Publication number: 20160318866
Abstract: The invention relates to novel substituted bipiperidinyl derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardiac vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, Raynaud's phenomenon, CREST syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.
Type:
Application
Filed:
December 16, 2014
Publication date:
November 3, 2016
Applicant:
Bayer Pharma Aktiengesellschaft
Inventors:
Eva Maria BECKER-PELSTER, Philipp BUCHGRABER, Anja BUCHMÜLLER, Karen ENGEL, Mark Jean GNOTH, Herbert HIMMEL, Raimund KAST, Joerg KELDENICH, Jürgen KLAR, Andreas KNORR, Dieter LANG, Niels LINDNER, Carsten SCHMECK, Rudolf SCHOHE-LOOP, Hanna TINEL, Hubert TRÜBEL, Frank WUNDER