Abstract: A method for applying reactive films containing solids to microporous membranes is provided wherein the membrane is firstly moistened and the reactive film containing solids is applied to the membrane while it is still moist. Membranes produced in this manner can contain reactive films having a high proportion of film openers and can be used advantageously in diagnostic elements for detecting constituents and, in particular, large hydrophobic analytes in body fluids.

Abstract: A method for applying reactive films containing solids to microporous membranes is provided wherein the membrane is firstly moistened and the reactive film containing solids is applied to the membrane while it is still moist. Membranes produced in this manner can contain reactive films having a high proportion of film openers and can be used advantageously in diagnostic elements for detecting constituents and, in particular, large hydrophobic analytes in body fluids.

Abstract: A method for applying reactive films containing solids to microporous membranes is provided wherein the membrane is firstly moistened and the reactive film containing solids is applied to the membrane while it is still moist. Membranes produced in this manner can contain reactive films having a high proportion of film openers and can be used advantageously in diagnostic elements for detecting constituents and, in particular, large hydrophobic analytes in body fluid.

Abstract: A method for applying reactive films containing solids to microporous membranes is provided wherein the membrane is firstly moistened and the reactive film containing solids is applied to the membrane while it is still moist. Membranes produced in this manner can contain reactive films having a high proportion of film openers and can be used advantageously in diagnostic elements for detecting constituents and, in particular, large hydrophobic analytes in body fluid.

Abstract: The invention concerns a system for the storage and transport of sample material on absorbent material which is characterized in that the system contains no test reagents and it additionally includes a closable container containing a medium that can absorb moisture such as a desiccant in addition to the absorbent material for absorbing a liquid sample. Furthermore the system according to the invention can contain an agent to stabilize the sample material and optionally further auxiliary substances.

Abstract: Device for the isolation of nucleic acids from a liquid sample by introducing the liquid into the device through an inlet opening and passage of the sample through a nucleic acid binding material and discharging of the resulting liquid through an outlet opening, wherein the nucleic acid binding material is inserted through the outlet opening during the manufacture of the device and the outlet opening is narrowed in order to hold the material. The device is particularly simple and reliable to manufacture but yet ensures that nucleic acids can be isolated without contamination.

Abstract: Device for the isolation of nucleic acids from a liquid sample by introducing the liquid into the device through an inlet opening and passage of the sample through a nucleic acid binding material and discharging of the resulting liquid through an outlet opening, wherein the nucleic acid binding material is inserted through the outlet opening during the manufacture of the device and the outlet opening is narrowed in order to hold the material. The device is particularly simple and reliable to manufacture but yet ensures that nucleic acids can be isolated without contamination.

Abstract: The subject of the invention is an article for collecting and transporting a sample to be analyzed; containing an absorbent matrix to absorb a liquid sample, characterized in that the absorbent matrix represents the sample collecting area of a sample collecting element, which is an integral part of an envelope. In addition, the subject of the invention is a process for determining an analyte, in which liquid sample material is placed on an absorbent matrix, dried, sent to a laboratory and tested there, characterized in that the liquid sample material is placed on an absorbent matrix that represents the sample collecting area of a sample collecting element, which is an integral part of an envelope.

Abstract: A sample application zone and detection zone are arranged on a pile-like complex made of a fleece and a porous membrane which are in a direct or indirect contact that enables passage of liquid through the contact area and the membrane is a polyamide, polyvinylidene difluoride, polyether sulfone or polysulfone membrane which transports liquid significantly slower over the area than the fleece.

Abstract: Disclosed is an element for collecting, transporting and storing sample material to be analyzed containing absorptive matrix material. The element contains a first and a second layer of absorptive matrix material which are arranged side by side, next to, and touching one another on an inert support material in a contact enabling liquid transfer in such a manner that liquid can pass from the first into the second layer when the first layer is filled with liquid. The first layer can be completely separated from the second layer after applying and drying the sample material. Also disclosed is a system containing such an element and a closable envelope in which the element can be transported. In addition, the invention concerns a method for analyzing a liquid sample material in which the liquid sample material is applied to an element according to the invention, the first layer is separated from the second layer of absorptive matrix material for analysis and is subsequently eluted.

Abstract: An adsorber material for collecting, concentrating and/or recovering gaseous and/or particle-shaped trace substances from an air or gas flow, in which the adsorber material is composed of fibrous elements made of natural and/or synthetic, organic, textile fibers which are worked into a nonwoven web having a planar geometry, the nonwoven web having a thickness of between 100 .mu.m and 2 mm and a weight per unit area of between 20 and 200 g/m.sup.2. Preferably the fibers have a fiber size between 1 and 10 dtex and are composed of cellulose and/or polyester, and if desired, the fibers may be provided with a binding agent and/or a moisture resistance agent. In preferred embodiments the nonwoven adsorber web is a fiber mixture of 80 parts polyester fibers, 20 parts viscose rayon staple fibers, and 20 parts polyvinyl alcohol fibers or a fiber mixture of 50 parts viscose rayon staple fibers and 50 parts linters, which are provided with an epichlorohydrin resin binder.

