Patents by Inventor Ru-Rong Ji

Ru-Rong Ji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING PRURITUS
    Publication number: 20160324868
    Abstract: A method of treating pruritus (itching) in a subject in need thereof is carried out by administering the subject an active agent in a treatment effective amount, wherein the active agent is a superoxide dismuate (SOD) mimetic. The SOD mimetic can be a complex of a metal (e.g., manganese) and an organic ligand, with suitable organic ligands including porphyrins, polyamines, salens, nitroxides, and fullerenes. Compositions for carrying out such methods are also described.
    Type: Application
    Filed: January 21, 2015
    Publication date: November 10, 2016
    Inventors: Ru-Rong Ji, Tong Liu, Ines Batinic-Haberle, David S. Warner, Kimberly C. Stone, James D. Crapo
  • NAV1.7 ANTIBODIES AND METHODS OF USING THE SAME
    Publication number: 20160237153
    Abstract: Disclosed herein is an antibody that binds to a voltage sensor paddle (VSP) of Nav1.7. Also disclosed herein are methods of treating pain, itch, neurogenic inflammation, or cough in a subject in need thereof. The methods include administrating the antibody to the subject.
    Type: Application
    Filed: September 5, 2014
    Publication date: August 18, 2016
    Inventors: Seok-Yong Lee, Ru-Rong Ji
  • Agents, compositions, and methods for treating pruritus and related skin conditions
    Patent number: 9241991
    Abstract: This invention relates generally to a therapeutic use of TLR3 and TLR7 inhibitors to treat or reduce pruritus in a subject.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: January 26, 2016
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Ru-Rong Ji, Temugin Berta, Zhen-Zhong Xu, Tong Liu, Chul-Kyu Park
  • Agents, Compositions, And Methods For Treating Pruritis And Related Skin Conditions
    Publication number: 20130266588
    Abstract: This invention relates generally to a therapeutic use of TLR3 and TLR7 inhibitors to treat or reduce pruritus in a subject.
    Type: Application
    Filed: October 21, 2011
    Publication date: October 10, 2013
    Applicant: BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Ru-Rong Ji, Temugin Berta, Zhen-Zhong Xu, Tong Liu, Chul-Kyu Park
  • METHOD FOR TREATING NEUROPATHIC PAIN
    Publication number: 20120245229
    Abstract: The invention describes a method to treat neuropathic pain and/or inflammatory pain, comprising the step of administering to a subject in need thereof an effective amount of a resolvin, such that neuropathic pain and or inflammatory pain is treated.
    Type: Application
    Filed: September 15, 2010
    Publication date: September 27, 2012
    Inventors: Ru-Rong Ji, Charles N. Serhan
  • Methods for inhibiting pain
    Publication number: 20080026003
    Abstract: The invention provides methods for the treatment or prevention of pain. The invention also provides screening methods for determining whether a compound inhibits IL-1? activity in the central nervous system of a mammal.
    Type: Application
    Filed: January 4, 2007
    Publication date: January 31, 2008
    Applicant: The General Hospital Corporation
    Inventors: Clifford Woolf, Tarek Samad, Ru-Rong Ji
  • Methods for inhibiting pain
    Publication number: 20040105859
    Abstract: The invention provides methods for the treatment or prevention of pain. The invention also provides screening methods for determining whether a compound inhibits IL-1&bgr; activity in the central nervous system of a mammal.
    Type: Application
    Filed: December 15, 2003
    Publication date: June 3, 2004
    Inventors: Clifford J Woolf, Tarek A Samad, Ru-Rong Ji