Abstract: A method of reducing levels of E. coli O157 strains within the gastrointestinal tract of a ruminant animal using specific bacteriophage(s) is herein described. Also described is a pharmaceutical composition comprising at least one of said bacteriophages and a method for isolating or selecting bacteriophages useful in reducing E. coli O157 levels as described above.

Abstract: The present invention relates to liquid projection apparatus in the form of a face-shooter array. Material layers are used as the basis to fabricate the device to overcome constructional difficulties associated with other technologies. The device utilizes excitation of the surface layers (100) incorporating nozzles (8) which are arranged over one surface layer with addressability, forming a liquid projection array, capable of operation at high frequencies with a wide range of liquids.

Abstract: A hybrid tool serves as a form on which constituent materials are applied for bonding or curing into a part in a desired configuration. It also serves as a holder for the bonded or cured materials in the originally applied position during subsequent machining. The hybrid tool is made by fabricating a face sheet of composite material having a facing surface configured to the reverse of a desired shape of one surface of a part to be made on the tool. The actual part will be laid up on the facing surface, cured while on the tool, and even trimmed before release. Base structure of the tool holds the facing surface of the face sheet in the desired shape, and includes ground-engaging pads that define an “A” datum plane. The tool aligns a reference plane of the face sheet parallel to the datum plane. A substantially continuous groove in the face sheet, used for trimming the part, opens in the facing surface.

Abstract: The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyclases known. The present invention also discloses a method for measuring the inhibition of adenylyl cyclase activity.

Abstract: The floating rope marker is comprised of a rope assembly having a braided hollow rope with an upper end portion being turned in and threaded back inside itself and a lower end portion being turned in through a side wall of the rope and threaded back inside the rope to form a loop so that the two end portions of the rope are close together within the rope. A cylindrical float member is inserted in the turned in portion of the upper end and a section of heat shrinkable tubing is shrunk on the lower end portion of the rope to hold the turned in portion of the lower end porton in place. A hook having a base is held in the lower end portion loop and a hook part adapted for releasably holding a fish extends downwardly in the water.

Abstract: A hybrid tool serves as a form on which constituent materials are applied for bonding or curing into a part in a desired configuration. It also serves as a holder for the bonded or cured materials in the originally applied position during subsequent machining. The hybrid tool is made by fabricating a face sheet of composite material having a facing surface configured to the reverse of a desired shape of one surface of a part to be made on the tool. The actual part will be laid up on the facing surface, cured while on the tool, and even trimmed before release. Base structure of the tool holds the facing surface of the face sheet in the desired shape, and includes ground-engaging pads that define an "A" datum plane. The tool aligns a reference plane of the face sheet parallel to the datum plane. A substantially continuous groove in the face sheet, used for trimming the part, opens in the facing surface.

Abstract: The repair method includes removing eroded or damaged trailing edge portions of partitions in the diaphragm of a turbine, over 50% of the length of the partitions being removed commencing at the trailing edge. A coupon which is a precise replication of a portion of an originally specified partition is welded to the remaining or extant partition portion by a seal weld along the radial length of the coupon on the suction side of the repaired partition and two full penetration welds at the ends of the coupon to secure it to the inner and outer rings or side walls of the diaphragm. The repaired partition is thus substantially identically contoured as the original partition.

Abstract: A hard facing alloy is applied to a surface of a substrate by making a mixture of at least two constituents whose net composition is the desired hard facing alloy composition. The constituents have different solidus temperatures, at least one of which is above a processing temperature of the substrate and another of which is below the processing temperature of the substrate. In one preferred approach, the mixture is prepared by pressing and lightly sintering the constituents in the form of powders, so that the mixture retains its shape and can be attached to the substrate surface. Then the substrate is heated to the processing temperature and maintained for a time sufficient to permit interdiffusion of the several different phases toward a homogeneous hard facing alloy composition uniformly through a major portion of the volume.

Abstract: The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyclases known. The present invention also discloses a method for measuring the inhibition of adenylyl cyclase activity.

Abstract: The repair method includes removing eroded or damaged trailing edge portions of partitions in the diaphragm of a turbine, over 50% of the length of the partitions being removed commencing at the trailing edge. A coupon which is a precise replication of a portion of an originally specified partition is welded to the remaining or extant partition portion by a seal weld along the radial length of the coupon on the suction side of the repaired partition and two full penetration welds at the ends of the coupon to secure it to the inner and outer rings or side walls of the diaphragm. The repaired partition is thus substantially identically contoured as the original partition.

Abstract: At predetermined low speeds, a safety brake is applied directly to the hoisting drum at a setting sufficiently high to stop the load from falling should drive line failure occur. The load can be lowered or raised by applying sufficient torque to the drum to overcome the braking force and thus lower or raise the load. If drive train failure occurs, the brake will instantaneously stop the load without further uncontrolled movement.

