Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

Abstract: An optical network transmitter comprising a fractional-bit delay module, an optical modulator coupled to the fractional-bit delay module, and a band-limiting optical filter coupled to the optical modulator. Also disclosed is a transmission system comprising a source configured to generate two complementary binary data streams, a fractional-bit delay module in communication with the source and configured to delay one of the complementary binary data streams, a modulation module in communication with the source and the fractional-bit delay module and configured to convert the undelayed complementary binary data streams and the delayed complementary binary data streams into a fractional-bit delayed optical duobinary signal, and a band-limiting node in communication with the modulation module and configured to filter and transmit the optical duobinary signal.

Abstract: A system and a method for allocating Sounding Reference Signal (SRS) resources are provided in the present invention, the method includes: an e-Node-B (eNB) allocating a SRS bandwidth with 4n Resource Blocks (RBs) to a terminal, and equally dividing a time domain sequence of a SRS into t portions in the SRS bandwidth; the eNB configuring a time domain RePetition Factor (RPF) used by the UE, and the eNB configuring the UE to use one or more cyclic shifts in L cyclic shifts for each UE; then the eNB notifying the UE of a value of the time domain RPF, a location of a used frequency comb and a used cyclic shift by signaling, wherein n is a positive integer; the RPF satisfies a following condition: 48 × n RPF can be exactly divided by 12; t is an integer by which 48 × n RPF can be exactly divided; and Lg. With the present invention, the number of the SRS resources in a LTE-A system can be efficiently increased.

Abstract: Imaging agents comprising an isolated polypeptide conjugated with a radionuclide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.

Abstract: A book spread identification arrangement for a board book is provided, the arrangement comprising a plurality of conductive paths, contact means disposed adjacent at least part of at least one of the conductive paths and processing means connected to the conductive paths and configured for processing signals associated with the conductive paths. One selection end of each path is disposed adjacent the spine surface of the book. The contact means comprise one or more conductive surfaces and are arranged, upon opening of the book to a spread, to contact one of a plurality of combinations of one or more of the conductive paths. Each of the plurality of combinations is in a predetermined unique association with a respective single spread of the book. From the processed signals, the processing means are able to determine the particular combination of conductive paths contacted by the contact means and identify to which spread the book is open.

Abstract: The present invention provides a method for transmitting reference signals comprising: during carrier aggregation, a user equipment sending physical uplink shared channel (PUSCH) on one or more component carriers, and sending demodulation reference signals (DM RS) for the PUSCH on each section of bandwidth occupied by the PUSCH on each component carrier, wherein a DM RS sequence on a section of bandwidth is an independent sequence or part of an independent sequence and forms an independent sequence with DM RS sequences on multiple sections of bandwidth other than the section of bandwidth; the section of bandwidth is a section of continuous bandwidth occupied by the PUSCH on any component carrier, or is any of the multiple sections of bandwidth occupied by the PUSCH on any component carrier. The Present invention further provides a corresponding apparatus.

Abstract: This disclosure describes techniques for estimating a depth of image objects for a two-dimensional (2D) view of a video presentation. For example, a plurality of feature points may be determined for a 2D view. The plurality of feature points may be used to estimate global motion, e.g., motion of an observer (e.g., camera), of the 2D view. For example, the plurality of feature points may be used to generate a global motion frame difference. The global motion frame difference may be used to create a depth map for the 2D view, which may be used to generate an alternative view of the video presentation that may be used to display a three-dimensional (3D) video presentation.

Abstract: This disclosure describes techniques for estimating a depth of image objects for a two-dimensional (2D) view of a video presentation. For example, an initial indication of depth (e.g., an optical flow) may be determined for a 2D view. The initial indication of depth may be used to estimate global motion, e.g., motion of an observer (e.g., camera), of the 2D view. The initial indication of depth may be modified based on the estimation of global motion to create a global motion-adjusted indication of depth. The global motion-adjusted depth indication may be used to create a depth map for the 2D view, which may be used to generate an alternative view of the video presentation that may be used to display a three-dimensional (3D) video presentation.

