Patents by Inventor Ronald A. Smith

Ronald A. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11896068
    Abstract: A glove of a type worn to provide masking effect between a wear's hand and another surface, such as surface of food stuff. The glove, or fragments thereof, is rendered detectable by X-ray and/or metal detection apparatus. Apparatus and/or indication means can be provided to allow a detected glove or glove portion to be allocated to a particular location and/or personnel to allow, if necessary, remedial action to be taken.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: February 13, 2024
    Inventor: Sean Ronald Smith
  • Publication number: 20240025907
    Abstract: The present invention relates to compounds that inhibit at least one of KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: August 2, 2023
    Publication date: January 25, 2024
    Inventors: Xiaolun Wang, Anthony Ivetac, Svitlana Kulyk, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith
  • Patent number: 11871873
    Abstract: A manual food shredding device for shredding of a food item includes a base, an upright bowl, and an inverted bowl. The base is positionable on a substantially horizontal surface, such as a countertop. A food item can be positioned in the upright bowl, which is attached to an upper face of the base. A plurality of first spikes is attached to and extends from a bottom toward a top of the upright bowl. The inverted bowl is circumferentially larger than the upright bowl so that the upright bowl is selectively insertable into the inverted bowl. A plurality of second spikes is attached to and extends from an upper end toward a lower end of the inverted bowl. The inverted bowl can be grasped in a hand of a user and rotated by a user, thereby causing the first spikes and the second spikes to shred the food item.
    Type: Grant
    Filed: August 25, 2022
    Date of Patent: January 16, 2024
    Inventor: Ronald Smith
  • Patent number: 11841205
    Abstract: A gas piston according to various aspects of the present technology comprises a helical groove disposed along an exterior surface. The helical groove may comprise curved edges at transitions between a crest and root of the helical groove. The helical groove allows for easier movement of the gas piston within its operating cylinder, provides enhanced resistance to particulate build up, and improves firing accuracy.
    Type: Grant
    Filed: February 2, 2023
    Date of Patent: December 12, 2023
    Assignee: Smith Enterprise, Inc.
    Inventor: Ronald Smith
  • Patent number: 11839247
    Abstract: A glove of a form typically, although not necessarily exclusively, provided for single or limited use purposes and discarded thereafter. The glove is to prevent contact between a product and a person's hand and to avoid contamination. The glove material includes components capable of detection by at least one form of noncontact detection apparatus which renders the glove or portion detectable if discarded and inadvertently becomes part of a manufacturing process or product. The components render the glove detectable by using metal detection apparatus and/or X-ray detection apparatus which may allow removal of the glove. The glove may also include an antimicrobial agent as part to prevent or reduced contamination on the surface of the glove. The glove can also be rendered biodegradable.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: December 12, 2023
    Assignee: Detectamet Limited
    Inventor: Sean Ronald Smith
  • Publication number: 20230373999
    Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: October 21, 2022
    Publication date: November 23, 2023
    Inventors: Matthew Arnold MARX, James Gail CHRISTENSEN, Christopher Ronald SMITH, James F. BLAKE, Laurence E. BURGESS, Mark Joseph CHICARELLI, Adam COOK, Jay Bradford FELL, John P. FISCHER, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Pavel SAVECHENKOV, Tony P. TANG, Guy P.A. VIGERS
  • Publication number: 20230366644
    Abstract: A gas piston according to various aspects of the present technology comprises a helical groove disposed along an exterior surface. The helical groove may comprise curved edges at transitions between a crest and root of the helical groove. The helical groove allows for easier movement of the gas piston within its operating cylinder, provides enhanced resistance to particulate build up, and improves firing accuracy.
    Type: Application
    Filed: February 2, 2023
    Publication date: November 16, 2023
    Applicant: Smith Enterprise, Inc.
    Inventor: Ronald Smith
  • Publication number: 20230312482
    Abstract: The present invention relates to compounds that inhibit Son of sevenless homolog 1 (SOS1) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
    Type: Application
    Filed: July 27, 2021
    Publication date: October 5, 2023
    Inventors: Matthew Arnold Marx, John Michael Ketcham, Christopher Ronald Smith, John David Lawson, Anthony Ivetac
  • Publication number: 20230279025
    Abstract: The present invention relates to compounds that inhibit KRas G12D, In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: February 25, 2021
    Publication date: September 7, 2023
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James Francis Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • Patent number: 11702418
    Abstract: The present invention relates to compounds that inhibit Son of sevenless homolog 1 (SOS1) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: July 18, 2023
    Assignee: MIRATI THERAPEUTICS, INC.