Abstract: A shut-off valve for a spin-on filter includes a generally cylindrical outer housing which has an open top surface and an annular spring channel formed in that top surface for receipt of a coil spring. The spring is positioned so as to act on a valve actuator and gasket combination which are moveable relative to a valve seat for opening and closing the shut-off valve. In the normally closed condition the spring exerts a spring biasing force on the upper portion of the valve actuator which pushes it against the gasket and pushes the gasket against the outer sealing ridge of the valve seat. In this condition any liquid flowing into the top center opening of the housing will not be allowed to pass through the lowered centered opening of the valve seat. However, when the spin-on filter which includes the shut-off valve is spun onto a mounting base a stem on that mounting base pushes upwardly on the valve actuator compressing the spring and creating a liquid flow path between the gasket and the valve seat.

Abstract: A double-enveloped lamp assembly includes a light-source capsule subject to burst on rare occasions, a light-transmissive shield substantially surrounding the light-source capsule for absorbing and dissipating a portion of the energy when the light-source capsule bursts, a mesh of substantially nonconducting fiber for reinforcing the shield, and a light-transmissive outer envelope. The mesh is fabricated of ceramic fibers having sufficient strength to reinforce the shield. Since the fibers are nonconducting, sodium migration is minimized. The ceramic fiber mesh is particularly useful for high wattage lamps where thick-walled outer envelopes are not practical.

Abstract: A ceramic arc tube assembly for an arc discharge lamp includes an arc tube having openings for electrode feedthroughs at opposite ends. The feedthroughs each comprise a niobium tube having a tungsten electrode welded to it. A connection wire is welded to the feedthrough at or near the end of the niobium tube, and the feedthrough is subsequently sealed into the arc tube with the connection wire abutting the arc tube. Since the connection wire is prewelded to the feedthrough, the feedthrough can be made as short as practicable without risk of damaging the seal during welding. As a result, feedthrough material cost is substantially reduced. Preferably, the connection wire is used for locating the feedthrough in the arc tube during seal formation.

Abstract: An improved prosthesis construction in a femoral-side hip joint replacement device of the type having an elongate curved stem held within an intramedullary cavity in a femur, and a neck supporting a ball-like joint member at the femur's proximal end. The construction includes an elongate polymer core containing continuous-filament fibers oriented substantially along the length of the core. The core contains the neck, an elongate distal stem whose cross-sectional area is less than about one-quarter that of the neck, and a tapered sections which mates the neck to the stem. A polymer skin fused to and covering the stem and tapered section of the core is shaped and dimensioned to conform to and fill the bone cavity. A braided sheath encases the stem and tapered sections of the core and it embedded in the polymer skin adjacent the core.

Abstract: A patient transport device which is characterized in one embodiment by a flat rail bed having spaced, parallel, upturned rails on opposite sides, with a seat slidably disposed over the rails by means of rollers rotating in the rails on spaced axles carried by the seat. The device is designed to transport patients from one side of a bed to the other, as well as to and from wheelchairs and dollys. In another embodiment, the seat is enlarged to define a body support, the body support and rail bed combination is supported by hydraulic cylinders to facilitate height adjustment and the larger patient transport device is used to transport patients to and from x-ray tables, dollys, hospital beds and the like.

Abstract: The safety system in a hoist having a motor with a motor shaft, a gear reduction unit, a drum, a safety brake drivingly coupled on an operating element on or close to the drum in which a mechanical out-of-sync detector produces a unidirectional brake-setting output from inputs from the drum and the motor shaft, the unidirectional brake-setting rotational output for setting the brake. In a preferred embodiment, an error correction is made into the detector for obtaining a first unidirectional output during normal operation, and the brake-setting unidirectional rotation is in the opposite direction for setting the brake. One form of detector is a mechanical differential assembly and another form of detector is a set of coaxial shafts that measure differential rotation between the drum and motor input shafts. A unique brake actuator is provided and is easily reset remotely after the brake has been set.

Abstract: ATP and other nucleoside triphosphates labeled in the .gamma.-phosphate with .sup.32 P are prepared from L-.alpha.-glycerophosphate and their corresponding nucleoside diphosphates by a series of enzymatic reactions in the presence of NAD.sup.+, preferably regenerated by lactate dehydrogenase and pyruvate. The resulting [.gamma.-.sup.32 P]nucleotides are useful as reagents for analytical determinations.

Abstract: In a process for preparing pigmentary .gamma.-quinacridone by oxidizing .beta.-dihydroquinacridone with a mild alkali-stable oxidizing agent in a liquid medium consisting of alkali metal hydroxide, water and a polar, alkali-stable, water-soluble organic liquid, this invention provides for an improvement wherein the oxidation is conducted in the presence of 0.1% to 1% by weight of an o-carboxybenzamidomethyl quinacridone compound whereby the resulting .gamma.-quinacridone exhibits sufficiently high strength so that milling or solvent treatments to increase pigment strength are unnecessary.