Abstract: An eNB, user equipment, system and method for transmitting sounding reference signals by using multiple antennas are disclosed in the present invention, which can reduce overhead of uplink sounding reference signals. The method includes: if an Advanced Long Term Evolution (LTE-A) system has uplink multiple antennas, an eNB configures respectively transmission periods of Sounding Reference Signals (SRSs) which are transmitted over each antenna for a User Equipment (UE); according to the configuration by the eNB, the UE transmits an uplink SRS over each antenna with the corresponding SRS transmission period. The present invention can reduce the uplink SRS overhead in the system remarkably if there are multiple antennas.

Abstract: One or more snapshots of data stored over a period of time are maintained in a hybrid storage device comprising a magnetic disk and a solid state disk, wherein a selected snapshot stores information that allows recovery of data that is stored in the hybrid storage device at a selected point in time of the period of time. The hybrid storage device receives an input/output (I/O) command from a computational device. A category of a plurality of categories to which the I/O command belongs is determined, wherein the plurality of categories comprise writing to an unused block, writing to a used block, reading from an unused block, and reading from a used block. In response to determining the category to which the I/O command belongs, the I/O command is handled by one of the magnetic disk and the solid state disk based on the determined category.

Abstract: Provided herein are PDGF-R? imaging agents that are polypeptides labeled with a signal generator (e.g., paramagnetic label, a radionuclide, or a fluorophore), wherein the imaging agents bind specifically to PDGFR-?. Also provided are in vivo imaging methods using the imaging agents.

Abstract: A portable communication device includes a receiving module, a pulse signal generating module, a timer module, and detection module. The receiving module is configured for receiving incoming signals sent to the portable communication device. The pulse signal generating module is configured for generating pulse signals when a portable communication device body is tapped. There is a first predetermined limit and a second predetermined limit, and the timer module is configured for starting timing when the pulse signal generating module generates the pulse signals, and stopping timing at the second predetermined limit. The detection module is configured for starting to detect if the pulse signal generating module generates pulse signals at the time between the first predetermined limit and the second predetermined limit. The detection module directs the receiving module to refuse or accept the incoming signals according to detecting results.

Abstract: A phenyl tin compound is synthesized by using a derivative having various functional groups and a bromo- or iodo-benzene ring as a labeling material of a radioactive ligand. On the other hand, a novel hydroxytosyl iodobenzene compound having an electron-donating group is obtained by oxidizing iodobenzene having one or more electron-donating groups and reacting it with tosylic acid. Then, a diphenyliodonium salt which is a labeling precursor is synthesized by reacting the resulting compound with various phenyl tin compounds. Finally, a 18F-labeled ligand having various functional groups and a [18F] fluorobenzene ring is synthesized by reacting the resulting diphenyliodonium salt with [18F]F?.

Abstract: A kind of growth method of Fe3N, and the growth is in the MOCVD system, including following process: 1). the surface nitridation of sapphire substrate would be made; 2). pump in carrier gas N2, ammonia and organic gallium sources, and grow low temperature GaN buffer on substrate; 3). the temperature would be raised and grow the GaN supporting layer; 4). pump in FeCp2 as Fe sources, then grow Fe3N on the GaN supporting layer; the Fe3N granular films and the Fe3N single crystal films could be obtained. The invention realizes growing high quality Fe3N film. According to the problem of growing material with difficulty, the problems are solved by controlling and adjusting the conditions for the flux of organic gallium source and iron source, growth temperature, growth time, the flux of ammonia, and mole ratio of N and Ga. In the invention, the method is easy, the growth process could be controlled, and thus the growth method and the process control of growth technology have advancement.

