Patents by Inventor Robin Alec Fairhurst

Robin Alec Fairhurst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLIDINE-1,2-DICARBOXAMIDE DERIVATIVES
    Publication number: 20120263712
    Abstract: The present invention relates to a compound of formula (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.
    Type: Application
    Filed: June 5, 2012
    Publication date: October 18, 2012
    Applicant: NOVARTIS AG
    Inventors: Robin Alec FAIRHURST, Vito GUAGNANO, Patricia IMBACH, Giorgio CARAVATTI, Pascal FURET
  • Organic compounds
    Patent number: 8258141
    Abstract: A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: September 4, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor, Brian Cox
  • Pyrrolidine-1,2-dicarboxamide derivatives
    Patent number: 8227462
    Abstract: The present invention relates to a compound of formula (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: July 24, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Vito Guagnano, Patricia Imbach, Giorgio Caravatti, Pascal Furet
  • ETHER DERIVATIVES OF BICYCLIC HETEROARYLS
    Publication number: 20120165310
    Abstract: The invention relates to compounds of formula I, wherein the substituents are as defined in the specification; to processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; such compounds as a medicament; such compounds for the treatment of a proliferative disease.
    Type: Application
    Filed: September 10, 2010
    Publication date: June 28, 2012
    Applicant: NOVARTIS AG
    Inventors: Bei Chen, Robin Alec Fairhurst, Andreas Floersheimer, Pascal Furet, Vito Guagnano, Jiang Songchun, Wenshuo Lu, Thomas H. Marsilje, III, Clive McCarthy, Pierre-Yves Michellys, Frederic Stauffer, Stefan Stutz, Andrea Vaupel
  • Organic compounds
    Patent number: 8193164
    Abstract: A compound of formula (I), or stereoisomers or pharmaceutically acceptable salts thereof, wherein, R1a, R1b, R2a, R2b, U1, U2, X1, X2 and L are as defined herein.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: June 5, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor
  • Adenosine derivatives as A2A receptor agonists
    Patent number: 8188100
    Abstract: A compound of formula (I), or stereoisomers or pharmaceutically acceptable salts thereof, formula (1), or stereoisomers or pharmaceutically acceptable salts thereof, wherein A, U1, U2, R1a, R1b, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: May 29, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor
  • Mixtures or Organic Compounds for the Treatment of Airway Diseases
    Publication number: 20120108555
    Abstract: A medicament comprising, separately or together, (A) a compound of formula (I) in free or pharmaceutically acceptable salt or solvate form and (B) a corticosteroid, for simultaneous, sequential or separate administration in the treatment of an inflammatory or obstructive airways disease, the molar ratio of (A) to (B) being from 100:1 to 1:300.
    Type: Application
    Filed: January 9, 2012
    Publication date: May 3, 2012
    Inventors: Bernard Cuenoud, Robin Alec Fairhurst, Nicholas Lowther
  • Purine derivatives for use as adenosine A-2A receptor agonists
    Patent number: 8163754
    Abstract: Compounds of formula I in free or salt form, wherein R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: April 24, 2012
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor, Harinder Pal Singh
  • Beta-2-Adrenoreceptor Agonists
    Publication number: 20120077838
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 29, 2012
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • 5-HYDROXY-BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY
    Publication number: 20120041041
    Abstract: Compounds of formula (I) in free or salt or solvate form, wherein T has the meaning as indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the ?2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Application
    Filed: October 21, 2011
    Publication date: February 16, 2012
    Inventor: Robin Alec FAIRHURST
  • ORGANIC COMPOUNDS
    Publication number: 20120004212
    Abstract: A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.
    Type: Application
    Filed: August 26, 2011
    Publication date: January 5, 2012
    Inventors: Robin Alec Fairhurst, Roger John Taylor, Brian Cox
  • ORGANIC COMPOUNDS
    Publication number: 20120004247
    Abstract: A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.
    Type: Application
    Filed: August 26, 2011
    Publication date: January 5, 2012
    Inventors: Robin Alec Fairhurst, Roger John Taylor, Brian Cox
  • Purine derivatives as a2a agonists
    Patent number: 8071565
    Abstract: Compounds of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein W, R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: December 6, 2011
    Assignee: Novartis AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor
  • Pyrimidine derivatives as alk-5 inhibitors
    Patent number: 7989458
    Abstract: Compounds of formula (I) in free or salt or solvate form, where T1, T2, Ra and Rb have the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, liver fibrosis, muscle diseases and systemic skeletal disorders. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: August 2, 2011
    Assignee: Novartis AG
    Inventors: Catherine Leblanc, Maude Nadine Pierrette Pipet, Robin Alec Fairhurst, Claire Adcock, Robert Alexander Pulz, Duncan Shaw, Nikolaus Johannes Stiefl
  • Beta-2-Adrenoreceptor Agonists
    Publication number: 20110034509
    Abstract: Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
    Type: Application
    Filed: September 20, 2010
    Publication date: February 10, 2011
    Inventors: Bernard Cuenoud, Ian Bruce, Robin Alec Fairhurst, David Beattie
  • 2-Carboxamide Cycloamino Ureas
    Publication number: 20110003786
    Abstract: The present invention relates to compounds of formula I and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.
    Type: Application
    Filed: July 2, 2010
    Publication date: January 6, 2011
    Inventors: Robin Alec FAIRHURST, Marc GERSPACHER, Robert MAH
  • Substituted 2-Carboxamide Cycloamino Ureas
    Publication number: 20110003818
    Abstract: The present invention relates to compounds of formula I and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameliorated by inhibition of phosphatidylinositol 3-kinase.
    Type: Application
    Filed: June 28, 2010
    Publication date: January 6, 2011
    Inventors: Robin Alec Fairhurst, Pascal Furet, Marc Gerspacher, Robert Mah
  • Organic Compounds
    Publication number: 20100298286
    Abstract: The present invention relates to a compound of formula I and its salts, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameliorated by inhibition of phosphatidylinositol 3-kinase.
    Type: Application
    Filed: December 18, 2008
    Publication date: November 25, 2010
    Inventors: Robin Alec Fairhurst, Patricia Imbach
  • Organic Compounds
    Publication number: 20100286126
    Abstract: A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.
    Type: Application
    Filed: April 19, 2007
    Publication date: November 11, 2010
    Applicant: NOVARTIS AG
    Inventors: Robin Alec Fairhurst, Roger John Taylor, Brian Cox
  • Purine derivatives as a2a agonists
    Publication number: 20100240680
    Abstract: Compounds of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein W, R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
    Type: Application
    Filed: July 11, 2007
    Publication date: September 23, 2010
    Inventors: Robin Alec Fairhurst, Roger John Taylor