Patents by Inventor Roy K. Greenberg
Roy K. Greenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10251743Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. Indwelling access sheaths are provided within auxiliary lumens of a pusher catheter and dilators are preloaded into the access sheaths along with the indwelling guide wire. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertisation of a side branch or target vessel through the fenestration or be used to stabilise the access sheath during catheterisation, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.Type: GrantFiled: November 7, 2016Date of Patent: April 9, 2019Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik E. Rasmussen
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Patent number: 10201414Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (21) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: GrantFiled: September 20, 2017Date of Patent: February 12, 2019Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Publication number: 20190000607Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. The indwelling guide wire are configured to receive the access sheaths. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.Type: ApplicationFiled: August 21, 2018Publication date: January 3, 2019Applicants: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik E. Rasmussen
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Patent number: 10143576Abstract: A stent graft has a tubular body with a first bifurcation with first and second legs extending from the bifurcation. One of the legs has a further bifurcation to define a side arm. The stent graft can be deployed into the vasculature of a patient with the tubular body being in an aorta of the patient, a first leg extending down an iliac artery, a second leg being directed towards a contralateral iliac artery and the side arm directed to an internal artery of one of the iliac arteries. One of the legs can include a valved aperture to enable the placement of an indwelling catheter therethrough.Type: GrantFiled: July 17, 2017Date of Patent: December 4, 2018Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, David E. Hartley, Michael Lawrence-Brown
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Patent number: 10092391Abstract: The present embodiments provide an endoluminal prosthesis having modular branches, and systems and methods for facilitating deployment of the endoluminal prosthesis. In one example, the endoluminal prosthesis comprises a graft including a bifurcated body of a biocompatible material. The bifurcated body includes distally extending limbs. Limb extensions can be longitudinally and circumferentially adjusted prior to mating with the limbs to enable an “off-the-shelf” prosthesis that can conform to various complex anatomy. When adjusted and mated, fenestrations in the limb extensions can align with branch vessels.Type: GrantFiled: December 23, 2013Date of Patent: October 9, 2018Assignees: The Cleveland Clinic Foundation, Cook Medical Technologies LLCInventors: Roy K. Greenberg, Blayne A. Roeder
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Publication number: 20180243076Abstract: An endoluminal prosthesis comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch having a first branch lumen and a branch wall, and a second prosthetic branch having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.Type: ApplicationFiled: April 13, 2018Publication date: August 30, 2018Applicant: The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Karl J. West, Davorin K. Skender, James C. Foster
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Publication number: 20180174303Abstract: A computer implemented method for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure. A gradient field of a distance transformation is computed for the edge-detected dataset. A voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field.Type: ApplicationFiled: January 30, 2018Publication date: June 21, 2018Inventors: Vikash R. Goel, Donald P. Greenberg, Roy K. Greenberg
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Publication number: 20180153680Abstract: A branched and fenestrated prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. The branched and fenestrated prosthesis may include a plurality of branches and a plurality of fenestrations.Type: ApplicationFiled: February 5, 2018Publication date: June 7, 2018Applicants: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Karl J. West, Timothy A. Resch, Blayne A. Roeder
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Patent number: 9943400Abstract: An endoluminal prosthesis comprises a prosthetic trunk having a trunk lumen and a trunk wall, a first prosthetic branch having a first branch lumen and a branch wall, and a second prosthetic branch having a second branch lumen. The first branch lumen and the second branch lumen are both in fluid communication with the trunk lumen through the trunk wall and the second branch lumen is in fluid communication with the first branch lumen through the branch wall. Additional devices, systems, and methods are disclosed.Type: GrantFiled: September 4, 2015Date of Patent: April 17, 2018Assignee: The Cleveland Clinic FoundationInventors: Roy K. Greenberg, Karl J. West, Davorin K. Skender, James C. Foster
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Patent number: 9922424Abstract: A computer implemented method for determining a centerline of a three-dimensional tubular structure is described. The method includes providing an edge-detected data set of voxels that characterize a boundary of the tubular structure according to a three-dimensional voxel data set for the tubular structure. A gradient field of a distance transformation is computed for the edge-detected dataset. A voxel data set corresponding to a centerline of the tubular structure is computed according to derivative of gradient field.Type: GrantFiled: June 1, 2015Date of Patent: March 20, 2018Assignee: The Cleveland Clinic FoundationInventors: Vikash R. Goel, Donald P. Greenberg, Roy K. Greenberg
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Patent number: 9883938Abstract: A system for facilitating deployment of an endoluminal prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. A wire segment may include a proximal portion positioned proximal of the proximal end opening and a distal portion positioned distal of the distal end opening. The wire segment extend through the fenestration and through the lumen of the branch in a preloaded configuration.Type: GrantFiled: October 2, 2015Date of Patent: February 6, 2018Assignees: COOK MEDICAL TECHNOLOGIES LLC, THE CLEVELAND CLINIC FOUNDATIONInventors: Roy K. Greenberg, Karl J. West, Timothy A. Resch, Blayne A. Roeder
