Patents by Inventor Roderick Alan Porter

Roderick Alan Porter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100216837
    Abstract: The present invention relates to compounds of formula (I), or salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 21, 2005
    Publication date: August 26, 2010
    Applicant: GLAXO GROUP LIMITED
    Inventors: Andrea Bozzoli, Daniel Marcus Bradley, Steven Coulton, Martin Leonard Gilpin, Jacqueline Anne MacRitchie, Roderick Alan Porter, Kevin Michael Thewlis
  • Patent number: 7745642
    Abstract: The present invention relates to compounds of formula (I), or to salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: June 29, 2010
    Assignee: Glaxo Group Limited
    Inventors: Daniel Marcus Bradley, Roderick Alan Porter
  • Patent number: 7741329
    Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: wherein the substituent variables are as defined herein, and their use as pharmaceuticals.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: June 22, 2010
    Assignee: SmithKline Beecham Limited
    Inventors: Clive Leslie Branch, Steven Coulton, Amanda Johns, Christopher Norbert Johnson, Roderick Alan Porter, Geoffrey Stemp, Kevin Thewlis
  • Publication number: 20100137428
    Abstract: The present invention relates to compounds of formula (I), or salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 3, 2010
    Inventors: Andrea Bozzoli, Clive Leslie Branch, Jacqueline Anne MacRitchie, Howard Robert Marshall, Roderick Alan Porter, Simone Spada
  • Publication number: 20100113545
    Abstract: Compounds of formula (I) or a salt thereof are provided: wherein R1, R2, R3, R4, R5, R6, R15, R7, R8 and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: January 30, 2008
    Publication date: May 6, 2010
    Inventors: Steven Coulton, Roderick Alan Porter
  • Publication number: 20100105713
    Abstract: Compounds of formula (I) or a salt thereof are provided: wherein R6, R7, R9, R10, R11, X, n, p, Ar and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further discloses pharmaceutical compositions and combinations comprising the compounds.
    Type: Application
    Filed: January 30, 2008
    Publication date: April 29, 2010
    Applicants: GLAXO GROUP LIMITED, UNIVERSITY OF NOTTINGHAM
    Inventors: Nadia Mamoona Ahmad, Daniele Andereotti, Justine Yeun Quai Lai, Howard Robert Marshall, David John Nash, Roderick Alan Porter
  • Publication number: 20100029700
    Abstract: Novel acetophenone compounds of formula (I), compositions containing (I), processes for the preparation of (I), and use of (I) as inhibitors of the glycine transporter, are provided. Definitions of Ar, R5, R6, R7, R8 and n are provided in the specification.
    Type: Application
    Filed: April 10, 2007
    Publication date: February 4, 2010
    Inventors: Clive Leslie Branch, Howard Marshall, David John Nash, Roderick Alan Porter
  • Publication number: 20100016374
    Abstract: Compounds of formula (I) and salts and solvates are provided: wherein R2 is selected from phenyl substituted with n R1 groups, and pyridyl substituted with n R1 groups; n=0, 1 or 2; each R1 is independently selected from the group consisting of halo, C1-4alkyl, C1-4alkoxy, haloC1-4alkyl, haloC1-4alkoxy and cyano; R3 is selected from hydrogen and C1-2 alkyl; R4 is selected from the group consisting of ethyl, n-propyl, i-propyl, n-butyl, i-butyl and t-butyl; or R3 and R4 together with the nitrogen atom to which they are attached form a saturated 5- or 6-membered heterocyclic ring optionally substituted with one or more groups X; each X is independently selected from the group consisting of C1-4alkyl, and haloC1-4alkyl; R12 is selected from the group consisting of hydrogen, fluoro, chloro, bromo, methyl and methylthio; R13 is selected from hydrogen, chloro and trifluoromethyl; R14 is selected from hydrogen, trifluoromethyl and chloro; R15 is selected from hydrogen, chloro and trifluoromethyl; R16 is selected
    Type: Application
    Filed: April 3, 2007
    Publication date: January 21, 2010
    Inventors: Steven Coulton, Martin Gilpin, Roderick Alan Porter
  • Publication number: 20090326027
    Abstract: Compounds of formula (I) and salts and solvates are provided. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: March 14, 2007
    Publication date: December 31, 2009
    Inventors: Steven Coulton, Howard Robert Marshall, David John Nash, Roderick Alan Porter
  • Publication number: 20090325993
    Abstract: Compounds of formula (I) or a salt thereof are provided: wherein R1, R2, R3, R4, R5, R6, R7, R9, R10, X, n, p and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further discloses pharmaceutical compositions and combinations comprising the compounds.
