Patents by Inventor Ruben Sandoval

Ruben Sandoval has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240077161
    Abstract: A water pipe winterizing assembly includes a pipe has a female hose coupling for engaging a hose bib on a building. A heating unit is attached to the pipe and the heating unit heats the pipe when the heating unit is turned on to inhibit the hose bib and associated water pipes from freezing. An insulating pad is positioned around the pipe and the insulating pad is comprised of a thermally insulating material thereby inhibiting thermal communication between the pipe and ambient air. A cover is positionable over the hose bib and the pipe extends through the cover. A retainer extends through the cover and the retainer is positionable around the hose bib when the cover is positioned over the hose bib for retaining the cover over the hose bib.
    Type: Application
    Filed: September 2, 2022
    Publication date: March 7, 2024
    Inventor: Ruben Sandoval
  • Publication number: 20220354403
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Application
    Filed: April 25, 2022
    Publication date: November 10, 2022
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Patent number: 11337629
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: May 24, 2022
    Assignee: PHARMACOPHOTONICS, INC.
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Publication number: 20210379206
    Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard unmodified protein, colloid or crystalloid and a fluorescently-labeled protein, colloid or crystalloid of approximately the same molecular weight. The use of blood volume expanders to measure, adjust and maintain the level of blood volume in a patient also is described.
    Type: Application
    Filed: April 30, 2021
    Publication date: December 9, 2021
    Applicant: PharmacoPhotonics, Inc. d/b/a FAST BioMedical
    Inventors: Ruben Sandoval, JR., Erinn Sheridan Reilly, Daniel Meier
  • Patent number: 10994030
    Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard unmodified protein, colloid or crystalloid and a fluorescently-labeled protein, colloid or crystalloid of approximately the same molecular weight. The use of blood volume expanders to measure, adjust and maintain the level of blood volume in a patient also is described.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: May 4, 2021
    Assignee: PHARMACOPHOTONICS, INC.
    Inventors: Ruben Sandoval, Jr., Erinn Sheridan Reilly, Daniel Meier
  • Publication number: 20200100720
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Application
    Filed: November 22, 2019
    Publication date: April 2, 2020
    Applicant: PharmacoPhotonics, Inc. d/b/a FAST BioMedical
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Patent number: 10571397
    Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: February 25, 2020
    Assignee: PHARMACOPHOTONICS, INC.
    Inventors: Ruben Sandoval, Jr., Erinn Reilly, Daniel Meier
  • Publication number: 20200000941
    Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard unmodified protein, colloid or crystalloid and a fluorescently-labeled protein, colloid or crystalloid of approximately the same molecular weight. The use of blood volume expanders to measure, adjust and maintain the level of blood volume in a patient also is described.
    Type: Application
    Filed: March 25, 2019
    Publication date: January 2, 2020
    Inventors: Ruben Sandoval, JR., Erinn Sheridan Reilly, Daniel Meier
  • Patent number: 10485469
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Grant
    Filed: July 25, 2016
    Date of Patent: November 26, 2019
    Assignee: PHARMACOPHOTONICS, INC.
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Patent number: 10279052
    Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard umodified protein, colloid or crystalloid and a fluorescently-labeled protein colloid or crystalloid of approximately the same molecular weight. The use of blood volume expander to measure, adjust and maintain the level of blood volume in a patient also is described.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: May 7, 2019
    Assignee: Pharmacophotonics, Inc.
    Inventors: Ruben Sandoval, Jr., Erinn Sheridan Reilly, Daniel Meier
  • Publication number: 20190064068
    Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
    Type: Application
    Filed: August 29, 2018
    Publication date: February 28, 2019
    Inventors: Ruben Sandoval, JR., Erinn Reilly, Daniel Meier
  • Patent number: 10082465
    Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: September 25, 2018
    Assignee: Pharmacophotonics, Inc.
