Abstract: Computer based methods and systems for evaluating different building designs are disclosed. In one embodiment, the method involves generating a first set of different building massing configurations using a shape grammar, storing the generated first set of different building massing configurations in a building massing library, reducing the first set of different building massing configurations according to a parameter search to form a second set of different building massing configurations, the second set being a subset of the first set, and using the second set of different building massing configurations to evaluate an aspect of a building system.

Abstract: A cooling system for a hybrid powertrain of a motor vehicle comprising an internal combustion engine and an electric traction assembly, comprising a main circuit that can be traversed by a coolant in order to cool the internal combustion engine to a first temperature level and a secondary circuit that can be traversed by a coolant to cool the electric traction assembly to a second temperature level, lower than the first level, each of the circuits and comprising a radiator capable of cooling the coolant by means of heat exchange with an air flow, at least one hydraulic pump for circulating the coolant in the coolant circuits, and one electronic control unit capable of controlling the hydraulic pumps. The control unit comprises a module for recovering information on the dynamics of the vehicle and a module for controlling the flow from the hydraulic pumps on the basis of that information.

Abstract: A cooling system for a hybrid powertrain of a motor vehicle comprising an internal combustion engine and an electric traction assembly, comprising a main circuit that can be traversed by a coolant in order to cool the internal combustion engine to a first temperature level and a secondary circuit that can be traversed by a coolant to cool the electric traction assembly to a second temperature level, lower than the first level, each of the circuits and comprising a radiator capable of cooling the coolant by means of heat exchange with an air flow, at least one hydraulic pump for circulating the coolant in the coolant circuits, and one electronic control unit capable of controlling the hydraulic pumps. The control unit comprises a module for recovering information on the dynamics of the vehicle and a module for controlling the flow from the hydraulic pumps on the basis of that information.

Abstract: Compositions and methods relating to interfering with the interaction of gangliosides, such as GM1, with their ligands are provided. For example, methods are provided for treating infections by blocking the infectious agent from binding with GM1 using GM1-like peptides. Also provided are methods of inhibiting ligands from binding to GM1 on the surface of cells and for neutralizing anti-GM1 antibodies in neurological diseases.

Abstract: In some aspects, the disclosure is directed to methods and systems for driving demand for services. An appointment platform operating on a server may identify, based on an appointment inventory of a service provider, an open appointment to be filled. The appointment platform may rank a plurality of users to which the open appointment may be offered. The appointment platform may rank a user of the plurality of users based on a current membership score of the user. The appointment platform may determine, based on the ranking, to offer the user the open appointment. The appointment platform may identify, based on the current membership score of the user, a type of incentive from a plurality of types of incentives, to offer to the user for filling the open appointment.

Abstract: Computer based methods and systems for characterizing the energy use of multiple different building massing configurations are disclosed. In one embodiment, a computer based method involves specifying a set of parameters for a building massing configuration, calculating a normalized energy use index for multiple different building massing configurations that meet the specified set of parameters, wherein the normalized energy use index for each of the multiple different building massing configurations is normalized against a reference energy use index of a reference building, ranking the multiple different building massing configurations by the respective normalized energy use indexes, and selecting at least one of the different massing configurations for display on a graphical user interface according to the ranking.

Abstract: An automobile including an electric motor, a passenger compartment, an electronic power circuit, and a cooling circuit for the electronic power circuit, in which a coolant flows and which includes: a heat exchanger configured to discharge calories carried by the coolant to outside of the vehicle; a heating radiator provided upstream from the exchanger and configured to transfer the calories carried by the coolant to air in the passenger compartment; and an adiabatic tank configured to store at least a fraction of the coolant flowing in the cooling circuit.

Abstract: A device for cooling a battery or batteries of a motor vehicle, for example an electric vehicle, includes a temperature regulating unit including an evaporator that is used to cool the passenger compartment of the vehicle and arranged in a housing, the battery or batteries being contained in a case. The housing of the evaporator is connected to a conduit, an outlet of which is oriented towards a heat exchange area on at least one outer surface of the case containing the battery or batteries.

