Abstract: The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.

Abstract: The present invention relates to a method for isolating proteins from a solution containing the proteins. The invention also relates to a method for the chromatographic separation of proteins. The present invention also relates to crosslinked hydroxylic polymer particles functionalized with temperature-responsive copolymer, and to methods of preparing such particles.

Abstract: Fetal heart rate monitoring using ultrasound by means of a transducer in contact with the maternal abdomen. The transducer (11) is driven by a transmit amplifier (12), a receive amplifier (13) amplifies the echoes detected by the transducer. While the receive gate is open, demodulator (14) multiplies the received signal by the local oscillator signal. The sum of the frequencies is removed by low-pass filter (15), while the difference of the frequencies is the Doppler frequency of the received signal which passes through the filter to be digitised by ADC (16), the Rx gate opening a fixed delay after the end of the transmit pulse. A number of range bins are chosen and two ADC readings are made for each bin in intervals during the Rx gate-open interval. One or two of the Doppler audio signals, aperiodic or periodic, will contain the signal from the fetal heart. When a periodic signal is found, its rate is tested to see if it lies within or outside the typical range of a fetal heart.

Abstract: A connector comprises an adapter housing coupled to a connector housing. An adapter insert has a first cavity formed therein. The first cavity is shaped to at least partially restrain motion in a first lateral axis of a flat cable placed therein. An apparatus for connecting a flat cable to an electrical connector comprises an adapter housing. An adapter insert has a first cavity shaped to at least partially restrain motion in a first lateral axis of a flat cable placed therein. An elastomer spring element is disposed in a second cavity in the adapter insert. The elastomer spring element imparts a squeeze on the flat cable at least partially restraining motion of the flat cable in a second lateral axis substantially orthogonal to the first lateral axis.

Abstract: The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.

Abstract: A connector comprises a housing having a seal element located within the housing. The seal element has an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage. A seal for an electrical connector comprises an elastomer seal element having an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage.

Abstract: The invention provides a method of preparing a crosslinked polymer, which method comprises polymerising branched polyunsaturated monomers by a metathesis polymerisation reaction, wherein the branched polyunsaturated monomers contain acyclic ethylenically unsaturated groups that are capable of undergoing polymerization by a metathesis reaction such that the metathesis polymerisation produces a crosslinked polymer and substantially no non-volatile ethylenically unsaturated by-products.

Abstract: An apparatus for providing electrical power through a downhole packer comprises a riser nipple engagingly insertable in a passage in the packer; a sleeve surrounding a portion of the riser nipple and slidingly moveable between a cable assembly position and an operational position enabling connection of a cable extending through the packer and the sleeve to an electrical connector; and a retaining nut engageable with the riser nipple capturing the sleeve in the operational position when the retaining nut is engaged with the riser nipple.

Abstract: A connector comprises a housing having a seal element located within the housing. The seal element has an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage. A seal for an electrical connector comprises an elastomer seal element having an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage.

Abstract: An apparatus for engaging an electrical conductor comprises a gripping contact having a plurality of fingers, where the plurality of fingers has a substantially conical outer surface. A contact receptacle has a substantially conical inner surface. A tension member urges the gripping contact toward the contact receptacle such that interaction between the substantially conical outer surface and the substantially conical inner surface forces the plurality of fingers to engagingly compress the electrical conductor placed between the fingers. A method of engaging an electrical conductor comprises inserting an electrical conductor between a plurality of fingers of a gripping contact, where the plurality of fingers has a substantially conical outer surface. The substantially conical outer surface of the gripping contact is urged to interact with a substantially conical inner surface of a contact receptacle such that the interaction forces the plurality of fingers to engage the electrical conductor.

Abstract: A connector comprises a substantially cylindrical housing having an internal circumferential groove therein. A seal element is disposed within the housing, the seal element having an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage. A follower abuts the seal element. A spring is disposed in the groove acting against the follower and forcing the follower against the seal to maintain a fluid seal on the cable element.

