Patents by Inventor Roland Callens

Roland Callens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200095303
    Abstract: The present invention relates to compounds comprising a quaternary ammonium group, their use in skin diseases, and their preparation.
    Type: Application
    Filed: November 27, 2019
    Publication date: March 26, 2020
    Inventors: Philippe WOLGEN, Roland CALLENS
  • Patent number: 10508142
    Abstract: The present invention relates to compounds comprising a quaternary ammonium group, their use in skin diseases, and their preparation.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: December 17, 2019
    Assignee: VALLAURIX PTE. LTD.
    Inventors: Philippe Wolgen, Roland Callens
  • Patent number: 10174075
    Abstract: Process for the separation of a biomolecule containing at least one cationic group from a liquid medium containing the biomolecule, which includes the use of a tetraphenylborate (TPB) salt.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: January 8, 2019
    Assignee: CORDEN PHARMA BRUSSELS PC
    Inventors: Roland Callens, Laurent Jeannin
  • Publication number: 20180094039
    Abstract: The present invention relates to compounds comprising a quaternary ammonium group, their use in skin diseases, and their preparation.
    Type: Application
    Filed: April 28, 2016
    Publication date: April 5, 2018
    Inventors: Philippe WOLGEN, Roland CALLENS
  • Publication number: 20180086789
    Abstract: The present invention relates to an alpha-MSH analogue compound, the use in skin diseases, and the preparation.
    Type: Application
    Filed: April 28, 2016
    Publication date: March 29, 2018
    Inventors: Philippe WOLGEN, Roland CALLENS
  • Publication number: 20170183375
    Abstract: Process for the separation of a biomolecule containing at least one cationic group from a liquid medium containing said biomolecule, which comprises the use of a tetraphenylborate (TPB) salt.
    Type: Application
    Filed: March 6, 2017
    Publication date: June 29, 2017
    Inventors: Roland Callens, Laurent Jeannin
  • Patent number: 9611291
    Abstract: Process for the separation of a biomolecule containing at least one cationic group from a liquid medium containing said biomolecule, which comprises the use of a tetraphenylborate (TPB) salt.
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: April 4, 2017
    Assignee: CORDEN PHARMA BRUSSELS PC
    Inventors: Roland Callens, Laurent Jeannin
  • Patent number: 9409946
    Abstract: A process for the manufacture of peptide Omiganan in solution phase. Novel intermediates in the process for the manufacture of Omiganan and processes for the manufacture of these intermediates.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: August 9, 2016
    Assignee: PEPTISYNTHA
    Inventors: Roland Callens, Laurent Jeannin, Georges Blondeel
  • Patent number: 9175019
    Abstract: The present invention relates to a process for producing N-alkyl-N-trialkylsilylamides from trialkylsilylhalides and N-alkylamides in the presence of a base and in the absence of a solvent.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: November 3, 2015
    Assignee: PEPTISYNTHA SA
    Inventors: Roland Callens, Andre Collin
  • Patent number: 9051349
    Abstract: The invention provides crystalline forms of the peptide Gly-Gly-Val-Leu-Val-Gln-Pro-Gly (SEQ ID NO 1), and salts of the peptide, which may further have associated water molecules. These salts and hydrated salts of the peptide and compositions comprising these materials have advantageous pharmaceutical properties.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 9, 2015
    Assignee: Alba Therapeutics Corporation
    Inventors: Roland Callens, Georges Blondeel, Thierry Delplanche
  • Publication number: 20140024805
    Abstract: The present invention relates to a process for producing N-alkyl-N-trialkylsilylamides from trialkylsilylhalides and N-alkylamides in the presence of a base and in the absence of a solvent.
    Type: Application
    Filed: April 2, 2012
    Publication date: January 23, 2014
    Applicant: SOLVAY S.A.
    Inventors: Roland Callens, Andre Collin
  • Publication number: 20130281602
    Abstract: A thermo-responsive polymer covalently bound with a peptide, wherein the peptide comprises a peptide moiety that is able to self-assemble and a functional peptide moiety comprising a bioactive sequence, and compositions comprising such thermo-responsive polymer covalently bound with a peptide. Methods for the preparation of such thermo-responsive polymers covalently bound with a peptide and the use thereof for the preparation of hydrogels.
