Patents by Inventor Ronald Albright

Ronald Albright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for treating pathological calcification conditions, and methods using same
    Patent number: 10064917
    Abstract: The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: September 4, 2018
    Assignee: Yale Unviersity
    Inventors: Demetrios Braddock, Ronald Albright
  • Compositions and methods for treating pathological calcification and ossification
    Patent number: 10052367
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 21, 2018
    Assignee: Yale University
    Inventors: Demetrios Braddock, Ronald Albright
  • Compositions and Methods for Modulating Coagulation
    Publication number: 20180169192
    Abstract: The present invention relates to compositions and methods for modulating coagulation through modulating the level or activity of NPP4.
    Type: Application
    Filed: December 4, 2017
    Publication date: June 21, 2018
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions and methods for treating pathological calcification and ossification
    Patent number: 9913881
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: March 13, 2018
    Assignee: Yale University
    Inventors: Demetrios Braddock, Ronald Albright
  • Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
    Publication number: 20180064786
    Abstract: The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 8, 2018
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
    Publication number: 20180057821
    Abstract: The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 1, 2018
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
    Publication number: 20180057820
    Abstract: The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 1, 2018
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions and methods for treating hemophilia
    Patent number: 9867870
    Abstract: The present invention relates to compositions and methods for modulating coagulation through modulating the level or activity of NPP4.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: January 16, 2018
    Assignee: Yale University
    Inventors: Demetrios Braddock, Ronald Albright
  • Compositions and Methods for Treating Pathological Calcification and Ossification
    Publication number: 20170354719
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Application
    Filed: August 25, 2017
    Publication date: December 14, 2017
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
    Publication number: 20170340713
    Abstract: The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.
    Type: Application
    Filed: August 9, 2017
    Publication date: November 30, 2017
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions for Treating Pathological Calcification Conditions, and Methods Using Same
    Publication number: 20170340714
    Abstract: The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological ossification. In certain embodiments, the diseases or disorders are selected from the group consisting of Generalized Arterial Calcification of Infancy (GACI), Idiopathic Infantile Arterial Calcification (IIAC), Ossification of the Posterior Longitudinal Ligament (OPLL), hypophosphatemic rickets, osteoarthritis, calcification of atherosclerotic plaques, PXE, hereditary and non-hereditary forms of osteoarthritis, ankylosing spondylitis, hardening of the arteries occurring with aging, calciphylaxis resulting from end stage renal disease and progeria.
    Type: Application
    Filed: August 9, 2017
    Publication date: November 30, 2017
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions and Methods for Treating Pathological Calcification and Ossification
    Publication number: 20170333533
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Application
    Filed: August 8, 2017
    Publication date: November 23, 2017
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions and Methods for Modulating Coagulation
    Publication number: 20170274054
    Abstract: The present invention relates to compositions and methods for modulating coagulation through modulating the level or activity of NPP4.
    Type: Application
    Filed: April 6, 2017
    Publication date: September 28, 2017
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions and Methods for Treating Pathological Calcification and Ossification
    Publication number: 20170252414
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 7, 2017
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Compositions and methods for treating pathological calcification and ossification
    Patent number: 9744219
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: August 29, 2017
    Assignee: Yale University
    Inventors: Demetrios Braddock, Ronald Albright
  • Compositions and methods for modulating coagulation
    Patent number: 9642896
    Abstract: The present invention relates to compositions and methods for modulating coagulation through modulating the level or activity of NPP4.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: May 9, 2017
    Assignee: Yale University
    Inventors: Demetrios Braddock, Ronald Albright
  • COMPOSITIONS AND METHODS FOR TREATING PATHOLOGICAL CALCIFICATION AND OSSIFICATION
    Publication number: 20150359858
    Abstract: The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological ossification by modulating the level or activity of NPP1 or a mutant thereof, or a mutant NPP4 modified to exhibit ATP hydrolase activity similar to the hydrolase activity of NPP1.
    Type: Application
    Filed: February 12, 2014
    Publication date: December 17, 2015
    Inventors: Demetrios BRADDOCK, Ronald ALBRIGHT
  • Method to etch chrome deposited on calcium fluoride object
    Publication number: 20050077267
    Abstract: A method for maintaining a micro-roughness finish after etching chrome from a surface of a calcium fluoride (CaF2) object. Etching the chrome a first amount in a first chrome etchant. Etching the chrome a second amount beyond the first predetermined amount in second chrome etchant, such that the CaF2 object maintains a low micro-roughness.
    Type: Application
    Filed: October 10, 2003
    Publication date: April 14, 2005
    Inventors: Nicholas DeLuca, Ronald Albright