    Inventors: Matthew Arnold Marx, John Michael Ketcham, Christopher Ronald Smith, John David Lawson, Aaron Craig Burns, Xiaolun Wang, Svitlana Kulyk, Anthony Ivetac
  • Publication number: 20230137886
    Abstract: The present invention relates to methods of treating cancer using compounds that inhibit Son of sevenless homolog 1 (SOS1) activity and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: November 29, 2022
    Publication date: May 4, 2023
    Inventors: Matthew Arnold Marx, John Michael Ketcham, Christopher Ronald Smith, John David Lawson, Aaron Craig Burns, Xiaolun Wang, Svitlana Kulyk, Anthony Ivetac
  • Publication number: 20230101312
    Abstract: The present invention relates to compounds that inhibit Son of sevenless homolog 1 (SOS1) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
    Type: Application
    Filed: February 23, 2021
    Publication date: March 30, 2023
    Inventors: Matthew Arnold Marx, John Michael Ketcham, Christopher Ronald Smith, John David Lawson, Aaron Craig Burns, Xiaolun Wang
  • Publication number: 20230077225
    Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: July 20, 2022
    Publication date: March 9, 2023
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • Publication number: 20230072276
    Abstract: The present invention relates to compounds that inhibit at least one of KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: December 15, 2021
    Publication date: March 9, 2023
    Inventors: Xiaolun Wang, Svitlana Kulyk, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith
  • Publication number: 20230054883
    Abstract: The present invention relates to compounds that inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.
    Type: Application
    Filed: September 12, 2022
    Publication date: February 23, 2023
    Inventors: Thomas P. Bobinski, Christopher Ronald Smith, Matthew Arnold Marx, John Michael Ketcham, Aaron Craig Burns, John David Lawson, Svitlana Kulyk, Jon Kuehler, Anthony Ivetac
  • Patent number: 11548888
    Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: January 10, 2023
    Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.
    Inventors: Matthew Arnold Marx, James Gail Christensen, Christopher Ronald Smith, John P Fischer, Aaron Craig Burns
  • Patent number: 11492351
    Abstract: The present invention relates to compounds that inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In particular, the present invention relates to compounds of Formula (I) to pharmaceutical compositions comprising compounds of Formula (I) and to methods of use thereof, such as methods of treating cancer using the compounds of Formula (I) and pharmaceutical compositions comprising those compounds.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: November 8, 2022
    Assignee: Mirati Therapeutics, Inc.
    Inventors: Thomas P. Bobinski, Christopher Ronald Smith, Matthew Arnold Marx, John Michael Ketcham, Aaron Craig Burns, John David Lawson, Svitlana Kulyk, Jon Kuehler, Anthony Ivetac
  • Patent number: 11479551
    Abstract: The present invention relates to compounds that inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In particular, the present invention relates to compounds of Formula (I) to pharmaceutical compositions comprising compounds of Formula (I) and to methods of use thereof, such as methods of treating cancer using the compounds of Formula (I) and pharmaceutical compositions comprising those compounds.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: October 25, 2022
    Assignee: Mirati Therapeutics, Inc.
    Inventors: Thomas P. Bobinski, Christopher Ronald Smith, Matthew Arnold Marx, John Michael Ketcham, Aaron Craig Burns, John David Lawson, Svitlana Kulyk, Jon Kuehler, Anthony Ivetac
  • Patent number: 11453683
    Abstract: Compounds that inhibit KRas G12D; in particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: September 27, 2022
    Assignees: MIRATI THERAPEUTICS, INC., ARRAY BIOPHARMA INC.
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P. A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • Patent number: 11423391
    Abstract: An electronic device may include circuitry and an anti-tamper device having a physical characteristic that changes in response to a tamper attempt. The circuitry is configured to determine physically unclonable function (PUF) data based on the physical characteristic and to perform at least one secure operation based on the PUF data. The circuitry is further configured to detect the tamper attempt based a change to the physical characteristic and to perform at least one action in response to detection of the tamper attempt for protecting the electronic device from the tamper attempt.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: August 23, 2022
    Assignee: Block, Inc.
    Inventors: Jeremy Wade, William Hardy, Malcolm Ronald Smith, Afshin Rezayee, Yue Yang