Abstract: An atomizer includes: a housing, defining an airflow passage extending through an inlet end and an outlet end; a liquid storage chamber, defined in the housing; an atomizing assembly, disposed in a path of the airflow passage and in fluid connection with the liquid storage chamber; a sealing element, including a sealing body and an air compensating valve, the sealing body is configured to form a seal between the housing and the atomizing assembly, the air compensating valve includes a first side located within the liquid storage chamber and a second side communicating with external air which are opposite to each other. The air compensating valve has a closed state configured to prevent aerosol generating material inside the liquid storage chamber from leaking and an opened state configured to allow the external air to enter the liquid storage chamber. The air compensating valve and the sealing body are integrally formed.

Abstract: An atomizer includes: a housing, defining a first airflow passage through an inlet end and an outlet end; a liquid storage chamber, disposed within the housing; an atomizing assembly, disposed in a path of the first airflow passage, the atomizing assembly is in fluid connection with the liquid storage chamber; a sealing element, including a sealing body and an air compensating valve, the sealing body is configured to form a seal between the housing and the atomizing assembly, the air compensating valve includes a first side and a second side opposite to each other, the first side is located within the liquid storage chamber, the second side communicates with external air. The air compensating valve is opened when a pressure of the external air on the second side is greater than a pressure in the liquid storage chamber on the first side.

Abstract: The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.

Abstract: Provided is a light source device, including: a light-emitting chip arranged on a base plate and configured to emit first light; a light guide rod including first and second light guide portions, the first light guide portion including a light incident end surface, the first light entering the light guide rod through the light incident end surface and being transmitted to the second light guide portion after passing through the first light guide portion, and the second light guide portion including a light-outputting surface for outputting light; a first positioning member including a first groove for accommodating the light guide rod, being directly or indirectly fixed relative to the base plate; and a movable fixing assembly configured to fix, together with the groove of the first positioning member, the light guide rod along a radial direction of the light guide rod, and deforms when fixing the light guide rod.

Abstract: A battery management system and a battery management method are provided. The battery management system includes a temperature sampling circuit, a plurality of voltage measurement circuits, a current sampling circuit, and a microcontroller. The temperature sampling circuit is configured to obtain a temperature parameter of a plurality of battery packs. The voltage measurement circuits are configured to obtain a plurality of open circuit voltage parameters of the battery packs. The current sampling circuit is configured to obtain a current parameter of the battery packs. The microcontroller obtains a plurality of initial state-of-charge parameters of the battery packs according to the open circuit voltage parameters and the temperature parameter and respectively calculates a plurality of present battery powers of the battery packs according to the initial state-of-charge parameters, the temperature parameter, and the current parameter.

Abstract: A battery management system and a battery management method are provided. The battery management system includes a temperature sampling circuit, a plurality of voltage measurement circuits, a current sampling circuit, and a microcontroller. The temperature sampling circuit is configured to obtain a temperature parameter of a plurality of battery packs. The voltage measurement circuits are configured to obtain a plurality of open circuit voltage parameters of the battery packs. The current sampling circuit is configured to obtain a current parameter of the battery packs. The microcontroller obtains a plurality of initial state-of-charge parameters of the battery packs according to the open circuit voltage parameters and the temperature parameter and respectively calculates a plurality of present battery powers of the battery packs according to the initial state-of-charge parameters, the temperature parameter, and the current parameter.

Abstract: An electronic vaporization assembly includes: a vaporization core having a heating element and a vaporization core body, the vaporization core body having a porous structure; a vaporization base having a vaporization top base, a vaporization bottom base, and a microgroove structure, the vaporization top base and the vaporization bottom base forming a vaporization cavity, the vaporization core being fixed between the vaporization top base and the vaporization bottom base, the microgroove structure including a plurality of microgrooves, and the plurality of microgrooves being provided on a surface of at least one of the vaporization top base and the vaporization bottom base in contact with the vaporization core body; and a liquid storage tank sleeved on the vaporization base.

Abstract: A vaporizer includes: a bottom plate having a first surface and a second surface arranged oppositely; a vaporization base arranged on and covering the first surface of the bottom plate and cooperating with the first surface of the bottom plate to form a vaporization cavity; a vaporization core accommodated in the vaporization cavity, the vaporization core heating and vaporizing liquid in the vaporization cavity when energized; and a liquid guiding assembly for absorbing liquid on the bottom plate, the liquid guiding assembly including: a first liquid guiding portion arranged on the first surface of the bottom plate and cooperating with the first surface of the bottom plate to form at least one first liquid guiding channel; and a second liquid guiding portion including at least one second liquid guiding channel, one end of the second liquid guiding channel being in communication with the first liquid guiding channel.

Abstract: A vaporizer includes: an air inlet; an air outlet; an airflow channel in communication with the air inlet and the air outlet, respectively, a vaporization core being arranged in the airflow channel; a first capillary liquid absorbing structure and a second capillary liquid absorbing structure, the first capillary liquid absorbing structure and the second capillary liquid absorbing structure being arranged in the airflow channel provided between the air inlet and the vaporization core, the first capillary liquid absorbing structure being arranged between the vaporization core and the second capillary liquid absorbing structure; and a gap between the first capillary liquid absorbing structure and the second capillary liquid absorbing structure so as to allow air entering from the air inlet to reach the vaporization core after flowing through the gap and the first capillary liquid absorbing structure sequentially.