    Inventors: Ruben Sandoval, Jr., Erinn Reilly, Daniel Meier
  • Publication number: 20180256755
    Abstract: Methods of measurement of biometric indicators in a mammalian subject are described. Biometric indicators of interest include hematocrit, plasma volume, volume of distribution, and glomerular filtration rate. The methods are especially applicable to subjects with rapid blood loss and to subjects with unstable hematocrits. Hematocrit may be measured by administering an injectate with a dynamic fluorescent marker and a static fluorescent marker, or a single static marker with two fluorescent tags, into the vascular system of the subject, and monitoring the emission intensities of the markers or fluorescent tags over a period of time. Hematocrit may then be calculated using a calibrated spectrometric analyzer by determining the raw ratio of the markers at T0, calculating the apparent hematocrit, and applying a correction factor.
    Type: Application
    Filed: November 29, 2017
    Publication date: September 13, 2018
    Applicant: PHARMACOPHOTONICS, INC.
    Inventors: Daniel Meier, Bruce Molitoris, Erinn Sheridan, Ruben Sandoval
  • Publication number: 20180147302
    Abstract: Methods of measurement of biometric indicators in a mammalian subject are described. Biometric indicators of interest include hematocrit, plasma volume, volume of distribution, and glomerular filtration rate. The methods are especially applicable to subjects with rapid blood loss and to subjects with unstable hematocrits. Hematocrit may be measured by administering an injectate with a dynamic fluorescent marker and a static fluorescent marker, or a single static marker with two fluorescent tags, into the vascular system of the subject, and monitoring the emission intensities of the markers or fluorescent tags over a period of time. Hematocrit may then be calculated using a calibrated spectrometric analyzer by determining the raw ratio of the markers at T0, calculating the apparent hematocrit, and applying a correction factor.
    Type: Application
    Filed: November 29, 2017
    Publication date: May 31, 2018
    Applicant: PHARMACOPHOTONICS, INC.
    Inventors: Daniel Meier, Bruce Molitoris, Erinn Sheridan, Ruben Sandoval
  • Patent number: 9814788
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: November 14, 2017
    Assignee: PHARMACOPHOTONICS, INC.
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Publication number: 20170014065
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Application
    Filed: July 25, 2016
    Publication date: January 19, 2017
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Publication number: 20160346407
    Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard umodified protein, colloid or crystalloid and a fluorescently-labeled protein colloid or crystalloid of approximately the same molecular weight. The use of blood volume expander to measure, adjust and maintain the level of blood volume in a patient also is described.
    Type: Application
    Filed: February 6, 2015
    Publication date: December 1, 2016
    Inventors: Ruben Sandoval, Jr., Erinn Sheridan Reilly, Daniel Meier
  • Publication number: 20160266042
    Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
    Type: Application
    Filed: October 24, 2014
    Publication date: September 15, 2016
    Inventors: Ruben Sandoval, Jr., Erinn Sheridan, Daniel Meier
  • Patent number: 9398876
    Abstract: A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: July 26, 2016
    Assignee: Pharmacophotonics, Inc.
    Inventors: Exing Wang, Daniel Meier, Robert Bunch, Bruce Molitoris, Ruben Sandoval, Matthew Rubin
  • Publication number: 20140369936
    Abstract: Methods of measurement of biometric indicators in a mammalian subject are described. Biometric indicators of interest include hematocrit, plasma volume, volume of distribution, and glomerular filtration rate. The methods are especially applicable to subjects with rapid blood loss and to subjects with unstable hematocrits. Hematocrit may be measured by administering an injectate with a dynamic fluorescent marker and a static fluorescent marker, or a single static marker with two fluorescent tags, into the vascular system of the subject, and monitoring the emission intensities of the markers or fluorescent tags over a period of time. Hematocrit may then be calculated using a calibrated spectrometric analyzer by determining the raw ratio of the markers at T0, calculating the apparent hematocrit, and applying a correction factor.
    Type: Application
    Filed: February 15, 2013
    Publication date: December 18, 2014
    Inventors: Daniel Meier, Bruce Molitoris, Erinn Sheridan, Ruben Sandoval