Patents by Inventor Roger Crystal

Roger Crystal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-view learning in detection of psychological states
    Patent number: 9792823
    Abstract: Systems and methods for using multi-view learning to leverage highly informative, high-cost, psychophysiological data collected in a laboratory setting, to improve post-traumatic stress disorder (PTSD) screening in the field, where only less-informative, low-cost, speech data are available. Partial least squares (PLS) methods can be used to learn a bilinear factor model, which projects speech and EEG responses onto latent spaces, where the covariance between the projections is maximized. The systems and methods use a speech representation based on a combination of audio and language descriptors extracted from spoken responses to open-ended questions.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: October 17, 2017
    Assignee: Raytheon BBN Technologies Corp.
    Inventors: Xiaodan Zhuang, Viktor Rozgic, Michael Roger Crystal
  • Nasal drug products and methods of their use
    Patent number: 9775838
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: October 3, 2017
    Assignees: ADAPT PHARMA LIMITED, OPIANT PHARMACEUTICALS
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20170239241
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: May 8, 2017
    Publication date: August 24, 2017
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • Nasal drug products and methods of their use
    Patent number: 9707226
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: July 18, 2017
    Assignees: ADAPT PHARMA LIMITED, OPIANT PHARMACEUTICALS
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20170151231
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: February 9, 2017
    Publication date: June 1, 2017
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20170151230
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: January 25, 2017
    Publication date: June 1, 2017
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • Nasal drug products and methods of their use
    Patent number: 9629965
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: April 25, 2017
    Assignee: Opiant Pharmaceuticals, Inc.
    Inventors: Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20170071851
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: September 16, 2016
    Publication date: March 16, 2017
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20170043107
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: October 26, 2016
    Publication date: February 16, 2017
    Inventors: Roger CRYSTAL, Michael Brenner WEISS
  • Nasal drug products and methods of their use
    Patent number: 9561177
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: February 7, 2017
    Assignees: ADAPT PHARMA LIMITED, OPIANT PHARMACEUTICALS
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • Nasal drug products and methods of their use
    Patent number: 9480644
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: November 1, 2016
    Assignee: Opiant Pharmaceuticals, Inc.
    Inventors: Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20160303041
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 20, 2016
    Inventors: Fintan Keegan, Robert Gerard Bell, Roger Crystal, Michael Brenner Weiss
  • Nasal drug products and methods of their use
    Patent number: 9468747
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: October 18, 2016
    Assignee: Opiant Pharmaceuticals, Inc.
    Inventors: Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20160184294
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: November 24, 2015
    Publication date: June 30, 2016
    Inventors: Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20160166503
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: November 16, 2015
    Publication date: June 16, 2016
    Inventors: Roger Crystal, Michael Brenner Weiss
  • MULTI-VIEW LEARNING IN DETECTION OF PSYCHOLOGICAL STATES
    Publication number: 20160078771
    Abstract: Systems and methods for using multi-view learning to leverage highly informative, high-cost, psychophysiological data collected in a laboratory setting, to improve post-traumatic stress disorder (PTSD) screening in the field, where only less-informative, low-cost, speech data are available. Partial least squares (PLS) methods can be used to learn a bilinear factor model, which projects speech and EEG responses onto latent spaces, where the covariance between the projections is maximized. The systems and methods use a speech representation based on a combination of audio and language descriptors extracted from spoken responses to open-ended questions.
    Type: Application
    Filed: September 15, 2014
    Publication date: March 17, 2016
    Inventors: Xiaodan Zhuang, Viktor Rozgic, Michael Roger Crystal
  • CO-PACKAGED DRUG PRODUCTS
    Publication number: 20160008277
    Abstract: Provided herein are drug products comprising a combination of an opioid receptor agonist and an opioid receptor agonists, including co-packaged drug products comprising an opioid receptor agonist and an opioid receptor antagonist in a delivery device selected from a hand-held auto-injector and a pre-primed nasal delivery device, and methods of prescribing and dispensing same. Methods of lowering opioid overdose risk by providing a combination of an opioid receptor agonist and an opioid receptor agonists, for example by co-packaging an opioid receptor agonist and an opioid receptor antagonist in a delivery device, are also provided.
    Type: Application
    Filed: July 9, 2015
    Publication date: January 14, 2016
    Inventors: Roger Crystal, Michael Brenner Weiss
  • Nasal drug products and methods of their use
    Patent number: 9211253
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: December 15, 2015
    Assignee: Lightlake Therapeutics Inc.
    Inventors: Roger Crystal, Michael Brenner Weiss
  • NASAL DRUG PRODUCTS AND METHODS OF THEIR USE
    Publication number: 20150258019
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.
    Type: Application
    Filed: March 16, 2015
    Publication date: September 17, 2015
    Inventors: Roger Crystal, Michael Brenner Weiss