Patents by Inventor Rosanne M. Crooke

Rosanne M. Crooke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense modulation of c-reactive protein expression
    Publication number: 20040241844
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for treatment of diseases associated with expression of C-reactive protein are provided.
    Type: Application
    Filed: June 17, 2004
    Publication date: December 2, 2004
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of apolipoprotein(a) expression
    Publication number: 20040242516
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein(a). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein(a). Methods of using these compounds for modulation of apolipoprotein(a) expression and for treatment of diseases associated with expression of apolipoprotein(a) are provided.
    Type: Application
    Filed: May 21, 2004
    Publication date: December 2, 2004
    Inventors: Rosanne M Crooke, Mark J Graham
  • Modulation of apolipoprotein C-III expression
    Publication number: 20040208856
    Abstract: Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided.
    Type: Application
    Filed: April 16, 2003
    Publication date: October 21, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Rosanne M. Crooke, Mark J. Graham, Kristina M. Lemonidis, Kenneth W. Dobie
  • Antisense modulation of short heterodimer partner-1 expression
    Publication number: 20040192633
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of short heterodimer partner-1. The compositions contain antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding short heterodimer partner-1. Methods of using these compounds for modulation of short heterodimer partner-1 expression and for treatment of diseases associated with expression of short heterodimer partner-1 are provided.
    Type: Application
    Filed: April 29, 2004
    Publication date: September 30, 2004
    Applicant: ISIS Pharmaceuticals, Inc.
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of microsomal triglyceride transfer protein expression
    Patent number: 6767739
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of microsomal triglyceride transfer protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding microsomal triglyceride transfer protein.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: July 27, 2004
    Assignee: ISIS Pharmaceuticals Inc.
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Modulation of apolipoprotein (a) expression
    Publication number: 20040138164
    Abstract: Compounds, compositions and methods are provided for modulating the expression of apolipoprotein(a). The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein(a). Methods of using these compounds for modulation of apolipoprotein(a) expression and for diagnosis and treatment of disease associated with expression of apolipoprotein(a) are provided.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 15, 2004
    Applicant: ISIS Pharmaceuticals, Inc.
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of apolipoprotein B expression
    Publication number: 20030215943
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein B. Methods of using these compounds for modulation of apolipoprotein B expression and for treatment of diseases associated with expression of apolipoprotein B are provided.
    Type: Application
    Filed: May 15, 2002
    Publication date: November 20, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of apolipoprotein (A) expression
    Publication number: 20030119766
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein(a). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein(a). Methods of using these compounds for modulation of apolipoprotein(a) expression and for treatment of diseases associated with expression of apolipoprotein(a) are provided.
    Type: Application
    Filed: August 7, 2001
    Publication date: June 26, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of acyl coenzyme a cholesterol acyltransferase-1 expression
    Publication number: 20030096773
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of acyl coenzyme A cholesterol acyltransferase-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding acyl coenzyme A cholesterol acyltransferase-1. Methods of using these compounds for modulation of acyl coenzyme A cholesterol acyltransferase-1 expression and for treatment of diseases associated with expression of acyl coenzyme A cholesterol acyltransferase-1 are provided.
    Type: Application
    Filed: August 1, 2001
    Publication date: May 22, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham, Kristina M. Lemonidis
  • Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
    Publication number: 20030096772
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of acyl CoA cholesterol acyltransferase-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding acyl CoA cholesterol acyltransferase-2. Methods of using these compounds for modulation of acyl CoA cholesterol acyltransferase-2 expression and for treatment of diseases associated with expression of acyl CoA cholesterol acyltransferase-2 are provided.
    Type: Application
    Filed: July 30, 2001
    Publication date: May 22, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham, Kristina M. Lemonidis
  • Antisense modulation of cholesteryl ester transfer protein expression
    Publication number: 20030092647
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of cholesteryl ester transfer protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding cholesteryl ester transfer protein. Methods of using these compounds for modulation of cholesteryl ester transfer protein expression and for treatment of diseases associated with expression of cholesteryl ester transfer protein are provided.
    Type: Application
    Filed: August 8, 2001
    Publication date: May 15, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham, Pamela Nero, Edward Wancewicz
  • Antisense modulation of apolipoprotein B expression
    Publication number: 20030087853
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein B. Methods of using these compounds for modulation of apolipoprotein B expression and for treatment of diseases associated with expression of apolipoprotein B are provided.
    Type: Application
    Filed: August 1, 2001
    Publication date: May 8, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of microsomal triglyceride transfer protein expression
    Publication number: 20030086912
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of microsomal triglyceride transfer protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding microsomal triglyceride transfer protein. Methods of using these compounds for modulation of microsomal triglyceride transfer protein expression and for treatment of diseases associated with expression of microsomal triglyceride transfer protein are provided.
    Type: Application
    Filed: July 30, 2001
    Publication date: May 8, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of short heterodimer partner-1 expression
    Publication number: 20030083484
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of short heterodimer partner-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding short heterodimer partner-1. Methods of using these compounds for modulation of short heterodimer partner-1 expression and for treatment of diseases associated with expression of short heterodimer partner-1 are provided.
    Type: Application
    Filed: July 31, 2001
    Publication date: May 1, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of stearoyl-CoA desaturase expression
    Publication number: 20030083282
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
    Type: Application
    Filed: July 30, 2001
    Publication date: May 1, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham
  • Antisense modulation of C-reactive protein expression
    Publication number: 20030083280
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for treatment of diseases associated with expression of C-reactive protein are provided.
    Type: Application
    Filed: July 25, 2001
    Publication date: May 1, 2003
    Inventors: Rosanne M. Crooke, Mark J. Graham