Abstract: In one aspect, the present invention provides a protected ligand precursor having structure XX wherein R8 is independently at each occurrence a protected hydroxy group, a protected C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, and b is 0-4; R9-R11 are independently at each occurrence hydrogen, a protected C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, with the proviso that at least one of R8-R11 is a protected hydroxy group or a protected C1-C3 hydroxyalkyl group; and R12 and R13 are independently at each occurrence a protecting group is selected from the group consisting of C1-C30 aliphatic radicals, C3-C30 cycloaliphatic radicals, and C2-C30 aromatic radicals.

Abstract: A method of diagnostic imaging is disclosed comprising administering a medical formulation to a subject, the formulation comprising a contrast enhancement agent having structure I and salts thereof wherein R1 is independently at each occurrence a hydroxy group, a C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, and b is 0-4; R2-R7 are independently at each occurrence hydrogen, a C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, with the proviso that at least one of R1-R7 is a hydroxy group or a C1-C3 hydroxyalkyl group; and wherein Q is one or more charge balancing counterions; and one or more pharmaceutically acceptable carriers and excipients. The subject is subjected to a diagnostic imaging technique such as magnetic resonance imaging. The technique may be used in a variety of diagnostic imaging regimes, such as imaging of circulatory systems, genitourinary systems, hepatobiliary systems, central nervous systems, tumors, and abscesses among others.

Abstract: In one aspect, the present invention provides a contrast enhancement agent comprising an iron chelate having structure I and salts thereof wherein R1 is independently at each occurrence a hydroxy group, a C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, and b is 0-4; R2-R7 are independently at each occurrence hydrogen, a C1-C3 hydroxyalkyl group, or a C1-C3 alkyl group, with the proviso that at least one of R1-R7 is a hydroxy group or a C1-C3 hydroxyalkyl group; and wherein Q is one or more charge balancing counterions. Also provided are a metal chelating ligand having structure IX and medical formulations comprising the contrast enhancement agent I.

Abstract: This invention presents a growth method for GaN based quantum wells red light LED structure by MOCVD epitaxy growth system, GaN based GaN/InGaN quantum wells red light LED structure material is obtained. The In mole fraction (x) for quantum well material InGaN is controlled between 0.1 and 0.5. This invention realizes the lumiscience of long wave length red light in group III nitrides. Aiming at the problem of difficulty in growing high In composition InGaN material, this invention solves this problem by controlling and adjusting the flux of organic Ga source and In source, growth temperature, time, and the flux of ammonia, and the mole ratio of N to Ga. By strictly controlling the conditions such as temperature and the flux ratio of reactant in the whole process, this invention determines the radiation wave length of quantum well, realizes the lumiscience of long wave length, and obtained GaN based GaN/InGaN quantum well red light LED structure.

Abstract: The present invention relates to a photosensitive detector with a composite dielectric gate MOSFET structure and its signal readout method. The MOSFET structure detector is formed on a p-type semiconductor substrate. N-type semiconductor regions locate on the two sides of the top part of the p-type semiconductor substrate to form a source and a drain. An underlying dielectric layer, a photo-electron storage layer, a top dielectric layer, and a control gate are stacked on the substrate in sequence. The top insulating dielectric layer can prevent the photoelectrons stored in the photo-electron storage layer from leaking into the control gate. The source and the drain are floating when photoelectrons are collected and injected into the photoelectron storing layer to be held therein. There is a transparent or semi-transparent window for detecting incident light forming on the substrate or gate surface.

Abstract: A special measuring bottle for measuring volume of solid includes a bottle body and a lid body. The bottle body is filled with a liquid and has an accommodating cavity to be accommodated with a sample solid and a reading cavity communicating with the accommodating cavity. The size of the inner edge of the accommodating cavity is larger than that of the reading cavity. Meanwhile, the accommodating cavity is formed an opening, and the reading cavity is arranged a plurality of graduations available for reading the level position of liquid. The lid body is sealed at the opening just like a shroud. Thereby, when the volume of a solid is measured by the displacing method, the accuracy of measurement by the special measuring bottle is higher than that by a common graduate of close volume, and by the special measuring bottle the specific weight of the sample solid can be less than that of the adapted liquid.