Abstract: The present invention relates to a compound according to general formula (I), which exhibits bioactivity; methods for the production of the compound; to pharmaceutical compositions comprising one or more of the compound(s); and to the use of the compound(s) as a medicament.

Abstract: A turbomachine may include a turbine arranged in a housing and configured to be acted on with a hot working medium. The turbomachine may include at least one bypass channel for heating the housing through the working medium. The bypass channel may extend completely within the housing and be configured to bypass the turbine.

Abstract: The present invention provides a tomaymycin biosynthetic gene cluster of Streptomyces species FH6421, and its use for producing 11-de-O-methyltomaymycm.

Abstract: The present invention relates to novel derivatives of cystobactamides of formula (Ib) and the use thereof for the treatment or prophylaxis of bacterial infections.

Abstract: A method is provided for optimizing the time required for a scale to weigh a set of ingredients. A weighing tolerance is obtained for each ingredient in the set. Based on the weighing tolerance, a readability parameter is determined for each ingredient. Based on the determined readability parameter, the scale is configured before each ingredient is weighed.

Abstract: A method for autofocusing a microscope at a correct autofocus position in a sample includes the steps: generating a reference pattern by an autofocus light device, projecting the reference pattern towards a sample, whereby the reference pattern is backscattered by at least two interfaces being located at or close to the sample, projecting the backscattered reference pattern towards a detector which provides spatial resolution, obtaining a superposition of a number of detection patterns, each detection pattern related to one of the interfaces, on the detector, analyzing the superposition of detection patterns to identify at least one autofocus detection pattern related to at least one of the interfaces, and analyzing the at least one autofocus detection pattern to determine the direction and/or magnitude of deviation of the microscope's current focus position from the correct focus position.

Abstract: The present invention provides a tomaymycin biosynthetic gene cluster of Streptomyces species FH6421, and its use for producing 11-de-O-methyltomaymycin.

Abstract: A method for depositing wet printed sheets and forming a sheet stack in a delivery of a printing machine. An auxiliary stack which is separate from the sheet stack has sheet-shaped intermediate layers that are usable as moisture barriers in the sheet stack. A plurality of sheets are stacked on top of one another to form a first section of the sheet stack. Then an intermediate layer is moved from the auxiliary stack onto the section of the sheet stack. A plurality of sheets are stacked on top of one another and on the intermediate layer to form a further section. The intermediate layer is thus arranged in the sheet stack between the first section and the further section. The placement of the intermediate layers provides a way of reducing or even eliminating quality losses in sheets and/or sheet stacks caused by moisture and moisture exchange.

Abstract: The present invention provides a method for the treatment or prophylaxis of bacterial infections by administering to a subject in need thereof an effective amount of a compound of formula.

Abstract: A core ring for an impeller or turbine of a torque converter is provided. The core ring includes an annular base portion including a convex blade side surface portion and a concave stator side surface portion and a wrapped outer diameter portion including an outwardly extending lip protruding radially outward from the annular base portion. A method of forming a torque core ring for an impeller or turbine of a torque converter is also provided. The method includes forming a wrapped outer diameter portion including an outwardly extending protrusion protruding radially outward from an annular base portion including a convex blade side surface portion and a concave stator side surface portion. A torque converter including the core ring is also provided.

Abstract: A method prints and dries a substrate where ink containing water and pigment is printed onto the substrate in an inkjet printing process. The substrate has an initial moisture content and absorbs at least water of the ink, causing the moisture content of the substrate to rise. Radiation selectively acting on the water molecules is applied in a first drying step and then radiation selectively acting on the pigment is applied in a second drying step in such a way that after completion of the two drying steps, the water of the applied ink has essentially completely evaporated and the substrate has essentially reattained its initial moisture content. In this manner optimum drying of substrates to which ink has been applied occurs.

Abstract: A vehicle may include an internal combustion engine configured to drive a plurality of wheels of the vehicle via a drive train. A waste heat utilization device may drive an electric generator by converting the waste heat generated by the internal combustion engine. The generator may be electrically connected to an on-board electrical system comprising an electric energy store and at least one electric consumer. An electric motor may be coupled to the drive train to provide an additional drive. The generator may convert kinetic energy generated by the waste heat utilization device into electrical energy and to provide the electrical energy to the on-board electrical system and/or to the electric motor. The electric motor may convert electrical energy provided by the electric energy store of the on-board electrical system and/or by the generator into kinetic energy and may couple the same into the drive train.

