Abstract: The present disclosure generally relates to oral care systems and devices. An oral care system includes a container defining an interior portion and a moveable funnel configured to slide in the interior portion of the container. The moveable funnel includes a funnel portion having a base connected to a tube, where a distal end of the tube includes a cutting edge angled relative to a central axis of the tube. The system further includes a toothbrush supported by the tube, the toothbrush having a handle extending out from the container.

Abstract: Methods to assess a pediatric subject having a single ventricle heart include identifying a difference between concentration levels of metabolic biomarkers and reference concentration levels and then assessing the pediatric subject based on the identified differences.

Abstract: A glass container for storing pharmaceutical formulations may include a glass body formed from a Type IA or Type IB glass composition according to ASTM Standard E438-92(2011). The glass body may include a wall portion with an inner surface and an outer surface, a heel portion and a floor portion, wherein the inner surface of the glass container is formed by the inner surface of the glass body. The glass body may include at least a class A2 base resistance or better according to ISO 695, at least a type HGB2 hydrolytic resistance or better according to ISO 719 and Type 1 chemical durability according to USP <660>. The glass container does not comprise a boron-rich layer on the inner surface of the glass body in as formed condition.

Abstract: A coated glass pharmaceutical package includes a glass body having a Type 1 chemical durability according to USP 660, at least a class A2 base resistance or better according to ISO 695, and at least a type HGB2 hydrolytic resistance or better according to ISO 719, the glass body having an interior surface and an exterior surface and a wall extending therebetween. A lubricous coating having a thickness of less than or equal to 90 nm may be positioned on at least a portion of the exterior surface of the glass body but not on any portion of the interior surface. The portion of the coated glass package with the lubricous coating comprises a coefficient of friction that is at least 20% less than an uncoated glass package and the coefficient of friction does not increase by more than 30% after undergoing a depyrogenation cycle including exposure to a temperature of 250° C. for a time period of 30 minutes.

Abstract: Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval.

Abstract: Provided are computing systems, methods, and platforms that automatically produce production-ready machine learning models and deployment pipelines from minimal input information such as a raw training dataset. In particular, one example computing system can import a training dataset associated with a user. The computing system can execute an origination machine learning pipeline to perform a model architecture search that selects and trains a machine learning model for the training dataset. Execution of the origination machine learning pipeline can also result in generation of a deployment machine learning pipeline configured to enable deployment of the machine learning model (e.g., running the machine learning model to produce inferences and/or optionally other tasks such as re-training and/or re-tuning the model).

Abstract: Particular embodiments described herein provide for an electronic device that can be configured to allow for the mitigation of ransomware. For example, the system can determine that an application begins to execute, determine that the application attempts to modify a file, determine a file type for the file, and create a security event if the application is not authorized to modify the file type. In another example, the system determines an entropy value between the file and the attempted modification of the file, and create a security event if the entropy value satisfies a threshold or determine a system entropy value that includes a rate at which other files on the system are being modified by the application, and create a security event if the system entropy value satisfies a threshold.

Abstract: A system and method for implementing and manufacturing a hierarchy system for use with a TMCCC-containing electrically-conductive structure (e.g., an electrode) as well as methods for use and manufacturing of such structures and electrochemical cells including these devices. Structures and methods include a coordination complex having LxMyNzTia1Va2Cra3Mna4Fea5Coa6Nia7Cua8Zna9Caa10Mga11[R(CN)6]b (H2O)c. The method includes binding electrochemically active material to produce a hierarchical structure, the hierarchical structure having a plurality of primary crystallites having a size D1, the plurality of these primary crystallites agglomerated into a set of agglomerates each agglomerate having a size D2>D1.

Abstract: The present disclosure relates to pharmaceutical compositions comprising PTEN inhibitors and methods of treating or preventing bone marrow loss in subjects in subjects in need thereof. The compositions and methods of this disclosure are useful in treating or preventing bone marrow loss associated with exposure to nuclear radiation or chemotherapeutic treatment.

Abstract: A cooling jacket for an electric motor comprises a fluid passage disposed adjacent to a stator and configured to convey a cooling fluid. The cooling jacket includes a flow mixing enhancer within the fluid passage adjacent an axial end of the stator. The flow mixing enhancer includes baffles, a porous fibrous structure, and/or an open-cell foam to provide greater thermal conductance at a region adjacent to the axial ends than it provides to a central region therebetween. A flow bridge directs the cooling fluid through circumferential flow paths adjacent to both of the axial ends before the cooling fluid is circulated in a central flow path around the central region of the stator. One or more nozzles direct a jet of cooling fluid upon the stator end winding, a rotor end winding, and/or printed circuit board. A ring-shaped coolant header may supply the cooling fluid to the nozzles.

