Patents by Inventor Rolf Müller

Rolf Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single-chain multiple antigen-binding molecule, its preparation and use
    Patent number: 7838637
    Abstract: The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.
    Type: Grant
    Filed: June 30, 2004
    Date of Patent: November 23, 2010
    Assignee: Affitech Research AS
    Inventors: Roland Kontermann, Hans-Harald Sedlacek, Rolf Mueller
  • Adjustable magnetic idle station transport mechanism
    Patent number: 7832548
    Abstract: An idle station transport mechanism for a press, including a first plurality of magnetizable transport rails; a second plurality of magnetizable transport rails axially displaceable with respect to the first plurality of transport rails; and a plurality of transfer bars magnetizable to engage the material. The first and second pluralities of rails form a transport path along which material to be manipulated by the press is arranged to be transported and the transfer bars are displaceable to move the material axially along the transport path. In some aspects, the second plurality of transport rails is automatically displaceable while in the press, the plurality of transfer bars is arranged to magnetically engage a bottom side of the material, or the first and second pluralities of transport rails and the plurality of transfer bars are electro-magnetic. Also, a method of transporting material to a press.
    Type: Grant
    Filed: January 15, 2008
    Date of Patent: November 16, 2010
    Assignee: Luk Lamellen und Kupplungsbau Beteiligungs KG
    Inventors: Rolf A. Mueller, Douglas Jackson, Destery L. Pumphrey
  • RECOMBINANT PREPARATION OF SELECTED BROMELAIN FRACTIONS
    Publication number: 20100272659
    Abstract: The present invention pertains in general to Bromelain and particularly to the different active compounds contained in this complex mixture of proteins. The present invention provides recombinant expressed cysteine proteases, which are found in Bromelain. It has been found that the method for expression of the recombinant proteins is superior to the purification from Bromelain itself.
    Type: Application
    Filed: August 8, 2008
    Publication date: October 28, 2010
    Applicant: URSAPHARM ARZNEIMITTEL GMBH
    Inventors: Rolf Müller, Nora Luniak, Klaus Eschmann
  • INTAKE PIPE FOR A COMBUSTION ENGINE
    Publication number: 20100263637
    Abstract: Disclosed is an intake pipe for a combustion engine, comprising a housing (1) with a supply duct (2) for especially compressed air, a heat exchanger (8) which is disposed within a main duct (4) in the housing (1) and through which the air can flow in order to exchange heat with a fluid, and a bypass duct (5) that is separated from the main duct (4) in at least some sections and is fitted with at least one positioning element (7) to allow the fed air to adjustably bypass the heat exchanger (8). An end of the bypass duct (5) on the engine side is placed at a still flow-relevant short distance from an opening (11) of an intake valve (10) of the combustion engine.
    Type: Application
    Filed: August 20, 2008
    Publication date: October 21, 2010
    Inventors: Rolf Müller, Eberhard Pantow, Michael Spieth
  • METHOD FOR CONTROLLING PROCESS GAS CONCENTRATION
    Publication number: 20100215853
    Abstract: A method for controlling process gas concentration for treatment of substrates in a process space in which a medium is evaporated in a bubbler by bubbles of a carrier gas passed through the medium is achieved by producing a stipulated constant internal pressure in the bubbler and subsequent introduction of the carrier gas into the bubbler with simultaneous temperature control of the medium being evaporated within the bubbler to set a stipulated vapor pressure.
    Type: Application
    Filed: May 19, 2008
    Publication date: August 26, 2010
    Applicant: CENTROTHERM THERMAL SOLUTIONS GMBH + CO. KG
    Inventors: Hans Ulrich Voeller, Rolf Mueller, Robert Michael Hartung
  • Circuit arrangement for the cooling of charge air and method for operation of such a circuit arrangement
    Patent number: 7779791
    Abstract: The invention relates to a circuit arrangement (K), with a low-temperature coolant circuit (1) for the cooling of charge air on a motor vehicle with a charging device, comprising a charge air/coolant cooler (2). A temperature sensor (4) is provided at the exit of the coolant from the charge air/coolant (2), or directly thereafter, for the measurement of the coolant exit temperature. The invention further relates to a method for operation of such a circuit arrangement (K).