Abstract: A digital printing machine includes a first cylinder for transporting sheets, a second cylinder for transferring the sheets directly to the first cylinder, a third cylinder for transferring the sheets directly to the second cylinder, and at least one inkjet print head directed towards the first cylinder for printing on the sheets disposed thereon. At least one first sensor measures the temperature of the first cylinder, a second sensor measures the temperature of the sheets while being transported by the second cylinder or by the third cylinder, and at least one temperature control device controls the temperature of the sheets prior to their transfer to the first cylinder. A control element adapts the temperature of the sheets to the temperature of the first cylinder. The first sensor, the second sensor and the temperature control device are connected to the control element.

Abstract: The present invention provides a method for producing ?-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.

Abstract: A device for transmitting rotational motions without contact may include an inner rotor with at least one inner-rotor magnet and an outer rotor with at least one outer-rotor magnet. The inner rotor and the outer rotor are magnetically coupled to one another and rotatable along a rotation direction about a common axis of rotation. The at least one inner-rotor magnet and/or the at least one outer-rotor magnet may have a magnetization that is at least one of diametric, radial, and lateral. The at least one inner-rotor magnet may have a different type of magnetization than the at least one outer-rotor magnet.

Abstract: The present invention provides cystobactamides of formula (I) and the use thereof for the treatment or prophylaxis of bacterial infections: R1—Ar1-L1-Ar2-L2-Ar3-L3-Ar4-L4-Ar5—R2??(I):

Abstract: Disclosed is a receptacle for accepting nutrient media, especially for bacterial cultures. Said receptacle comprises a dish and a lid that covers the dish. The dish and the lid each have a circular bottom (dish bottom and lid bottom) and an annular wall (dish wall and lid wall) that projects from the bottom. One of the walls, preferably the lid wall, has an at least slightly larger internal diameter than the external diameter of the other wall, preferably the dish wall, such that one wall can be slid onto the other wall to close the dish. In order to be able to safely handle the receptacle, engaging means which prevent the dish and the lid from being accidentally released when the same are mutually engaged, are associated with the dish and the lid.

Abstract: A method for setting up and carrying out a print job on an inkjet printing machine having print heads and a thermal dryer includes printing onto a substrate using water-based black and chromatic inks. First test prints of a first test chart with different area coverage test patches are generated on the substrate using black ink, thermally drying the first test prints at different temperatures and evaluating dried first test prints to determine a dryer operating temperature during the print job. A second test print of a second test chart with different ink amount test patches is generated on the substrate using chromatic inks, thermally drying the second test print at the temperature, and evaluating the dried second test print to determine a total ink amount for operating the print heads during the print job. The machine receives temperature and total ink amount and prints the print job.

Abstract: A method of operating a battery system for providing electric energy to a vehicle. Sensor signals representing physical quantities of individual cells and/or individual modules of at least one battery of the battery system are generated. The sensor signals are transferred to a first and a second system controller. Both the first and second system controller evaluates the sensor signals and controls the battery system, depending on corresponding evaluation results. The first system controller is operated in combination with a first monitoring device and the second system controller is operated in combination with a second monitoring device. The first monitoring device monitors an operation of the second system controller and the second monitoring device monitors an operation of the first system controller. Depending on monitoring results of the first monitoring device and of the second monitoring device, the battery system is controlled.

Abstract: A vehicle may include an internal combustion engine configured to drive a plurality of wheels of the vehicle via a drive train. A waste heat utilization device may drive an electric generator by converting the waste heat generated by the internal combustion engine. The generator may be electrically connected to an on-board electrical system comprising an electric energy store and at least one electric consumer. An electric motor may be coupled to the drive train to provide an additional drive. The generator may convert kinetic energy generated by the waste heat utilization device into electrical energy and to provide the electrical energy to the on-board electrical system and/or to the electric motor. The electric motor may convert electrical energy provided by the electric energy store of the on-board electrical system and/or by the generator into kinetic energy and may couple the same into the drive train.