Abstract: Device for the determination of analytes having a sample application point, several separate sample withdrawal zones that are each connected with the sample application point by one capillary transport path and that have several test elements for the individual determination of analytes wherein a retardation zone is provided on at least one of the transport paths. Material for the capillary transport of a liquid sample defines a sample application zone and a plurality of sample withdrawal zones connected to said application zone by a like plurality of transport paths. At least one of said paths has a retardation zone which assures that liquid applied to said application zone arrives simultaneously at said withdrawal zones, regardless of the lengths of the paths.

Abstract: An analytical device is used for the determination of an analyte in a liquid sample. The device includes a fleece layer including fleece material and polyester fibers, and a reagent for determining an analyte. The reagent is for entering into a detectable reaction with the analyte. The polyester fibers are heat-meltable copolyester fibers containing terephthalic acid, isophthalic acid, and 1,4-butanediol.

Abstract: An analytical device determines the analytes in a liquid sample. This device includes a layer of flat material which has a sample application area and a detection area thereupon. The detection area includes a reagent for determining the analyte, and the absorbent sample application area and the absorbent detection area are disposed within a liquid impermeable boundary. The layer of flat material also includes an absorbent connector which is disposed such that the sample application area and the detection area are connected by the absorbent connector. The liquid impermeable boundary and the absorbent connector prevents liquid from being transported between the sample application area and the detection area, except through the absorbent connector.

Abstract: A carrier matrix of polyvinyl alcohol-coated glass is dissolvably impregnated with reagent. The matrix is manufactured by slurrying glass fibers in an excess of water and polyvinyl alcohol and forming a layer, which is then dried and impregnated with reagent.

Abstract: The invention concerns a device and its use for separating plasma from whole blood by means of a fibre-containing layer which contains an erythrocyte-aggregating substance and is characterized in that the fibre-containing layer contains glass fibres which are coated with polyvinyl alcohol or with polyvinyl alcohol/polyvinyl acetate. The invention also concerns a test carrier for the determination of a blood component as well as a process for separation from whole blood in which the device according to the present invention is used.

Abstract: The present invention provides an immune reactive porous carrier material comprising a porous carrier material with immune complexes precipitated thereon, wherein the porous carrier material is treated with at least one wet-strength agent.The present invention also provides processes for the production of this immune reactive porous carrier material.

Abstract: Test carrier for analysis of a sample liquid with the help of a specific binding reaction of two bioaffine binding partners, one of which is contained in the sample and one in the reagent system of the test carrier, with several capillary-active test zones (11-16; 21-25) arranged substantially next to one another on a base layer (2). The test zones are in liquid contact with one another so that they form a liquid transport path (20, 30) along which a liquid flows, driven by capillary forces, from a start zone (11, 21), a reaction thereby taking place between the first binding partner and the reagent system containing the second reaction partner, which reaction leads to a labelled species characteristic for the desired analysis.

Abstract: A carrier fleece is prepared for use as reagent carrier from which reagents can be dissolved in as assay such as immunological analysis. The carrier fleece contains from 5 to 60% by weight of cellulose-containing fibers, from 40 to 95% by weight of polyester or polyamide polymer fibers or a combination thereof and from 5 to 30% by weight of the fibers of an organic binding agent which has a hydroxyl or an ester group or a combination thereof. In an immunological analysis, the carrier fleece is impregnated with an immunologically active agent such as a beta-galactosidase conjugate and then introduced into a solution of a sample containing an immunologically active substance to be analyzed. The immunologically active agent is eluted into the sample solution and the presence of the immunologically active substance in the sample is determined.

Abstract: The present invention provides a test carrier for the analytical determination of a component of a sample liquid with the help of immunological reagents having a conjugate layer (2, 12), which contains a soluble conjugate of a first immunological binding partner with a labelling, a porous fixing layer (3, 13), which contains a second binding partner in carrier-fixed form binding specifically with the first binding partner, and an optical detection layer (8, 18), wherein the fixing layer (3, 13) is constructed in such a manner that the suction speed with which the liquid is transported in it is so high that the time needed for the spreading out of the liquid in the fixing layer is considerably shorter than the incubation time which is needed for the completion of the specific binding reaction between the first binding partner and the second binding partner and the optical detection layer (8, 18) is so fixed on the test carrier (1, 11) that, in a first position, it is not in contact with the fixing layer (3, 13