Abstract: There is provided a method and apparatus for adjusting a model of an anatomical structure in a sequence of images of the anatomical structure. The model is placed with respect to the anatomical structure in the sequence of images. A user input is received to adjust the model in a selected image of the sequence, and based on the user input, a part of the model that lies in the selected image and a previously unadjusted part of the model that lies in one or more other images of the sequence is adjusted, whilst fixing in place a previously adjusted part of the model that lies in other images of the sequence.

Abstract: There is provided a method and apparatus for adjusting a model of an anatomical structure in a sequence of images of the anatomical structure. The model is placed with respect to the anatomical structure in the sequence of images. A user input is received to adjust the model in a selected image of the sequence, and based on the user input, a part of the model that lies in the selected image and a previously unadjusted part of the model that lies in one or more other images of the sequence is adjusted, whilst fixing in place a previously adjusted part of the model that lies in other images of the sequence.

Abstract: Systems and methods are provided for generating and using statistical data which is indicative of a difference in shape of a type of anatomical structure between images acquired by a first imaging modality and images acquired by a second imaging modality. This statistical data may then be used to modify a first segmentation of the anatomical structure which is obtained from an image acquired by the first imaging modality so as to predict the shape of the anatomical structure in the second imaging modality, or in general, to generate a second segmentation of the anatomical structure as it may appear in the second imaging modality based on the statistical data and the first segmentation.

Abstract: The invention relates to a dynamic sliding-window-like initialization for, for example, iterative VMAT algorithms. Specifically, a dynamic sliding window conversion method is contemplated where typical dynamic VMAT constraints are taken into account to find an optimal set of suitable openings (i.e. binary masks) that can be used as quasi-feasible start initialization for any VMAT algorithm that can refine until a deliverable plan is reached. Here, a multileaf leaf tip trajectory least square constrained optimization is performed to find a set of optimal unidirectional trajectories for all MLC leaf pairs of all arc points. To ensure that a quasi-feasible (or better quasi-deliverable) solution is returned, for example, a maximum dose rate, a maximum gantry speed, a maximum leafs speed, and a maximum treatment time may be enforced.

Abstract: There is provided a method and apparatus for segmenting two-dimensional images of an anatomical structure. A time sequence of two-dimensional images of the anatomical structure is acquired (202) and a segmentation model for the anatomical structure is acquired (204). The segmentation model comprises a plurality of segments. The acquired segmentation model is applied to the entire time sequence of two-dimensional images of the anatomical structure simultaneously in time and space to segment the time sequence of two-dimensional images by way of the plurality of segments (206).

Abstract: The present invention relates to a system, a corresponding method and computer program for assessing outflow tract obstruction of a heart of a subject, the system comprising a unit (10) for providing a geometrical model of the heart, a unit (20) for providing a volumetric image of the heart, a unit (30) for adapting the geometrical model to the volumetric image to obtain an adapted model (32), a unit (40) for providing an implant model (44) of an implant and for constructing the implant model (44) into the adapted model (32) to obtain an enhanced model (42), a unit (60) for determining a trajectory curve (62) through an outflow tract (52), and a unit (50) for assessing outflow tract obstruction based on the adapted model (32), the enhanced model (42) and the trajectory curve (62). The invention allows for an improved assessing of an outflow tract obstruction of a heart of a subject.

Abstract: There is provided a method and apparatus for segmenting a two-dimensional image of an anatomical structure. A three-dimensional model of the anatomical structure is acquired (202). The three-dimensional model comprises a plurality of segments. The acquired three-dimensional model is adapted to align the acquired three-dimensional model with the two-dimensional image (204). The two-dimensional image is segmented by the plurality of segments of the adapted three-dimensional model.

Abstract: The invention relates to a system and a method for evaluating a treatment plan for an external radiation therapy treatment, the treatment plan comprising parameters for controlling an external radiation therapy apparatus during the treatment. The system comprises a database storing historic treatment plans and storing for each historic treatment plan a quality parameter indicative of whether a deviation between a planned dose distribution and a measured dose distribution resulting from an execution of the treatment plan is within an acceptable limit. An evaluation unit determines a threshold value for each of a plurality of treatment plan metrics based on the historic treatment plans and the associated quality parameters. Further, the evaluation unit calculates a value of each of the metrics for the treatment plan and compares the value of each of the metrics with the threshold value determined for the respective metric.

Abstract: A system and method are provided for use in evaluating a clinical guideline which is represented in a machine readable version by a decision tree comprising at least one node and a decision rule associated with the node. The decision rule comprises at least one variable representing a biomedical quantity. The biomedical quantity is extracted from the patient data using an ontology which defines concepts and their relationships in a medical domain of the clinical guideline and which thereby relates the variable of the decision rule to the patient data. If said extraction is not possible, a view of the patient data is presented to the user to enable the user to determine the biomedical quantity from the view. Advantageously, the user is assisted in evaluating the clinical guideline even when it is not possible to automatically extract the biomedical quantity from the patient data.

Abstract: In planning of radiation therapy treatment of at least one structure in a region of a patient body, a first treatment plan is generated on the basis of a planning image of the body region and on the basis of dose objectives. A further image of the body region of the patient body is received, and a transformation is determined for generating an adapted treatment plan from the first treatment plan and/or for generating an adapted dose distribution from the dose distribution corresponding to the first treatment plan on the basis of the further image and determines an adapted treatment plan on the basis of the transformation and/or the adapted dose distribution. The transformation on the basis of the dose objectives. In adapting the dose distribution, an efficient iterative dosimetric patient setup optimization may be employed to reduce the dose computations.