Abstract: Systems and methods of a safety helmet for protecting the human head against repetitive impacts, moderate impacts and severe impacts so as to significantly reduce the likelihood of both translational and rotational brain injury and concussions may be provided. The helmet may include an outer shell, an outer liner disposed within and coupled to the outer shell, and an inner liner disposed within and coupled in spaced opposition to the outer liner. A damper array may allow for omnidirectional movement of the inner liner relative to the outer liner and the outer shell.

Abstract: Systems and methods of a safety helmet for protecting the human head against repetitive impacts, moderate impacts and severe impacts so as to significantly reduce the likelihood of both translational and rotational brain injury and concussions may be provided. The helmet may include an outer shell, an outer liner disposed within and coupled to the outer shell, and an inner liner disposed within and coupled in spaced opposition to the outer liner. A damper array may allow for omnidirectional movement of the inner liner relative to the outer liner and the outer shell.

Abstract: Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region

Abstract: A query may be determined based on data retrieval parameter values. The data retrieval parameter values may include a data type parameter identifying a designated data type of a plurality of data types corresponding with database observability data generated during operation of a database system. The of data retrieval parameter values may also include a designated time period during which to retrieve data associated with the designated data type. A query may be determined based on the plurality of data retrieval parameter values via a collection manager in a database application layer associated with the database system. The query may be executed to retrieve a designated dataset of database observability data corresponding with the designated data type and generated by the database system during the designated time period.

Abstract: Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region

Abstract: A handheld medical device with a distal implement is disclosed. The handheld rotary medical device may include an inner drive shaft, an elongated, tubular, outer housing encapsulating the inner drive shaft such that the inner drive shaft is positioned within the outer housing. The inner drive shaft may include one or more inner drive shaft bendable sections, and the outer housing may include one or more outer housing bendable sections. The inner drive shaft bendable section may be heated to anneal the material forming the inner drive shaft bendable section such that during use the inner drive shaft bendable section may be bent into a desired position and, once bent, the inner drive shaft bendable section remains in the desired position and does not bind against the elongated, tubular, outer housing.

Abstract: Mapping of database partitions to available nodes. Metric information related to the partitions of the database are stored. One or more metrics associated with the partitions are gathered. A plurality of potential mappings of partitions to nodes are evaluated. One of the potential mappings of partitions to nodes to result in improved metric distribution among the nodes and the partition moves are within a pre-selected move constraint is selected. The selected potential mapping is implemented by moving one or more partitions between one or more nodes.

Abstract: A query may be determined based on data retrieval parameter values. The data retrieval parameter values may include a data type parameter identifying a designated data type of a plurality of data types corresponding with database observability data generated during operation of a database system. The of data retrieval parameter values may also include a designated time period during which to retrieve data associated with the designated data type. A query may be determined based on the plurality of data retrieval parameter values via a collection manager in a database application layer associated with the database system. The query may be executed to retrieve a designated dataset of database observability data corresponding with the designated data type and generated by the database system during the designated time period.

Abstract: A handheld medical device with a distal implement is disclosed. The handheld rotary medical device may include an inner drive shaft, an elongated, tubular, outer housing encapsulating the inner drive shaft such that the inner drive shaft is positioned within the outer housing. The inner drive shaft may include one or more inner drive shaft bendable sections, and the outer housing may include one or more outer housing bendable sections. The inner drive shaft bendable section may be heated to anneal the material forming the inner drive shaft bendable section such that during use the inner drive shaft bendable section may be bent into a desired position and, once bent, the inner drive shaft bendable section remains in the desired position and does not bind against the elongated, tubular, outer housing.

Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.

Abstract: Systems and methods of a safety helmet for protecting the human head against repetitive impacts, moderate impacts and severe impacts so as to significantly reduce the likelihood of both translational and rotational brain injury and concussions can be provided. The helmet can include an outer shell, an outer liner disposed within and coupled to the outer shell, and an inner liner disposed within and coupled in spaced opposition to the outer liner. A polymer liner can be coupled to the inner liner and can at least partly separate the outer liner and the inner liner. Pads and dampers can also couple the outer liner and inner liner and provide for and control omnidirectional movement of the liners relative to each other.

Abstract: Systems and methods are provided herein for rapid detection, separation, purification, and quantification of viral particles in a sample. According to some embodiments, a microfluidic device is provided for receiving the sample which may contain viral particles. An electrode of the microfluidic device may be used to generate dielectrophoretic (DEP) and/or electroosmotic (EO) forces acting on the sample. The applied DEP and/or EO forces may immobilize components of the sample on the surface of the electrode, may aggregate viral particles of the sample in one region of the microfluidic device, and may separate other components of the sample from the viral particles. The techniques may be performed rapidly, for example, in eight hours or less, and may not affect infectivity of the viral particles. In some embodiments, the sample may be labeled to enhance a response of one or more of the sample components to the DEP and/or EO forces.

Abstract: Systems and methods of a safety helmet for protecting the human head against repetitive impacts, moderate impacts and severe impacts so as to significantly reduce the likelihood of both translational and rotational brain injury and concussions may be provided. The helmet may include an outer shell, an outer liner disposed within and coupled to the outer shell, and an inner liner disposed within and coupled in spaced opposition to the outer liner. A damper array may allow for omnidirectional movement of the inner liner relative to the outer liner and the outer shell.

Abstract: The disclosure generally relates to methods and applications of single-cell barcoding and methods of nucleotide sequencing using composition comprising lipid-modified oligonucleotides.

Abstract: Systems and methods of a safety helmet for protecting the human head against repetitive impacts, moderate impacts and severe impacts so as to significantly reduce the likelihood of both translational and rotational brain injury and concussions can be provided. The helmet can include an outer shell, an omnidirectional liner disposed within and coupled to the outer shell and configured to move relative to the outer shell, and a chinstrap coupled to the omnidirectional liner. The chinstrap coupled to the omnidirectional liner can hold a wearer's head to the omnidirectional liner and prevent the chinstrap from applying forces to the wearer while omnidirectional liner moves relative to outer shell. Other embodiments may include a chinguard with a movable chincup.

Abstract: A handheld medical device with a distal implement is disclosed. The handheld rotary medical device may include an inner drive shaft, an elongated, tubular, outer housing encapsulating the inner drive shaft such that the inner drive shaft is positioned within the outer housing. The inner drive shaft may include one or more inner drive shaft bendable sections, and the outer housing may include one or more outer housing bendable sections. The inner drive shaft bendable section may be heated to anneal the material forming the inner drive shaft bendable section such that during use the inner drive shaft bendable section may be bent into a desired position and, once bent, the inner drive shaft bendable section remains in the desired position and does not bind against the elongated, tubular, outer housing.

Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.

Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.

Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.

Abstract: Methods and apparatus for detecting, quantifying, enriching, and/or separating bacterial species in fluid sample are provided. The fluid sample is provided as input to a microfluidic passage of a microfluidic device, wherein the microfluidic device comprises at least one electrode disposed adjacent to the microfluidic passage. The at least one electrode is activated to capture bacteria in the sample using dielectrophoresis, wherein the capture efficiency of bacteria is at least 99%.