Abstract: Disclosed are compositions and methods for treating Guillain-Barré syndrome (GBS) in a subject that involves neutralizing specific pathogenic anti-glycolipid antibodies in the circulation of the subject. This can involve administering to the subject a molecular mimic of a ganglioside that serves as a specific competitive inhibitor for anti-ganglioside antibodies in the circulation. Also disclosed is an animal model of GBS having anti-ganglioside antibodies in the circulation.

Abstract: Compositions and methods relating to interfering with the interaction of gangliosides, such as GM1, with their ligands are provided. For example, methods are provided for treating infections by blocking the infectious agent from binding with GM1 using GM1-like peptides. Also provided are methods of inhibiting ligands from binding to GM 1 on the surface of cells and for neutralizing anti-GM1 antibodies in neurological diseases.

Abstract: Disclosed are compositions and methods for treating Guillain-Barré syndrome (GBS) in a subject that involves neutralizing specific pathogenic anti-glycolipid antibodies in the circulation of the subject. This can involve administering to the subject a molecular mimic of a ganglioside that serves as a specific competitive inhibitor for anti-ganglioside antibodies in the circulation. Also disclosed is an animal model of GBS having anti-ganglioside antibodies in the circulation.

Abstract: Disclosed are compositions and methods for treating Guillain-Barré syndrome (GBS) in a subject that involves neutralizing specific pathogenic anti-glycolipid antibodies in the circulation of the subject. This can involve administering to the subject a molecular mimic of a ganglioside that serves as a specific competitive inhibitor for anti-ganglioside antibodies in the circulation. Also disclosed is an animal model of GBS having anti-ganglioside antibodies in the circulation.

Abstract: A system for overall control of heat for a passenger compartment and for electrical units in a motor vehicle that is completely or partially propelled by an electric engine powered by a battery, including a heat-control fluid circuit coupled to a heating device and/or to a cooling device enabling the fluid to store calories or frigories when the system is plugged into an electrical network outside of the vehicle. The fluid circuit is capable of releasing calories and/or frigories to the air of the passenger compartment, in an alternating manner, either through a heat exchanger between the circuit and the air of the passenger compartment, or using a climate circuit forming a heat pump and/or an air-conditioning system.

Abstract: A method for controlling a vehicle drive train, which communicates or maintains in communication via at least one valve two cooling circuits operating normally and respectively associated with a heat engine and with at least one electrical member.

Abstract: A device for cooling a battery or batteries of a motor vehicle, for example an electric vehicle, includes a temperature regulating unit including an evaporator that is used to cool the passenger compartment of the vehicle and arranged in a housing, the battery or batteries being contained in a case. The housing of the evaporator is connected to a conduit, an outlet of which is oriented towards a heat exchange area on at least one outer surface of the case containing the battery or batteries.

Abstract: An automobile including an electric motor, a passenger compartment, an electronic power circuit, and a cooling circuit for the electronic power circuit, in which a coolant flows and which includes: a heat exchanger configured to discharge calories carried by the coolant to outside of the vehicle; a heating radiator provided upstream from the exchanger and configured to transfer the calories carried by the coolant to air in the passenger compartment; and an adiabatic tank configured to store at least a fraction of the coolant flowing in the cooling circuit.

Abstract: Disclosed are compositions and methods for treating Guillain-Barré syndrome (GBS) in a subject that involves neutralizing specific pathogenic anti-glycolipid antibodies in the circulation of the subject. This can involve administering to the subject a molecular mimic of a ganglioside that serves as a specific competitive inhibitor for anti-ganglioside antibodies in the circulation. Also disclosed is an animal model of GBS having anti-ganglioside antibodies in the circulation.

Abstract: A system for determining memory addresses including a first content-addressable memory (CAM) configured to generate a first matchvector based on a first key; a first inverse-mask-reverse (IMR) module operatively connected to the first CAM, where the first IMR module is configured to generate a first auxiliary matchvector based on the first matchvector; and a first priority encoder (PE) operatively connected to the first IMR module, where the first PE is configured to output a first encoded memory address based on the first auxiliary matchvector, where the first CAM, the first IMR module, and the first PE are associated with a first reconfigurable content-addressable memory (RCAM).