Patents by Inventor Rotem Sorek

Rotem Sorek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7906635
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: March 15, 2011
    Assignee: Compugen Ltd.
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Patent number: 7842459
    Abstract: Novel splice variant nucleic acid sequences. The novel splice variants and their nucleic acid sequences according to the present invention may optionally be used for diagnosis of a variant-detectable disease as described herein.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: November 30, 2010
    Assignee: Compugen Ltd.
    Inventors: Michal Ayalon-Soffer, Sarah Pollock, Ronen Shemesh, Rotem Sorek, Zurit Levine, Zipi Shaqed, Amir Toporik, Gad S. Cojocaru, Dvir Dahary, Guy Kol, Pinchas Akiva, Amit Novik, Sergey Nemzer, Alexander Diber, Maxim Shklar, Osnat Sella-Tavor, Lily Bazak, Ariel Farkash, Yossi Cohen
  • Publication number: 20100124786
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Application
    Filed: January 15, 2009
    Publication date: May 20, 2010
    Applicant: Compugen LTD
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Publication number: 20100120022
    Abstract: Novel splice variant nucleic acid sequences. The novel splice variants and their nucleic acid sequences according to the present invention may optionally be used for diagnosis of a variant-detectable disease as described herein.
    Type: Application
    Filed: January 27, 2005
    Publication date: May 13, 2010
    Inventors: Michal Ayalon-Soffer, Sarah Pollock, Ronen Shemesh, Rotem Sorek, Zurit Levine, Zipi Shaqed, Amir Toporik, Gad S. Cojocaru, Dvir Dahary, Guy Kol, Pinchas Akiva, Amit Novik, Sergey Nemzer, Alexander Diber, Maxim Shklar, Osnat Sella-Tavor, Lily Bazak, Ariel Farkash, Yossi Cohen
  • Publication number: 20100068736
    Abstract: Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 18, 2010
    Applicant: Compugen LTD.
    Inventors: Sarah Pollock, Zurit Levine, Amit Novik, Dvir Dahary, Rotem Sorek, Amir Toporik, Shirley Sameah-Greenwald, Osnat Sella-Tavor, Alexander Diber, Gad S. Cojocaru, Michal Ayalon-Soffer, Shira Walach, Pinchas Akiva, Naomi Keren, Ronen Shemesh
  • Publication number: 20100050303
    Abstract: We describe a method for mining microbial genomes to discover antimicrobial genes and proteins having broad spectrum of activity. Also described are antimicrobial genes and their expression products from various microbial genomes that were found using this method. The products of such genes can be used as antimicrobial agents or as tools for molecular biology.
    Type: Application
    Filed: December 15, 2007
    Publication date: February 25, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Rotem Sorek, Edward M. Rubin
  • Patent number: 7667001
    Abstract: Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: February 23, 2010
    Assignee: Compugen Ltd.
    Inventors: Sarah Pollock, Zurit Levine, Amit Novik, Dvir Dahary, Rotem Sorek, Amir Toporik, Shirley Sameah-Greenwald, Osnat Sella-Tavor, Alexander Diber, Gad S. Cojocaru, Michal Avalon-Soffer, Shira Walach, Pinchas Akiva, Naomi Keren, Ronen Shemesh
  • Publication number: 20090286957
    Abstract: Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
    Type: Application
    Filed: January 8, 2009
    Publication date: November 19, 2009
    Applicant: Compugen LTD
    Inventors: Amir Toporik, Dvir Dahary, Rotem Sorek, Sarah Pollock, Zurit Levine, Pinchas Akiva, Alexander Diber, Amit Novik, Osnat Sella-Tavor, Michal Ayalon-Soffer, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Naomi Keren, Maxim Shklar
  • Publication number: 20090215046
    Abstract: Novel markers for colon cancer that are both sensitive and accurate. These markers are overexpressed in colon cancer specifically, as opposed to normal colon tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of colon cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between colon cancer and non-cancerous states.
    Type: Application
    Filed: October 23, 2007
    Publication date: August 27, 2009
    Applicant: COMPUGEN LTD.
    Inventors: Rotem Sorek, Michal Ayalon-Soffer, Dvir Dahary, Amit Novik, Amir Toporik, Alexander Diber, Guy Kol, Sarah Pollock, Zurit Levine, Gad S. Cojocaru, Ronen Shemesh, Yossi Cohen, Osnat Sella-Tavor, Shirley Sameah-Greenwald, Shira Walach
  • Patent number: 7569662
    Abstract: Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: August 4, 2009
    Assignee: Compugen Ltd
    Inventors: Sarah Pollock, Zurit Levine, Amit Novik, Dvir Dahary, Rotem Sorek, Amir Toporik, Shirley Sameah-Greenwald, Osnat Sella-Tavor, Alexander Diber, Gad S. Cojocaru, Michal Ayalon-Soffer, Shira Walach, Pinchas Akiva, Naomi Keren, Ronen Shemesh
  • Patent number: 7553948
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: June 30, 2009
    Assignee: Compugen Ltd
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Patent number: 7528243
    Abstract: Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: May 5, 2009
    Assignee: Compugen Ltd
    Inventors: Amir Toporik, Dvir Dahary, Rotem Sorek, Sarah Pollock, Zurit Levine, Pinchas Akiva, Alexander Diber, Amit Novik, Osnat Sella-Tavor, Michal Ayalon-Soffer, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Naomi Keren, Maxim Shklar
  • Publication number: 20090004648
    Abstract: Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
    Type: Application
    Filed: March 6, 2007
    Publication date: January 1, 2009
    Applicant: COMPUGEN LTD.
