages across conductive paths, with or without components, of the electromechanical equipment. The system produces comprehensive analyses, reports on all failure indications supported by heuristics, and statistics and applies machine learning techniques of each failure of each serial numbered UUT over time to improve the operational reliability of systems.

Abstract: The invention relates to powder coating compositions suitable for low temperature powder coating crosslinking typically at curing temperature is between 75 and 140° C. which can be used for powder coating temperature-sensitive substrates like MDF, wood, plastic or temperature sensitive metal alloys.

Abstract: An apparatus powered by batteries may include a first processor and a second processor. The first processor may consume more electrical power than the second processor. The second processor acquires data from one or more sensors. At a predetermined time or other trigger, the second processor activates the first processor that is then used to send the acquired data to an external device. For example, items are stowed on the apparatus that includes weight sensors. The second processor awakens hourly, acquires weight data indicative of the weight of items stowed on the apparatus, and returns to a sleep mode. After 24 hours of acquiring weight data, the second processor activates the first processor to send the accumulated weight data to an external device, such as a server, using a network interface. Power consumption is substantially reduced, allowing the apparatus to operate without external power for extended periods of times.

Abstract: A controlled release pharmaceutical composition for eye injection for ophthalmic care. The composition comprises at least one active pharmaceutical ingredient and at least one biocompatible polymer and at least one biocompatible solvent. The composition, which is capable of forming an in-situ implant composition, comprises an injectable solution, suspension, emulsion or dispersion. The formulation can be injected through a needle that is suitable in size for an eye injection. The present compositions can be used for treatment of ophthalmic conditions, including glaucoma, dry and wet age-related macular degeneration, diabetic retinopathy, dry eye syndrome, and uveitis.

Abstract: The invention relates to powder coating compositions suitable for low temperature powder coating crosslinking typically at curing temperature is between 75 and 140° C. which can be used for powder coating temperature-sensitive substrates like MDF, wood, plastic or temperature sensitive metal alloys.

Abstract: A first device is configured to establish a connection over a short-range communication link with a second device. The first device may transition to a sleep state, terminate (i) a paging operation and a page scanning operation associated with a paging protocol and (ii) an advertisement scanning operation associated with an advertisement protocol and perform an advertisement broadcast operation associated with the advertisement protocol, the advertisement broadcast operation generating an advertisement to be broadcast at a first interval, wherein the first interval is greater than a second interval for performing advertisement broadcast operations in an active state.

Abstract: A system for electrode dressing including a cutter with a rim and a center land supported on the rim by a number of flutes defining openings between the flutes. The flutes and the center land define a cutting profile of the cutter. The cutter is configured to rotate about an axis passing through the center land. Cutting edges are disposed on the flutes and are made of a first material having a Vickers hardness (HV) of at least 850 HV, overlaid by a second material having a Vickers hardness of at least 3200 HV. The cutter profile comprises a face cutting profile extending radially outward from the axis that is disposed at an angle of less than six-degrees relative to a radial normal of the cutter.

Abstract: A first device is configured to establish a connection over a short-range communication link with a second device. The first device may transition to a sleep state, terminate (i) a paging operation and a page scanning operation associated with a paging protocol and (ii) an advertisement scanning operation associated with an advertisement protocol and perform an advertisement broadcast operation associated with the advertisement protocol, the advertisement broadcast operation generating an advertisement to be broadcast at a first interval, wherein the first interval is greater than a second interval for performing advertisement broadcast operations in an active state.