    Type: Application
    Filed: October 6, 2011
    Publication date: October 24, 2013
    Applicant: SOLVAY SA
    Inventors: Alberto Saiani, Aline Miller, Roland Callens, Laurent Jeannin, Wafa Moussa
  • Patent number: 8546530
    Abstract: Process for the manufacture of a peptide or peptide analog, which comprises (a) producing a persilylated peptide or persilylated peptide analogue by silylating a corresponding peptide by reaction with a silylating agent other than trimethylsilylcyanide, and (b) reacting a compound of formula (I) X-A-COOH wherein X is an amino protecting group, A is an amino acid, peptide or peptide analogue residue, and —COOH designates an optionally activated carboxylic group, with a persilylated peptide or a persilylated peptide analogue containing from 4 to 15 amino acids.
    Type: Grant
    Filed: November 18, 2008
    Date of Patent: October 1, 2013
    Assignee: Solvay (Societe Anonyme)
    Inventors: Roland Callens, Thierry Delplanche
  • Publication number: 20130210147
    Abstract: Use of the amino acid sequence Har-Gly-Asp (hRGD) as a bioactive sequence in functional peptides to promote cell adhesion, cell growth, and/or cell differentiation, and in the preparation of hydrogels, preferably hydrogels for cell culture. A hydrogel comprising the hRGD sequence, especially a hydrogel wherein the hRGD sequence is part of the hydrogel scaffold.
    Type: Application
    Filed: October 6, 2011
    Publication date: August 15, 2013
    Applicant: SOLVAY SA
    Inventors: Laurent Jeannin, Roland Callens, Wafa Moussa
  • Patent number: 8415454
    Abstract: A process for manufacturing a cyclic peptide which comprises providing a cyclic peptide bonded to a Merrifield-type resin and cleaving the cyclic peptide from the Merrifield type resin by transesterification.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: April 9, 2013
    Assignee: Solvay (Société Anonyme)
    Inventors: Satish Joshi, Shima Joshi, Bernhard Freimann, Manuel Ramos, Roland Callens
  • Publication number: 20110105722
    Abstract: Method for preparing a peptide or a peptide derivative which comprises it least one step in which a free amino acid or a free peptide is reacted with a urethane-protected amino acid N-carboxyanhydride (UNCA) solution.
    Type: Application
    Filed: March 6, 2009
    Publication date: May 5, 2011
    Applicant: SOLVAY (SOCIETE ANONYME)
    Inventors: Roland Callens, Laurent Jeannin
  • Publication number: 20110098446
    Abstract: Process for the separation of a biomolecule containing at least one cationic group from a liquid medium containing said biomolecule, which comprises the use of a tetraphenylborate (TPB) salt.
    Type: Application
    Filed: June 17, 2009
    Publication date: April 28, 2011
    Applicant: SOLVAY (SOCIETE ANONYME)
    Inventors: Roland Callens, Laurent Jeannin
  • Publication number: 20110092671
    Abstract: A process for the manufacture of peptide Omiganan in solution phase. Novel intermediates in the process for the manufacture of Omiganan and processes for the manufacture of these intermediates.
    Type: Application
    Filed: June 17, 2008
    Publication date: April 21, 2011
    Applicant: SOLVAY (SOCIETE ANONYME)
    Inventors: Roland Callens, Laurent Jeannin, Georges Blondeel
  • Publication number: 20100298537
    Abstract: Process for the manufacture of a peptide or peptide analog, which comprises (a) producing a persilylated peptide or persilylated peptide analogue by silylating a corresponding peptide by reaction with a silylating agent other than trimethylsilylcyanide, and (b) reacting a compound of formula (I) X-A-COOH wherein X is an amino protecting group, A is an amino acid, peptide or peptide analogue residue, and —COOH designates an optionally activated carboxylic group, with a persilylated peptide or a persilylated peptide analogue containing from 4 to 15 amino acids.
    Type: Application
    Filed: November 18, 2008
    Publication date: November 25, 2010
    Applicant: SOLVAY (SOCIETE ANONYME)
    Inventors: Roland Callens, Thierry Delplanche
  • Publication number: 20100280221
    Abstract: Processes for the synthesis and purification of a Gly-Gly-Val-Leu-Val-Gln-Pro-Gly octapeptide (SEQ ID NO 1).
    Type: Application
    Filed: November 21, 2008
    Publication date: November 4, 2010
    Applicant: SOLVAY (SOCIETE ANONYME)
    Inventors: Roland Callens, Georges Blondeel, Thierry Delplanche