    Inventors: Gad S. Cojocaru, Sarah Pollock, Zurit Levine, Alexander Diber, Guy Kol, Amir Toporik, Rotem Sorek, Dvir Dahary, Michal Ayalon-Soffer, Pinchas Akiva, Amit Novik, Yossi Cohen, Osnat Sella-Tavor, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Maxim Shklar
  • Patent number: 7368548
    Abstract: Novel markers for prostate cancer that are both sensitive and accurate. Furthermore, these markers are able to distinguish between prostate cancer and benign prostate hyperplasia (“BPH”). These markers are overexpressed in prostate cancer specifically, as opposed to normal prostate tissue and/or BPH. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of prostate cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between prostate cancer and non-cancerous states.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: May 6, 2008
    Assignee: Compugen Ltd.
    Inventors: Dvir Dahary, Sarah Pollock, Zurit Levine, Rotem Sorek, Michal Ayalon-Soffer, Pinchas Akiva, Amir Toporik, Osnat Sella-Tavor, Shirley Sameah-Greenwald
  • Publication number: 20070259386
    Abstract: Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
    Type: Application
    Filed: February 28, 2007
    Publication date: November 8, 2007
    Applicant: COMPUGEN LTD.
    Inventors: Amir Toporik, Dvir Dahary, Rotem Sorek, Sarah Pollock, Zurit Levine, Pinchas Akiva, Alexander Diber, Amit Novik, Osnat Sella-Tayor, Michal Ayalon-Soffer, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Naomi Keren, Maxim Shklar
  • Publication number: 20070082337
    Abstract: A method of identifying alternatively spliced exons is provided. The method comprising, scoring each of a plurality of exon sequences derived from genes of a species according to at least one sequence parameter, wherein exon sequences of the plurality of exon sequences scoring above a predetermined threshold represent alternatively spliced exons, thereby identifying the alternatively spliced exons.
    Type: Application
    Filed: January 27, 2005
    Publication date: April 12, 2007
    Applicant: Compugen Ltd.
    Inventors: Rotem Sorek, Sarah Pollock, Alex Diber, Zurit Levine, Sergey Nemzer, Guy Kol, Assaf Wool, Ami Haviv, Yuval Cohen, Yossi Cohen, Ronen Shemesh, Kinneret Savitsky
  • Publication number: 20060263786
    Abstract: Novel markers for colon cancer that are both sensitive and accurate. These markers are overexpressed in colon cancer specifically, as opposed to normal colon tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of colon cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between colon cancer and non-cancerous states.
    Type: Application
    Filed: January 27, 2005
    Publication date: November 23, 2006
    Inventors: Rotem Sorek, Michal Ayalon-Soffer, Dvir Dahary, Amit Novik, Amir Toporik, Alexander Diber, Guy Kol, Sarah Pollock, Zurit Levine, Gad Coiocaru, Ronen Shemesh, Yossi Cohen, Osnat Sella-Tavor, Shirley Sameah-Greenwald, Shira Walach
  • Publication number: 20060183131
    Abstract: Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 17, 2006
    Inventors: Amir Toporik, Dvir Dahary, Rotem Sorek, Sarah Pollock, Zurit Levine, Pinchas Akiva, Alexander Diber, Amit Novik, Osnat Sella-Tavor, Michal Ayalon-Soffer, Shira Walach, Shirley Sameah-Greenwald, Ronen Shemesh, Naomi Keren, Maxim Shklar
  • Publication number: 20060147946
    Abstract: Novel alpha 1 subunit splice variants, including nucleic and amino acid sequences. Methods of use thereof are also described.
    Type: Application
    Filed: January 27, 2005
    Publication date: July 6, 2006
    Inventors: Pinchas Akiva, Alexander Dlber, Sarah Pollock, Zurit Levine, Sergey Nemzer, Vladimir Grebinskiy, Brian Meloon, Andrew Olson, Avi Rosenberg, Ami Haviv, Shaul Zevin, Tomer Zekhari, Zipi Shaged, Moshe Olshansky, Arial Farkash, Eyal Privman, Amit Novik, Naomi Keren, Gad Cojocaru, Yossi Cohen, Ronen Shemesh, Osnat Sella-Tavor, Liat Mintz, Hanquing Xie, Dvir Dahary, Erez Levanon, Shiri Freilich, Nili Beck, Wei-Yong Zhu, Alon Wasserman, Chen Chermesh, Idit Azar, Rotem Sorek, Jeanne Bernstein
  • Publication number: 20060068405
    Abstract: Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.
    Type: Application
    Filed: January 27, 2005
    Publication date: March 30, 2006
    Inventors: Alex Diber, Sarah Pollock, Zurit Levine, Sergey Nemzer, Vladimir Grebinskiy, Brian Meloon, Andrew Olson, Avi Rosenberg, Ami Haviv, Shaul Zevin, Tomer Zekharia, Zipi Shaked, Moshe Olshansky, Ariel Farkash, Eyal Privman, Amit Novik, Naomi Keren, Gad Cojocaru, Pinchas Akiva, Yossi Cohen, Ronen Shemesh, Osnat Sella-Tavor, Liat Mintz, Hanqing Xie, Dvir Dahary, Erez Levanon, Shiri Freilich, Nili Beck, Wei-Yong Zhu, Alon Wasserman, Chen Chermesh, Idit Azar, Rotem Sorek, Jeanne Bernstein