Patents by Inventor Robin Alec Fairhurst

Robin Alec Fairhurst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BETA2-ADRENOCEPTOR AGONISTS
    Publication number: 20140343091
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Application
    Filed: August 4, 2014
    Publication date: November 20, 2014
    Applicant: NOVARTIS AG
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • Oxazolidin-2-one compounds and uses thereof
    Patent number: 8865894
    Abstract: The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: October 21, 2014
    Assignee: Novartis AG
    Inventors: Giorgio Caravatti, Robin Alec Fairhurst, Pascal Furet, Frédéric Stauffer, Frank Hans Seiler, Clive McCarthy, Heinrich Rueeger
  • Beta2-adrenoreceptor agonists
    Patent number: 8796307
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: August 5, 2014
    Assignee: Novartis AG
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • PYRROLIDINE-1,2-DICARBOXAMIDE DERIVATIVES
    Publication number: 20140186469
    Abstract: The present invention relates to a compound of formula (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.
    Type: Application
    Filed: February 27, 2014
    Publication date: July 3, 2014
    Applicant: NOVARTIS AG
    Inventors: Robin Alec Fairhurst, Vito Guagnano, Patricia Imbach-Weese, Giorgio Caravatti, Pascal Furet
  • Oxazolidin-2-one-Pyrimidine Derivatives
    Publication number: 20140135330
    Abstract: The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 15, 2014
    Applicant: NOVARTIS AG
    Inventors: Robin Alec Fairhurst, Pascal Furet, Frank Stephan Kalthoff, Andreas Lerchner, Heinrich Rueeger
  • Pyrrolidine-1,2-dicarboxamide derivatives
    Patent number: 8710085
    Abstract: The present invention relates to a compound of formula (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: April 29, 2014
    Assignee: Novartis AG
    Inventors: Vito Guagnano, Robin Alec Fairhurst, Patricia Imbach-Weese, Giorgio Caravatti, Pascal Furet
  • Beta2-Adrenoreceptor Agonists
    Publication number: 20140066478
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways disease.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 6, 2014
    Applicant: Novartis AG
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • BETA2-adrenoreceptor agonists
    Patent number: 8658673
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: February 25, 2014
    Assignee: Novartis AG
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • PYRROLIDINE-1,2-DICARBOXAMIDE DERIVATIVES
    Publication number: 20140005232
    Abstract: The present invention relates to a compound of formula (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameliorated by inhibition of phosphatidylinositol 3-kinase.
    Type: Application
    Filed: May 24, 2013
    Publication date: January 2, 2014
    Applicant: NOVARTIS AG
    Inventors: Robin Alec Fairhurst, Vito Guagnano, Patricia Imbach-Weese, Giorgio Caravatti, Pascal Furet
  • FLUOROPHENYL BICYCLIC HETEROARYL COMPOUNDS
    Publication number: 20130338152
    Abstract: The present invention provides a compound the invention, and its use as a IGF-1R inhibitor. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: March 8, 2012
    Publication date: December 19, 2013
    Applicants: IRM LLC, NOVARTIS AG
    Inventors: Bei Chen, Robin Alec Fairhurst, Songchun Jiang, Wenshuo Lu, Thomas H. Marsilje, III, Clive McCarthy, Pierre-Yves Michellys, Stefan Stutz
  • BENZOTHIAZOLONE COMPOUND
    Publication number: 20130245080
    Abstract: The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.
    Type: Application
    Filed: September 5, 2012
    Publication date: September 19, 2013
    Applicant: NOVARTIS AG
    Inventors: Jun CAO, Bernhard ERB, Robin Alec FAIRHURST, Arnaud GRANDEURY, Shinji HATAKEYAMA, Magdalena KOZICZAK-HOLBRO, Xinzhong LAI, Philipp LUSTENBERGER, Bernd RIEBESEHL, Nicola TUFILLI, Thomas ULLRICH, Xiang WU, Jianguang ZHOU
  • BETA2-ADRENORECEPTOR AGONISTS
    Publication number: 20130231367
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Application
    Filed: April 8, 2013
    Publication date: September 5, 2013
    Applicant: Novartis AG
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • Pyrrolidine-1,2-dicarboxamide derivatives
    Patent number: 8476268
    Abstract: The present invention relates to a compound of formula (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: July 2, 2013
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Vito Guagnano, Patricia Imbach-Weese, Giorgio Caravatti, Pascal Furet
  • Beta-2-adrenoreceptor agonists
    Patent number: 8436017
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: May 7, 2013
    Assignee: Novartis AG
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • 2-carboxamide cycloamino ureas
    Patent number: 8357707
    Abstract: The present invention relates to compounds of formula I and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameliorated by inhibition of phosphatidylinositol 3-kinase.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: January 22, 2013
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Marc Gerspacher, Robert Mah
  • beta-2-Adrenoreceptor Agonists
    Publication number: 20120302531
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Application
    Filed: July 23, 2012
    Publication date: November 29, 2012
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • Organic compounds
    Patent number: 8318750
    Abstract: A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: November 27, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor, Brian Cox
  • Organic compounds 75074
    Patent number: 8318935
    Abstract: A compound of formula (I), or tautomers, or stereoisomers, or solvates, or pharmaceutically acceptable salts thereof, wherein M1, M2, L1, L2, W1, W2, X1, X2, Y1, Y2, A, R5 and R5a are as defined herein for the for treatment of conditions treatable by the blockade of an epithelial sodium channel, particularly conditions benefiting from mucosal hydration.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: November 27, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Rebecca Butler, Paul Oakley, Stephen Paul Collingwood, Nichola Smith, Emily Stanley, Maria Ines Rodriguez Perez
  • Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls
    Publication number: 20120289501
    Abstract: The invention relates to new derivatives of formula I, wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of a proliferative disease.
    Type: Application
    Filed: November 23, 2010
    Publication date: November 15, 2012
    Applicant: NOVARTIS AG
    Inventors: Bei Chen, Robin Alec Fairhurst, Andreas Floersheimer, Pascal Furet, Songchun Jiang, Wenshuo Lu, Thomas H. Marsilje, III, Andrea Vaupel
  • Substituted 2-carboxamide cycloamino ureas
    Patent number: 8293753
    Abstract: The present invention relates to compounds of formula I and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameliorated by inhibition of phosphatidylinositol 3-kinase.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: October 23, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Pascal Furet, Marc Gerspacher, Robert Mah