Patents by Inventor Rolf Müller

Rolf Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant preparation of selected bromelain fractions
    Patent number: 8409840
    Abstract: The present invention pertains in general to Bromelain and particularly to the different active compounds contained in this complex mixture of proteins. The present invention provides recombinant expressed cysteine proteases, which are found in Bromelain. It has been found that the method for expression of the recombinant proteins is superior to the purification from Bromelain itself.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: April 2, 2013
    Assignee: Ursapharm Arzneimittel GmbH
    Inventors: Rolf Müller, Nora Luniak, Klaus Eschmann
  • Synthetic pathway enzymes for the production of argyrins
    Patent number: 8404462
    Abstract: The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes participating in the production of Argyrins, as well as genetically manipulated micro-organisms containing nucleic acid sequences encoding the synthetic pathway enzymes for the production of Argyrins, e.g. for inserting one or more of these coding sequences, mutating in a targeted manner one or more of these nucleic acid sequences, in a wild type producer micro-organism or in a heterologous micro-organism, for the production of Argyrins.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: March 26, 2013
    Assignees: Helmholtz-Zentrum Fuer Infektionsforschung GmbH, Universitaet des Saarlandes
    Inventors: Rolf Müller, Silke Wenzel, Ronald Garcia
  • Stamped centering plate
    Patent number: 8371116
    Abstract: The invention relates to a stamped centering plate (10) for a torque converter with a first annular surface (12) having at least one arcuate slot (16), a second annular surface (14) opposite the first annular surface, and at least one arcuate segment (20) axially protruding downward from the second annular surface. The slot has an inner radius and an outer radius, the segment has an inner radius and an outer radius, and at least one of the slot radii is equal to at least one of the segment radii. In an example embodiment of the invention, the segment comprises material displaced to form the slot.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: February 12, 2013
    Assignee: Schaeffler Technologies AG & Co. KG
    Inventors: Rolf A. Mueller, Randy L. Keller
  • Polymer networks
    Patent number: 8202929
    Abstract: Polymer mixtures containing a first long-chain polymer and a second short-chain polymer. The structural parameters of the two polymers are coordinated in such a way that a polymeric material is obtained which is easier to process while being provided with improved mechanical properties and in part also improved thermal properties compared with the first polymer at suitable conditions for producing the polymer mixture as a result of networks being formed and heterocrystallization taking place.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: June 19, 2012
    Assignee: InnoGEL AG
    Inventors: Rolf Müller, Federico Innerebner
  • SHEET PROCESSING MACHINE, IN PARTICULAR SHEET-FED PRINTING PRESS AND METHOD OF DRYING SHEETS
    Publication number: 20120137537
    Abstract: A sheet processing machine, in particular a sheet-fed printing press, includes a varnishing unit and at least one combination drier for applying radiation energy and heated air to a newly varnished sheet. The at least one combination drier includes a plurality of circular or polygonal air nozzles and narrow-band high-power infrared light sources disposed between the air nozzles. The infrared light sources apply radiation at a radiation density of at least 25 kW/m2 in total to the varnished sheet. The temperature of the heated air passing through the nozzles is below 100° C., preferably below 80° C. A method of drying sheets is also provided.
    Type: Application
    Filed: December 5, 2011
    Publication date: June 7, 2012
    Applicant: HEIDELBERGER DRUCKMASCHINEN AG
    Inventors: JOCHEN JUNG, UWE ERNST, ROLF MÜELLER
  • CHARGE AIR DUCT FOR AN INTERNAL COMBUSTION ENGINE
    Publication number: 20120097136
    Abstract: A charge air duct for an internal combustion engine includes a housing with at least one entrance and at least one exit for charge air. A heat exchanger is arranged inside the housing to cool the charge air, a bypass is arranged on the housing to at least partially circumvent the heat exchanger and an actuator is arranged on the housing to influence the charge air flow. The charge air is guided from the entrance to the heat exchanger in a first position of the actuator and from the entrance to the bypass in a second position of the actuator, and the actuator at least partially reduces a cross-section of the charge air in a third position.
