Patents by Inventor Roger Evans

Roger Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL TRIAZOLO[4,5-D]PYRIMIDINES
    Publication number: 20170204103
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 and n are defined as in the description and in the claims. The compound of formula (I) can be for treating.
    Type: Application
    Filed: April 4, 2017
    Publication date: July 20, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Uwe Grether, Matthias Nettekoven, Mark Rogers-Evans, Sebastien Schmitt, Benjamin James Stenton
  • Pyrazol derivatives
    Patent number: 9694012
    Abstract: The invention relates to a compound of formula (I) wherein A1 to A3 and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: July 4, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Fabienne Ricklin, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch
  • RADIOLABELED CANNABINOID RECEPTOR 2 LIGAND
    Publication number: 20170166534
    Abstract: The present invention relates to a compound of formula (I) wherein R1 is defined as in the description and in the claims. The compound of formula (I) can be used as radiolabeled ligand.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Applicants: Hoffmann-La Roche Inc., EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH, UNIVERSITÄT ZÜRICH
    Inventors: Simon M. Ametamey, Juergen Fingerle, Luca Gobbi, Uwe Grether, Ahmed Haider, Thomas Hartung, Linjing Mu, Leo Nicholls, Mark Rogers-Evans, Christoph Ullmer
  • 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS
    Publication number: 20170157137
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R1, R3, R4, L1, L2, L3, L4, and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Applicant: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Mark Rogers-Evans
  • Substituted Pyridine Compounds Having Herbicidal Activity
    Publication number: 20170121343
    Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.
    Type: Application
    Filed: April 7, 2015
    Publication date: May 4, 2017
    Inventors: Gilbert BESONG, Matthias WITSCHEL, Ruediger REINGRUBER, Helmut KRAUS, Thomas SEITZ, Liliana PARRA RAPADO, Trevor William NEWTON, Gerd KRAEMER, Richard Roger EVANS, Michael RACK
  • Herbicidal Compositions Comprising Isoxazolo[5,4-B]Pyridines
    Publication number: 20170112130
    Abstract: The present invention relates to herbicidal compositions comprising an isoxazolo[5,4-b]pyridine and at least one further compound selected from herbicidally active compounds and, if desired, safeners. The present invention also relates to the use of such a composition for controlling unwanted vegetation and to a method for controlling unwanted vegetation, which comprises allowing a composition to act on plants, their seeds and/or their habitat.
    Type: Application
    Filed: April 8, 2015
    Publication date: April 27, 2017
    Inventors: Johannes HUTZLER, Helmut KRAUS, Anna Aleksandra MICHROWSKA-PIANOWSKA, Yogesh OTURKAR, Trevor William NEWTON, Stefan TRESCH, Jens LERCHL, Thomas SEITZ, Richard Roger EVANS, Klaus KREUZ, Ulrich STEINBRENNER
  • 2,7-diazaspiro[3.5]nonane compounds
    Patent number: 9617264
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R1, R3, R4, L1, L2, L3, L4, and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: April 11, 2017
    Assignee: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Mark Rogers-Evans
  • Herbicidal isoxazolo[5,4-b]pyridines
    Patent number: 9609870
    Abstract: The invention relates to isoxazolo[5,4-b]pyridine compounds of formula I, to the agriculturally useful salts of isoxazolo[5,4-b]pyridine compounds of formula I, and to their use as herbicides.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: April 4, 2017
    Assignee: BASF SE
    Inventors: Anna Aleksandra Michrowska-Pianowska, Julia Major, Johannes Hutzler, Trevor William Newton, Richard Roger Evans, Klaus Kreuz, Klaus Grossmann, Dschun Song, Anja Simon, Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Tao Qu, Frank Stelzer, Helmut Kraus, Thomas Seitz, Andree van der Kloet, Ruediger Reingruber
  • OXADIAZOLE COMPOUNDS
    Publication number: 20170073319
    Abstract: The present invention relates to a compound of formula (I) or (II) or a stereoisomer, enantiomer, racemic, or tautomer thereof, (I) (II) wherein R1, R2, R3, L1, L2, L3, L4, L5 and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Application
    Filed: March 17, 2015
    Publication date: March 16, 2017
    Applicant: REMYND NV
    Inventors: Gerard GRIFFIOEN, Bart DE TAEYE, Katrien PRINCEN, Koen DE WITTE, Emilie BLANCHE, Hasane RATNI, Matthias NETTEKOVEN, Mark ROGERS-EVANS