Abstract: A vaporization device includes: an air inlet; an air outlet; a vaporization cavity in communication with the air inlet and the air outlet, a vaporization assembly being arranged in the vaporization cavity; and a first capillary liquid absorbing structure arranged on a part of the inner wall of the vaporization cavity close to the vaporization assembly. After the first capillary liquid absorbing structure absorbs an aerosol substrate, a temperature of the cavity wall of the vaporization cavity at a position where the first capillary liquid absorbing structure is located is lowerable with endothermic vaporization of the aerosol substrate.

Abstract: An air-curtain forming structure applicable to an electronic vaporization device includes: an airflow channel for delivering vapor; and a first air inlet channel in communication with the airflow channel and for introducing an external airflow into the airflow channel so as to form a blocking airflow between an inner wall of the airflow channel and the vapor.

Abstract: Provided is a light source device, including: a light-emitting chip arranged on a base plate and configured to emit first light; a light guide rod including first and second light guide portions, the first light guide portion including a light incident end surface, the first light entering the light guide rod through the light incident end surface and being transmitted to the second light guide portion after passing through the first light guide portion, and the second light guide portion including a light-outputting surface for outputting light; a first positioning member including a first groove for accommodating the light guide rod, being directly or indirectly fixed relative to the base plate; and a movable fixing assembly configured to fix, together with the groove of the first positioning member, the light guide rod along a radial direction of the light guide rod, and deforms when fixing the light guide rod.

Abstract: An atomizer includes: a housing, defining a first airflow passage through an inlet end and an outlet end; a liquid storage chamber, disposed within the housing; an atomizing assembly, disposed in a path of the first airflow passage, the atomizing assembly is in fluid connection with the liquid storage chamber; a sealing element, including a sealing body and an air compensating valve, the sealing body is configured to form a seal between the housing and the atomizing assembly, the air compensating valve includes a first side and a second side opposite to each other, the first side is located within the liquid storage chamber, the second side communicates with external air. The air compensating valve is opened when a pressure of the external air on the second side is greater than a pressure in the liquid storage chamber on the first side.

Abstract: A hotspot detection system that classifies a set of hotspot training data into a plurality of hotspot clusters according to their topologies, where the hotspot clusters are associated with different hotspot topologies, and classifies a set of non-hotspot training data into a plurality of non-hotspot clusters according to their topologies, where the non-hotspot clusters are associated with different topologies. The system extracts topological and non-topological critical features from the hotspot clusters and centroids of the non-hotspot clusters. The system also creates a plurality of kernels configured to identify hotspots, where each kernel is constructed using the extracted critical features of the non-hotspot clusters and the extracted critical features from one of the hotspot clusters, and each kernel is configured to identify hotspot topologies different from hotspot topologies that the other kernels are configured to identify.

Abstract: The present invention provides a novel pan-RAF kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also provides a use or method of the compound of formula (I) in the treatment or prevention of a disorder related to the activity of RAF and/or RAS kinase.

Abstract: An illumination device includes a light source and a first light guide. The first light guide includes a first light guide portion and a second light guide portion, and the second light guide portion includes a light-emitting surface. Light emitted by the light source couplingly enters the first light guide portion, and is emitted from the light-emitting surface of the second light guide portion. The cross-sectional area of the second light guide portion is perpendicular to the center line of the first light guide and gradually decreases along the optical axis direction of the light source. The light-emitting surface does not have rotational symmetry. By means of the illumination device, light rays emitted from the light-emitting surface are distributed unevenly in a space. Modifying the distribution of light emitted by the illumination device helps to reduce light loss and increase the utilization of the light.

Abstract: An illumination device includes a light source and a first light guide. The first light guide includes a first light guide portion and a second light guide portion, and the second light guide portion includes a light-emitting surface. Light emitted by the light source couplingly enters the first light guide portion, and is emitted from the light-emitting surface of the second light guide portion. The cross-sectional area of the second light guide portion is perpendicular to the center line of the first light guide and gradually decreases along the optical axis direction of the light source. The light-emitting surface does not have rotational symmetry. By means of the illumination device, light rays emitted from the light-emitting surface are distributed unevenly in a space. Modifying the distribution of light emitted by the illumination device helps to reduce light loss and increase the utilization of the light.

Abstract: A hotspot detection system that classifies a set of hotspot training data into a plurality of hotspot clusters according to their topologies, where the hotspot clusters are associated with different hotspot topologies, and classifies a set of non-hotspot training data into a plurality of non-hotspot clusters according to their topologies, where the non-hotspot clusters are associated with different topologies. The system extracts topological and non-topological critical features from the hotspot clusters and centroids of the non-hotspot clusters. The system also creates a plurality of kernels configured to identify hotspots, where each kernel is constructed using the extracted critical features of the non-hotspot clusters and the extracted critical features from one of the hotspot clusters, and each kernel is configured to identify hotspot topologies different from hotspot topologies that the other kernels are configured to identify.

Abstract: The present disclosure provides an adjustable external fixator which can be utilized in bone transport or bone lengthening. The adjustable external fixator includes a body, a positioning member, a bone coupling member, and a threaded rod. The body includes a slideway. At least one of the positioning member and the bone coupling member is slidably coupled to the slideway of the body.

Abstract: An arthroscopic positioning instrument is provided to overcome the problem of inconvenient operation of the modern arthroscopic positioning instrument. The arthroscopic positioning instrument includes a handle, a positioning member and a guiding cylinder is disclosed. The handle includes a finger holding member, a palm holding member and at least one connecting member. The palm holding member is connected to the finger holding member via the at least one connecting member. The finger holding member includes one end provided with an engaging portion and an arched guiding groove. The palm holding member does not intrude into a maximum axial range of the engaging portion. The positioning member includes an arched end and a hook end. The arched end is received in the arched guiding groove. The guiding cylinder is coupled with the engaging portion of the finger holding member.