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Publication number: 20170325978Abstract: A stent graft has a tubular body with a first bifurcation with first and second legs extending from the bifurcation. One of the legs has a further bifurcation to define a side arm. The stent graft can be deployed into the vasculature of a patient with the tubular body being in an aorta of the patient, a first leg extending down an iliac artery, a second leg being directed towards a contralateral iliac artery and the side arm directed to an internal artery of one of the iliac arteries. One of the legs can include a valved aperture to enable the placement of an indwelling catheter therethrough.Type: ApplicationFiled: July 17, 2017Publication date: November 16, 2017Applicants: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, David E. Hartley, Michael Lawrence-Brown
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Patent number: 9808365Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: GrantFiled: August 26, 2014Date of Patent: November 7, 2017Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Patent number: 9788982Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: GrantFiled: August 26, 2014Date of Patent: October 17, 2017Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Patent number: 9782284Abstract: An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.Type: GrantFiled: August 26, 2014Date of Patent: October 10, 2017Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: David Ernest Hartley, John Lennon Anderson, Roy K. Greenberg, Wolf Stelter
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Publication number: 20170252145Abstract: An endoluminal prosthesis may include a tubular main graft body including a sidewall and proximal and distal ends. A first stent may be positioned near the proximal end of the main graft body. A second stent may be positioned adjacent to and distal of the first stent. An opening in the sidewall may be positioned longitudinally between a peak of the first stent and a valley of the second stent. A tubular branch may be disposed in the opening. The branch may include first and second end openings. The branch may be flexibly orientable between a retrograde configuration in which the first end opening is oriented toward the distal end and the second end opening is oriented toward the proximal end and an antegrade configuration in which the first end opening is oriented toward the proximal end and the second end opening is oriented toward the distal end.Type: ApplicationFiled: May 24, 2017Publication date: September 7, 2017Applicants: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Blayne A. Roeder, Roy K. Greenberg, Jarin Kratzberg, Matthew S. Huser
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Publication number: 20170216013Abstract: A stent graft (2) for placement in the thoracic arch of a patient has a first tubular body portion (6) with a first lumen therein for placement in the ascending aorta of a patient and a second tubular body portion (8) to extend along the thoracic arch and down the descending aorta. The second tubular body portion is of a lesser diameter than the first tubular body portion. There is a step portion (10) between the first body portion and the second body portion. The step portion is joined to and continuous with the first portion and the second portion. A first side of each of the first body portion, the step portion and the second body portion are substantially aligned so that there is a step (18) defined on a second side opposite to the first side of the body portion. There is an aperture (30) in the step portion and an internal tube (32) extending from the aperture towards the first body portion.Type: ApplicationFiled: April 14, 2017Publication date: August 3, 2017Applicants: COOK MEDICAL TECHNOLOGIES LLC, THE CLEVELAND CLINIC FOUNDATIONInventors: David E. Hartley, Roy K. Greenberg, Krasnodar Ivancev, Michael Lawrence-Brown
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Patent number: 9707113Abstract: A stent graft has a tubular body with a first bifurcation with first and second legs extending from the bifurcation. One of the legs has a further bifurcation to define a side arm. The stent graft can be deployed into the vasculature of a patient with the tubular body being in an aorta of the patient, a first leg extending down an iliac artery, a second leg being directed towards a contralateral iliac artery and the side arm directed to an internal artery of one of the iliac arteries. One of the legs can include a valved aperture to enable the placement of an indwelling catheter therethrough.Type: GrantFiled: April 19, 2007Date of Patent: July 18, 2017Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Roy K. Greenberg, David Ernest Hartley, Michael Lawrence-Brown
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Patent number: 9662196Abstract: An endoluminal prosthesis may include a tubular main graft body including a sidewall and proximal and distal ends. A first stent may be positioned near the proximal end of the main graft body. A second stent may be positioned adjacent to and distal of the first stent. An opening in the sidewall may be positioned longitudinally between a peak of the first stent and a valley of the second stent. A tubular branch may be disposed in the opening. The branch may include first and second end openings. The branch may be flexibly orientable between a retrograde configuration in which the first end opening is oriented toward the distal end and the second end opening is oriented toward the proximal end and an antegrade configuration in which the first end opening is oriented toward the proximal end and the second end opening is oriented toward the distal end.Type: GrantFiled: September 25, 2012Date of Patent: May 30, 2017Assignees: Cook Medical Technologies LLC, The Cleveland Clinic FoundationInventors: Blayne A Roeder, Roy K Greenberg, Jarin Kratzberg, Matthew S Huser
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Patent number: 9655711Abstract: A stent graft (2) for placement in the thoracic arch of a patient has a first tubular body portion (6) with a first lumen therein for placement in the ascending aorta of a patient and a second tubular body portion (8) to extend along the thoracic arch and down the descending aorta. The second tubular body portion is of a lesser diameter than the first tubular body portion. There is a step portion (10) between the first body portion and the second body portion. The step portion is joined to and continuous with the first portion and the second portion. A first side of each of the first body portion, the step portion and the second body portion are substantially aligned so that there is a step (18) defined on a second side opposite to the first side of the body portion. There is an aperture (30) in the step portion and an internal tube (32) extending from the aperture towards the first body portion.Type: GrantFiled: July 7, 2015Date of Patent: May 23, 2017Assignees: COOK MEDICAL TECHNOLOGIES LLC, THE CLEVELAND CLINIC FOUNDATIONInventors: David E Hartley, Roy K Greenberg, Krasnodar Ivancev, Michael Lawrence-Brown