  • Triazolo[4,5-D]pyrimidine derivatives
    Patent number: 9593123
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: March 14, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Grether, Matthias Nettekoven, Mark Rogers-Evans, Stephan Roever, Sebastien Schmitt, Atsushi Kimbara
  • Pyrrolo[2,3-D]pyrimidine derivatives as CB2 receptor agonists
    Patent number: 9580435
    Abstract: The invention relates to a compound of formula (I) wherein A and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: February 28, 2017
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch
  • NOVEL PYRAZOL DERIVATIVES
    Publication number: 20170035769
    Abstract: The invention relates to a compound of formula (I) wherein A1 to A3 and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: October 24, 2016
    Publication date: February 9, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: UWE GRETHER, ATSUSHI KIMBARA, MATTHIAS NETTEKOVEN, FABIENNE RICKLIN, STEPHAN ROEVER, MARK ROGERS-EVANS, TANJA SCHULZ-GASCH
  • Herbicidal azines
    Patent number: 9549558
    Abstract: The present invention relates to azines of formula (I) wherein the variables are defined according to the description, processes and intermediated for preparing them, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants and a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one azine of the formula I to act on plants, their seed and/or their habitat.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: January 24, 2017
    Assignee: BASF SE
    Inventors: Trevor William Newton, Florian Vogt, Julia Major, Kristin Hanzlik, Liliana Parra Rapado, Markus Kordes, Thomas Seitz, Matthias Witschel, Klaus Kreuz, Johannes Hutzler, Richard Roger Evans, Jens Lerchl
  • 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS
    Publication number: 20170015665
    Abstract: The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R1, R3, R4, L1, L2, L3, L4, and n, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of metabolic disorders and/or neurodegenerative diseases, and/or protein misfolding disorders.
    Type: Application
    Filed: March 17, 2015
    Publication date: January 19, 2017
    Applicant: REMYND NV
    Inventors: Gerard Griffioen, Bart De Taeye, Katrien Princen, Koen De Witte, Emilie Blanche, Hasane Ratni, Mark Rogers-Evans
  • BACE1 inhibitors
    Patent number: 9540397
    Abstract: The present invention provides a compound of formula I, having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: January 10, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bjoern Bartels, Philipp Cueni, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Walter Vifian, Thomas Woltering
  • NOVEL PYRIDINE DERIVATIVES
    Publication number: 20160376262
    Abstract: The invention relates to a compound of formula (I) wherein A and R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 9, 2016
    Publication date: December 29, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Luca Gobbi, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans
  • NOVEL PYRIDINE DERIVATIVES
    Publication number: 20160376237
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Application
    Filed: September 9, 2016
    Publication date: December 29, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Luca Gobbi, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Roger Slavik
  • Pyridine derivatives
    Patent number: 9522886
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: December 20, 2016
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Beat Frei, Luca Gobbi, Uwe Grether, Atsushi Kimbara, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch
  • Pyrazine derivatives as CB2 receptor agonists
    Patent number: 9512141
    Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 receptor agonist for use in the treatment of several disorders, such as pain, atherosclerosis and glaucoma.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: December 6, 2016
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Baledi Dhurwasulu, Uwe Grether, Matthias Nettekoven, Stephan Roever, Mark Rogers-Evans, Tanja Schulz-Gasch
  • Pyrazole compounds as CB2 agonists
    Patent number: 9512132
    Abstract: The invention relates to a compound of formula (I) wherein A1 to A3 and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: December 6, 2016
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Uwe Grether, Atsushi Kimbara, Nettekoven Matthias, Ricklin Fabienne, Roever Stephan, Mark Rogers-Evans, Tanja Schulz-Gasch