    Type: Application
    Filed: October 17, 2011
    Publication date: April 26, 2012
    Inventors: Johannes DIEM, Rolf MUELLER, Gunther HENTSCHEL, Bernhard HUURDEMAN, Karl-Ernst HUMMEL, Ulrich DEHNEN, Achim REHMANN
  • METHOD FOR CODING/INDIVIDUALIZING A CONTAINER USED TO RECEIVE NUTRIENT SOLUTIONS OR CULTURE MEDIA
    Publication number: 20120055993
    Abstract: A method for coding/individualizing a container used to receive nutrient solutions or culture media, in particular for cultivating microorganisms, cell cultures, bacteria and the like, the container being assigned a code, characterized in that the code is designed to be machine-readable, issued by the manufacturer and assigned to the container and that on the user side the code is assigned to a process as a data record.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 8, 2012
    Applicant: HEIPHA GMBH
    Inventor: Rolf Müller
  • STAMPED CENTERING PLATE
    Publication number: 20120055754
    Abstract: The invention relates to a stamped centering plate (10) for a torque converter with a first annular surface (12) having at least one arcuate slot (16), a second annular surface (14) opposite the first annular surface, and at least one arcuate segment (20) axially protruding downward from the second annular surface. The slot has an inner radius and an outer radius, the segment has an inner radius and an outer radius, and at least one of the slot radii is equal to at least one of the segment radii. In an example embodiment of the invention, the segment comprises material displaced to form the slot.
    Type: Application
    Filed: November 14, 2011
    Publication date: March 8, 2012
    Applicant: SCHAEFFLER TECHNOLOGIES GMBH & CO. KG
    Inventors: Rolf A. Mueller, Randy L. Keller
  • SHEET-PROCESSING MACHINE WITH ONE OR MORE DRYERS AND METHOD FOR DRYING SHEETS
    Publication number: 20120005917
    Abstract: A sheet-processing machine includes at least one dryer, air feed devices for the dryers, at least one air extraction device for heated exhaust air and a mixing device for mixing warm dryer exhaust air with the dryer feed air. An open loop or closed loop control device controls or regulates an extent to which the dryer exhaust air is mixed with the dryer feed air by using measured variables or setting values which are correlated with the moisture content of the exhaust air. A method for drying printed and/or varnished sheets is also provided.
    Type: Application
    Filed: July 7, 2011
    Publication date: January 12, 2012
    Inventors: JOCHEN JUNG, ROLF MUELLER
  • PRODUCTION OF OMEGA-3 FATTY ACIDS BY MYXOBACTERIA
    Publication number: 20110275846
    Abstract: The present invention provides a method for producing ?-3 polyunsaturated fatty acids by culturing specific myxobacterial stains and myxobacterial strains suitable for said method.
    Type: Application
    Filed: December 1, 2009
    Publication date: November 10, 2011
    Applicant: INTERMED DISCOVERY GMBH
    Inventors: Ernst Roemer, Rolf Müller, Ronald O. Garcia, Mark Stadler, Dominik Pistorius, Alexander Brachmann
  • BIOACTIVE PRE-TUBULYSINS AND USE THEREOF
    Publication number: 20110245295
    Abstract: The invention relates to bioactive pre-tubulysin derivatives, their preparation and pharmacological use.
    Type: Application
    Filed: September 22, 2009
    Publication date: October 6, 2011
    Applicant: UNIVERSITAT DES SAARLANDES
    Inventors: Yi Chai, Angelika Ullrich, Uli Kazmaier, Rolf Müller
  • RECOMBINANT PREPARATION OF BROMELAIN INHIBITORS AND BROMELAIN INHIBITOR PRECURSOR
    Publication number: 20110200541
    Abstract: The present invention pertains in general to Bromelain and particularly to the active compounds contained in this complex mixture of proteins. The present invention provides recombinant expressed Bromelain inhibitor precursor and Bromelain inhibitors, which are found in Bromelain. It has been found that the recombinant expressed inhibitors have superior effects in terms of treatment of disorders and conditions than Bromelain or its protein fractions from plant extracts.
    Type: Application
    Filed: July 27, 2009
    Publication date: August 18, 2011
    Applicant: Ursapharm Arzneimittel GmbH
    Inventors: Rolf Müller, Nora Luniak, Klaus Eschmann
  • SYNTHETIC PATHWAY ENZYMES FOR THE PRODUCTION OF ARGYRINS
    Publication number: 20110159537
    Abstract: The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes participating in the production of Argyrins, as well as genetically manipulated micro-organisms containing nucleic acid sequences encoding the synthetic pathway enzymes for the production of Argyrins, e.g. for inserting one or more of these coding sequences, mutating in a targeted manner one or more of these nucleic acid sequences, in a wild type producer micro-organism or in a heterologous micro-organism, for the production of Argyrins.