Abstract: A coaxial wire interconnect architecture and associated methods are described. In one example, the coaxial wire interconnect architecture is used in a test socket interconnect array. Flexible bends are formed in one or more of the coaxial wire interconnects to provide compliant connections to an electronic device during testing.

Abstract: The disclosure relates to an eyepiece extender for an ophthalmic microscope, such as a slit lamp microscope. The eyepiece extender comprises certain lens designs and arrangements and provides ergonomic improvement to a user of the ophthalmic microscope and accommodates different magnifications, such as high and low magnifications, while preserving image fidelity for each magnification such that the image is essentially distortion free and color corrected in each magnification instance.

Abstract: A portable collapsible chair may include a frame that may be collapsed to enable a user to carry or store the chair and that may be expanded to form a chair on which the user may sit. The chair may further include a backrest coupled to the frame, a seat coupled to the frame, and one or more heat exchangers. The chair may also include a control circuit coupled to the one or more heat exchangers. The control circuit may provide a first signal to at least some of the one or more heat exchangers to warm the chair in a warming mode or may provide a second signal to at least some of the one or more heat exchangers to cool the chair in a cooling mode.

Abstract: Methods are provided for preparing a composition having a melt viscosity of between 160 Pas and 400 Pas, as determined according to ISO-11443-2014 at 270° C. and a shear rate of 265 1/s, and a volume resistivity of at most 105 Ohm·cm, measured according to ASTM D257 on an injection molded test sample of 3 mm thickness and a diameter of 50 mm and coated with a gold layer on an upper and lower surface and, as well as the composition itself and painted parts comprising the composition.

Abstract: This invention relates to a method for preparing a composition having a melt viscosity of between 160 Pas and 400 Pas, as determined according to ISO-11443-2014 at 270° C. and a shear rate of 265 l/s, and a volume resistivity of at most 105 Ohm·cm, measured according to ASTM D257 on an injection molded test sample of 3 mm thickness and a diameter of 50 mm and coated with a gold layer on an upper and lower surface and, as well as the composition itself and painted parts comprising the composition.

Abstract: An ophthalmic stimulator for temporarily constricting a pupil of an eye comprises an irradiation control system, having a feedback system, to generate an irradiation control signal using a feedback of the feedback system; an irradiation source, coupled to the irradiation control system, to generate an irradiation; and an irradiation delivery system, having a targeting system and coupled to the irradiation control system, to receive the irradiation from the irradiation source, and to direct a patterned irradiation in a pattern to a treatment region of an iris of the eye using the targeting system; wherein the irradiation control system controls at least one of the irradiation source and the irradiation delivery system with the irradiation control signal so that the patterned irradiation causes a temporary constriction of the pupil, without causing a permanent constriction of the pupil.

Abstract: A portable collapsible chair may include a frame that may be collapsed to enable a user to carry or store the chair and that may be expanded to form a chair on which the user may sit. The chair may further include a backrest coupled to the frame, a seat coupled to the frame, and one or more heat exchangers. The chair may also include a control circuit coupled to the one or more heat exchangers. The control circuit may provide a first signal to at least some of the one or more heat exchangers to warm the chair in a warming mode or may provide a second signal to at least some of the one or more heat exchangers to cool the chair in a cooling mode.

Abstract: A networked system of ophthalmic stimulators for temporarily constricting eye-pupils comprises a set of ophthalmic stimulators, each ophthalmic stimulator including a mobile irradiation control system, to generate an irradiation control signal; an irradiation source, coupled to the irradiation control system, to generate an irradiation; and an irradiation delivery system, coupled to the mobile irradiation control system, to receive the irradiation from the irradiation source, and to deliver a patterned irradiation to an iris of the eye; wherein the mobile irradiation control system controls at least one of the irradiation source and the irradiation delivery system with the irradiation control signal so that the patterned irradiation causes a temporary constriction of the pupil of the eye, without causing a permanent constriction of the pupil; and a central station, including a central image processor, wherein the mobile irradiation control systems and the central station are configured to communicate through

Abstract: A system is provided for loading one or more transport tank, the system including one or more load lines for connecting between on-site storage tanks or vessels and the transport tanks; one or more vapour return lines for connecting between the transport tanks and an on-site flare or downstream units; an oxygen deficient medium source; one or more oxygen deficient medium blend supply lines connectable to each of the vapour return lines; a HMI/PLC for automation and control of the operations of the system; and a control panel in communication with the HMI/PLC for starting and stopping operation of the system. Gases displaced from the transport tanks during loading can be sent directly to flare or downstream units. A method is also provided for loading a fluid from one or more on-site storage tanks or vessels to one or more transportation tanks.