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: August 24, 2010
    Assignees: Behr GmbH & Co. KG, Behr Thermot-Tronik GmbH
    Inventors: Thomas Holzbaur, Rolf Müller, Eberhard Pantow, Sarah Parmentier, Eike Willers
  • Polyvinyl alcohol mixture gels
    Patent number: 7750055
    Abstract: Polyvinyl alcohol gels, particularly hydrogels, which are produced by methods and formulas and are provided with a characteristic profile that is adjustable to a large extent, e.g. outstanding mechanical properties with moduli of elasticity of 30 MPa and stiffnesses of 25 MPa at a breaking elongation of 550 percent, or full transparency in a wide range of water contents.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: July 6, 2010
    Assignee: InnoGEL AG
    Inventors: Rolf Müller, Federico Innerebner
  • RECEPTACLE FOR ACCEPTING NUTRIENT MEDIA
    Publication number: 20100093075
    Abstract: Disclosed is a receptacle for accepting nutrient media, especially for bacterial cultures. Said receptacle comprises a dish and a lid that covers the dish. The dish and the lid each have a circular bottom (dish bottom and lid bottom) and an annular wall (dish wall and lid wall) that projects from the bottom. One of the walls, preferably the lid wall, has an at least slightly larger internal diameter than the external diameter of the other wall, preferably the dish wall, such that one wall can be slid onto the other wall to close the dish. In order to be able to safely handle the receptacle, engaging means which prevent the dish and the lid from being accidentally released when the same are mutually engaged, are associated with the dish and the lid.
    Type: Application
    Filed: April 9, 2008
    Publication date: April 15, 2010
    Inventor: Rolf Müller
  • Polyvinyl alcohol gels, especially in situ gelling gels
    Patent number: 7674852
    Abstract: The invention relates to polyvinlyl alcohol gels which are suitable for use in the organism and which are formed at the site of application (in situ) from a viscous liquid by partial crystallization and network formation.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: March 9, 2010
    Assignee: Innogel AG
    Inventors: Rolf Müller, Federico Innerebner
  • APPLICATOR
    Publication number: 20100037910
    Abstract: The present invention relates to an applicator for applying a product onto keratin-containing fibers or fiber bunches, comprising at least one application element and at least one selection element.
    Type: Application
    Filed: October 25, 2007
    Publication date: February 18, 2010
    Applicant: HENKEL AG & CO. KGAA
    Inventors: Rolf Müller-Grünow, Andreas Wietzke
  • Arrangement for cooling exhaust gas and charge air
    Patent number: 7650753
    Abstract: The invention relates to an arrangement (A) for cooling recycled exhaust gas (AG) and charge air (LL) in a motor vehicle comprising a turbocharger respectively comprising at least one heat exchanger for the exhaust gas flow and a least one heat exchanger for the charge air flow. At least one heat exchanger for the exhaust gas flow and one heat exchanger for the charge air flow form part of a common low temperature cooling circuit (NK). The invention also relates to a method for operating one such arrangement (A).
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: January 26, 2010
    Assignee: BEHR GmbH & Co. KG
    Inventors: Rolf Müller, Eberhard Pantow
  • Hand-held power tool with a replaceable tool fitting
    Patent number: 7644929
    Abstract: A very easy-to-actuate, replaceable tool fitting is comprised in that at least one movably supported profiled body (15) on an output spindle (1) or on the tool fitting (11) of the hand-held power tool and at least one profiled recess (7) on the output spindle (1) or on the tool fitting (11) are shaped and situated in such a way that when the tool fitting (11) is slid onto the output spindle (1), the at least one profiled body (15) engages in detent fashion in the at least one profiled recess (7), achieving both an axial locking and a rotary driving of the tool fitting (11) in relation to the output spindle (1) and means (6, 8, 14) are provided, which, through a rotating and sliding motion of the tool fitting (11) on the output spindle (1), guide the profiled body (15) into the profiled recess (7).
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: January 12, 2010
    Assignee: Robert Bosch GmbH
    Inventors: Karl Frauhammer, Otto Baumann, Rolf Mueller, Heinz Schnerring, Dietmar Saur, Willy Braun, Axel Kuhnle, Thomas Bernhardt, Uwe Engelfried
  • Single-chain Multiple Antigen-binding Molecule, Its Preparation and Use
    Publication number: 20090326206
    Abstract: The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.
    Type: Application
    Filed: August 21, 2009
    Publication date: December 31, 2009
    Inventors: Roland Kontermann, Hans-Harald Sedlacek, Rolf Mueller
  • METHODS FOR HETEROLOGOUS EXPRESSION OF SECONDARY METABOLITES
    Publication number: 20090298117
    Abstract: The invention provides a method for the heterologous expression of a secondary metabolite encoded by a biosynthetic pathway. Also provided is a method for introducing a large sized DNA molecule into the chromosome of a heterologous host using a transposable element. Novel myxochromide S derivatives are also provided.