    Type: Application
    Filed: January 30, 2008
    Publication date: December 31, 2009
    Inventors: Nadia Mamoona Ahmad, Justine Yeun Quai Lai, Howard Robert Marshall, David John Nash, Roderick Alan Porter
  • Publication number: 20090318447
    Abstract: The invention provides a compound of formula (I) or a salt or solvate thereof: wherein R1, R2, R3, R4, R5, R6, R7, n, Het and Ar are as defined in the specification, and uses of such compounds. The compounds inhibit GlyT1 transporters and are useful in the treatment of certain neurological and neuropsychiatric disorders, including schizophrenia.
    Type: Application
    Filed: April 15, 2005
    Publication date: December 24, 2009
    Inventors: David John Nash, Roderick Alan Porter
  • Publication number: 20090286828
    Abstract: The present invention relates to compounds of formula (I), or to salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 21, 2005
    Publication date: November 19, 2009
    Inventors: Andrea Bozzoli, Clive Leslie Branch, Jacqueline Anne Macritchie, Howard Robert Marshall, Roderick Alan Porter, Simone Spada
  • Publication number: 20090270510
    Abstract: The present invention relates to compounds of formula (I), or salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 21, 2005
    Publication date: October 29, 2009
    Applicant: GLAXO GROUP LIMITED
    Inventors: Daniel Marcus Bradley, Clive Leslie Branch, Wai Ngor Chan, Steven Coulton, Martin Leonard Gilpin, Andrew Jonathan Harris, Justine Yeun Quai Lai, Jacqueline Anne Macritchie, Howard Robert Marshall, David John Nash, Roderick Alan Porter, Simone Spada, Kevin Michael Thewlis, Simon Edward Ward
  • Publication number: 20090227629
    Abstract: The present invention relates to compounds of formula (I), salts or solvates thereof, their use in the manufacture of medicaments for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof. wherein R1, R2, R3, R4, R5, R6 and n are as defined in the description.
    Type: Application
    Filed: January 8, 2007
    Publication date: September 10, 2009
    Inventors: Clive Leslie Branch, Jacqueline Anne Macritchie, Howard Marshall, Roderick Alan Porter, Simone Spada
  • Publication number: 20090175788
    Abstract: Compounds of formula (I) and salts and solvates thereof, which are radiolabelled ligands for the glycine 1 transporter, are provided: wherein R1 is 3H, or a C1-6alkyl group incorporating a radionuclide selected from the group consisting of 3H, 11C, 14C, 13N, 15O, 76Br, 18F, 123I, 125I, 131I, 75Br, 76Br, 77Br and 82Br. Use of the compounds for the labelling and diagnostic imaging of the glycine 1 transporter functionality is disclosed.
    Type: Application
    Filed: June 20, 2007
    Publication date: July 9, 2009
    Inventors: Gabriella Gentile, Hugh Jonathan Herdon, Johannes Passchier, Roderick Alan Porter
  • Publication number: 20090093478
    Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: wherein the substituent variables are as defined herein, and their use as pharmaceuticals.
    Type: Application
    Filed: October 26, 2007
    Publication date: April 9, 2009
    Inventors: Clive Leslie BRANCH, Steven Coulton, Amanda Johns, Christopher Norbert Johnson, Roderick Alan Porter, Geoffrey Stemp, Kevin Thewlis
  • Publication number: 20090082390
    Abstract: This invention relates to N-aroyl cyclic amine derivatives and their use as pharmaceuticals, specifically as orexin receptor antagonists.
    Type: Application
    Filed: July 8, 2008
    Publication date: March 26, 2009
    Inventors: Wai Ngor CHAN, Amanda Johns, Christopher Norbert Johnson, Riccardo Novelli, Roderick Alan Porter
  • Publication number: 20090062360
    Abstract: Compounds of formula (I) and salts and solvates thereof are provided: wherein R1 to R8 and n are defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
    Type: Application
    Filed: March 14, 2007
    Publication date: March 5, 2009
    Inventors: Steven Coulton, Howard Robert Marshall, David John Nash, Roderick Alan Porter
  • Publication number: 20090036442
    Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.
    Type: Application
    Filed: October 29, 2007
    Publication date: February 5, 2009
    Inventors: Clive Leslie BRANCH, Wai Ngor Chan, Amanda Johns, Christopher Norbert Johnson, David John Nash, Riccardo Novelli, Jean-Pierre Pilleux, Roderick Alan Porter, Rachel Elizabeth Anne Stead, Geoffrey Stemp
  • Publication number: 20090029986
    Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: wherein the substituent variables are as defined herein, and their use as pharmaceuticals.
    Type: Application
    Filed: October 29, 2007
    Publication date: January 29, 2009
    Inventors: Clive Leslie BRANCH, Steven Coulton, Amanda Johns, Christopher Norbert Johnson, Roderick Alan Porter, Geoffrey Stemp, Kevin Thewlis