    Type: Application
    Filed: June 15, 2009
    Publication date: June 30, 2011
    Applicants: Universitat des Saarlandes, Helmholtz-Zentrum fur Infektionsforchung GmbH
    Inventors: Rolf Müller, Silke Wenzel, Ronald Garcia
  • BLADE ASSEMBLY WITH IMPROVED JOINT STRENGTH
    Publication number: 20110150656
    Abstract: A blade assembly for a torque converter including a shell with an inner surface and a plurality of blades attached to the shell by brazing. Each blade has a first surface for guiding a fluid in the torque converter and a second surface substantially parallel to the inner surface. The blades may include sheet steel and may be made by stamping. In an example embodiment of the invention, each blade includes at least one tab, the shell comprises a plurality of slots or indents, and the at least one tab is disposed in a respective slot or indent. The shell may be an outer shell or a core ring for a pump or turbine for the torque converter.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 23, 2011
    Applicant: SCHAEFFLER TECHNOLOGIES GMBH & CO. KG
    Inventors: Steven Olsen, Rolf A. Mueller
  • Method for determining operating parameters of a printing press
    Patent number: 7954431
    Abstract: A printing press, in particular a sheet-fed offset printing press, includes at least one control device, a plurality of printing units, one or more varnishing units, and one or more dryers. Variables determining a dryness of the printing material are determined and used to optimize the drying process. For that purpose, the important material streams influencing the drying process are determined at least for the region of the printing press that contains the drying device(s).
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: June 7, 2011
    Assignee: Heidelberger Druchmaschinen AG
    Inventors: Jochen Jung, Rolf Müller, Michael Rohleder, Matthias Niedernhuber
  • POLYSACCHARIDE BASED NETWORK AND METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20110124777
    Abstract: The production of polysaccharide networks, especially starch networks, having a high network density, high solidity, a low swelling degree, and exhibiting reduced water absorption and to the uses thereof, especially, in the filed of biodegradable plastics.
    Type: Application
    Filed: October 18, 2010
    Publication date: May 26, 2011
    Applicant: INNOGEL AG
    Inventors: Rolf Müller, Federico Innerebner, Paul Smith, Theo A. Tervoort
  • SLOWLY DIGESTIBLE STARCH PRODUCT
    Publication number: 20110117265
    Abstract: The invention relates to a starch product in the form of a foodstuff ingredient and to a foodstuff per se whose hydrolysis speed during digestion can be set to low and especially almost constant in that the starch is obtained as a partially crystalline network with a low degree of swelling by means of targeted conditioning, starting from an at least partly amorphous state.
    Type: Application
    Filed: November 11, 2010
    Publication date: May 19, 2011
    Applicant: INNOGEL AG
    Inventors: Rolf Müller, Federico Innerebner
  • Polysaccharide based network and method for the production thereof
    Patent number: 7943765
    Abstract: The production of polysaccharide networks, especially starch networks, having a high network density, high solidity, a low swelling degree, and exhibiting reduced water absorption and to the uses thereof, especially, in the field of biodegradable plastics.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: May 17, 2011
    Assignee: Innogel AG
    Inventors: Rolf Müller, Federico Innerebner, Paul Smith, Theo A. Tervoort
  • NUCLEUS REPLACEMENT BASED ON INJECTABLE PVA GELS
    Publication number: 20110077684
    Abstract: The invention relates to novel polyvinyl alcohol (PVA) gels which gelate in situ and are suitable for nucleus (gel bodies of the intervertebral disks) replacement, and to a process and to an apparatus for administration thereof, to the use thereof and to a vessel which comprises an inventive PVA gel.
    Type: Application
    Filed: May 27, 2009
    Publication date: March 31, 2011
    Applicant: Innogel AG
    Inventors: Rolf Mueller, Federico Innerebner, Thomas Steffen, Norbert Boos
  • Hair Coloring Agent Applicator
    Publication number: 20110005546
    Abstract: The present invention relates to an applicator (1) having an applicator element (8) for applying a product, conveyed to the application zone (5) from a separate reservoir, onto a strand of hair or of fibers comparable therewith, and having a strand gripper (12) movable back and forth between a closed position and a opened position. A strand gripper (12) of this kind serves to select and subsequently guide the hair or strands during actual product application. For improved guidance of the hair or strands during product application, the strand gripper (12) comprises a guidance surface (13) that, with the gripper (12) in the closed position, entirely overlaps the application zone (5) and holds the strand in contact with the application zone (5), by preference presses it onto the application zone (5).
    Type: Application
    Filed: July 7, 2010
    Publication date: January 13, 2011
    Inventors: Rolf Müller-Grünow, Manuela Geuther