    Type: Application
    Filed: October 26, 2005
    Publication date: December 3, 2009
    Inventors: Youming Zhang, Rolf Müller, Francis Stewart, Frank Gross, Silke C. Wenzel, Jun Fu
  • VALVE FOR REGULATING AN EXHAUST GAS FLOW OF AN INTERNAL COMBUSTION ENGINE, HEAT EXCHANGER FOR EXHAUST GAS COOLING, SYSTEM HAVING AT LEAST ONE VALVE AND HAVING AT LEAST ONE HEAT EXCHANGER
    Publication number: 20090165449
    Abstract: The invention relates to a valve (1, VT1) for regulating an exhaust gas flow of an internal combustion engine having at least one closure element, having at least one actuator for actuating the closure element, and having at least one heat transfer duct (30, 36) for valve cooling, which heat transfer duct can be traversed by at least one first medium (M1).
    Type: Application
    Filed: February 12, 2007
    Publication date: July 2, 2009
    Inventors: Maren Christ, Rolf Müller
  • Device for driving a coolant pump
    Patent number: 7475764
    Abstract: The invention relates to a device for driving a coolant pump (2) for the coolant circuit of an internal combustion engine in a motor vehicle comprising a drive train that encompasses a drive wheel (7), a viscous coupling (11), and a drive shaft (3). The inventive driving device is provided with a second coupling (15) which is embodied as a clutch and can be connected to the drive train parallel to the viscous coupling (11), resulting in increased redundancy and two-step rev control.
    Type: Grant
    Filed: July 4, 2003
    Date of Patent: January 13, 2009
    Assignee: BEHR GmbH & Co. KG
    Inventors: Gerold Schultheiss, Peter Ambros, Rolf Müller, Rudolf Stoklossa
  • Method for frequency-driven generation of a multiresolution decomposition of the input to wave-based sensing arrays
    Patent number: 7423587
    Abstract: A method for generating a multiresolution decomposition of an array signal by a bank of spatial bandpass filters is disclosed. The signal processing operation is implemented through the use of the directivities of the individual array elements and does not degrade the spatial or temporal resolution of the array.
    Type: Grant
    Filed: April 2, 2006
    Date of Patent: September 9, 2008
    Inventor: Rolf Mueller
  • Adjustable magnetic idle station transport mechanism
    Publication number: 20080173520
    Abstract: An idle station transport mechanism for a press, including a first plurality of magnetizable transport rails; a second plurality of magnetizable transport rails axially displaceable with respect to the first plurality of transport rails; and a plurality of transfer bars magnetizable to engage the material. The first and second pluralities of rails form a transport path along which material to be manipulated by the press is arranged to be transported and the transfer bars are displaceable to move the material axially along the transport path. In some aspects, the second plurality of transport rails is automatically displaceable while in the press, the plurality of transfer bars is arranged to magnetically engage a bottom side of the material, or the first and second pluralities of transport rails and the plurality of transfer bars are electro-magnetic. Also, a method of transporting material to a press.
    Type: Application
    Filed: January 15, 2008
    Publication date: July 24, 2008
    Applicant: LuK Lamelln und Kupplungsbau Beteiligungs KG
    Inventors: Rolf A. Mueller, Douglas Jackson, Destery L. Pumphrey
  • Method for Frequency-Driven Generation of a MultiResolution Decomposition of the Input to Wave-Based Sensing Arrays
    Publication number: 20070229353
    Abstract: A method for generating a multiresolution decomposition of an array signal by a bank of spatial bandpass filters is disclosed. The signal processing operation is implemented through the use of the directivities of the individual array elements and does not degrade the spatial or temporal resolution of the array.
    Type: Application
    Filed: April 2, 2006
    Publication date: October 4, 2007
    Inventor: Rolf Mueller
  • Liposomes and liposomal compositions for vaccination and drug delivery
    Publication number: 20070148220
    Abstract: The present invention relates to liposomes and compositions comprising liposomes, their production and use for the prevention and therapy of proliferative diseases, infectious diseases, vascular diseases, rheumatoid diseases, inflammatory diseases, immune diseases, and allergies.
    Type: Application
    Filed: December 22, 2004
    Publication date: June 28, 2007
    Inventors: Rolf Müller, Andreas Graser, Abdo Konur, Sabine Muller-Brusselbach, Valerie Jerome