Abstract: A connector comprises an adapter housing coupled to a connector housing. An adapter insert has a first cavity formed therein. The first cavity is shaped to at least partially restrain motion in a first lateral axis of a flat cable placed therein. An apparatus for connecting a flat cable to an electrical connector comprises an adapter housing. An adapter insert has a first cavity shaped to at least partially restrain motion in a first lateral axis of a flat cable placed therein. An elastomer spring element is disposed in a second cavity in the adapter insert. The elastomer spring element imparts a squeeze on the flat cable at least partially restraining motion of the flat cable in a second lateral axis substantially orthogonal to the first lateral axis.

Abstract: A connector comprises a substantially cylindrical housing having an internal circumferential groove therein. A seal element is disposed within the housing, the seal element having an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage. A follower abuts the seal element. A spring is disposed in the groove acting against the follower and forcing the follower against the seal to maintain a fluid seal on the cable element.

Abstract: A connector comprises a first housing having a shoulder on an end thereof. A second housing has a first thread on an end thereof. A coupling nut engages the shoulder and has a second thread on an end thereof, where the second thread is engageable with the first thread. Engagement of the first thread and the second thread brings the first housing and the second housing into an operative position with no more than two revolutions of the coupling nut. A method of assembling a connector comprises providing a first housing having a shoulder on an end thereof. A coupling nut engages the shoulder. A first thread on the coupling nut engages a second thread on a second housing, and rotating the coupling nut no more than two revolutions brings the first housing and the second housing into an operative position.

Abstract: An apparatus for engaging an electrical conductor comprises a gripping contact having a plurality of fingers, where the plurality of fingers has a substantially conical outer surface. A contact receptacle has a substantially conical inner surface. A tension member urges the gripping contact toward the contact receptacle such that interaction between the substantially conical outer surface and the substantially conical inner surface forces the plurality of fingers to engagingly compress the electrical conductor placed between the fingers. A method of engaging an electrical conductor comprises inserting an electrical conductor between a plurality of fingers of a gripping contact, lo where the plurality of fingers has a substantially conical outer surface. The substantially conical outer surface of the gripping contact is urged to interact with a substantially conical inner surface of a contact receptacle such that the interaction forces the plurality of fingers to engage the electrical conductor.

Abstract: A connector comprises a housing having a seal element located within the housing. The seal element has an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage. A seal for an electrical connector comprises an elastomer seal element having an axial passage therethrough. A plurality of circumferential sealing lips are spaced apart along the axial passage and sized such that each of the plurality of circumferential sealing lips provides a compression seal along a cable element inserted through the axial passage.

Abstract: The present disclosure concerns compounds of formula (I) and pharmaceutically acceptable salts, hydrates, solvates, pharmaceutically acceptable derivatives, pro-drugs, tautomers and/or isomers thereof.

Abstract: This invention relates to compounds to formula (1) wherein B is optionally substituted aryl; R1 and R2 are the same or different and are independently selected from hydrogen or C1-3 alkyl; n is 1 or 2, preferably n is 1; m is 0 or 1; R3 is hydrogen or acyl, R4 and R5 are the same or different and are independently selected from amino, alkylamino, dialkylamino, arylamino and C2-C4 cycloalkylamino; X and Y are independently selected from C, H or N provided at least one of X and Y is N; and salts thereof, solvates thereof, pharmaceutically acceptable derivatives thereof, prodrugs thereof, tautomers thereof and/or isomers thereof, and processes for their reparation and methods of treatment, pharmaceutical formulations and uses involving them.

Abstract: The present disclosure concerns compounds of formula (I) and pharmaceutically acceptable salts, hydrates, solvates, pharmaceutically acceptable derivatives, pro-drugs, tautomers and/or isomers thereof. The disclosure also relates to processes for the preparation of compounds according to formula (I), pharmaceutical or veterinary compositions containing such compounds or methods of treatment and/or prophylaxis of a condition or symptom that is inhibited, reduced or alleviated by opioid receptor activation.

Abstract: An apparatus and method for reclaiming uncured concrete are disclosed. The apparatus includes a hopper with water inlet for introducing water to the hopper. The outlet of the hopper is connected to a separator that is suitably connected to the hopper to receive material therefrom. A screen is positioned in the separator to separate material flowing therethrough. The separator has two outlets for removing material from the separator.