Abstract: The invention concerns the provision of 7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b] indoles, useful, inter alia, as antidepressants, and intermediates for the preparation thereof. Also included in the invention are compositions containing said indoles and methods for the use of said indoles and indole compositions as antidepressants.

Abstract: A sheltered-type protection means for process instrumentation/automation, particularly quality measuring equipment for industrial processes with a hazardous environment and materials is described, which has a self-supporting housing with an extractable support member, on which is arranged at least one analyzer, a sample preparation means, an auxiliary material system and a unidirectional or bidirectional communications means for electrical signals. This arrangement permits a very compact construction and ensures that after extracting the support member unimpeded access to the individual components is possible. The invention also has the advantage that as a result of the small dimensions of the housing, it can be constructed in an extremely tight manner, so that the interior thereof is scavenged e.g. with an inert gas and can be kept under overpressure without leakage losses occurring.

Abstract: The present invention relates to certain new 7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole compound, to a process for their production and to their use as agents which have an influence on the central nervous system.The ring system according to the invention has not hitherto been described in the literature.

Abstract: The invention relates to a process for the production of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetoxyacetic acid (known to be useful as an antiphlogistic agent) which comprises reacting .alpha.-(4-chlorobenzoyl)-4-methoxyphenylhydrazine hydrochloride or sulphonate with laevulinoyloxyacetic acid and cyclizing the resulting hydrazone to obtain a product free from 1-benzoyl-5-methoxy-2-methyl-3-indolylacetoxyacetic acid.

Abstract: Novel 2-benzopyranone compounds of the formula ##STR1## wherein X is a 3,4,5-trimethoxybenzoyl group or a 3,4,5-trimethoxycinnamoyl group; and eachR individually is selected from the group consisting of alkylamino and dialkylamino in which one carbon atom in the alkyl moiety may be replaced by an oxygen atom and one hydrogen atom may be replaced by a hydroxyl group which may in turn be esterified with a 3,4,5-trimethoxybenzoyl or 3,4,5-trimethoxycinnamoyl group; amino substituted once or twice by alkenyl, aralkyl, or cycloalkyl; ora 4- to 7-membered N-containing heterocyclic ring linked through a nitrogen atom and which contains up to 3 hetero atoms, which heterocyclic ring may be substituted by phenyl, alkyl or hydroxyalkyl, wherein the hydroxy group may be esterfied by a 3,4,5-trimethoxy benzoyl or 3,4,5-trimethoxy cinnamoyl group;or a salt of each compound with a physiologically acceptable acid; possess outstanding activity as coronary dilators. Processes for producing such compounds are also disclosed.

Abstract: Novel 2-benzopyranone compounds of the formula ##STR1## wherein X is a 3,4,5-trimethoxybenzoyl group or a 3,4,5-trimethoxycinnamoyl group; and eachR individually is selected from the group consisting of alkylamino and dialkylamino in which one carbon atom in the alkyl moiety may be replaced by an oxygen atom and one hydrogen atom may be replaced by a hydroxyl group which may in turn be esterified with a 3,4,5-trimethoxybenzoyl or 3,4,5-trimethoxycinnamoyl group; amino substituted once or twice by alkenyl, aralkyl, or cycloalkyl; or a 4- to 7-membered N-containing heterocyclic ring linked through a nitrogen atom and which contains up to 3 hetero atoms, which heterocyclic ring may be substituted by phenyl, alkyl or hydroxyalkyl, wherein the hydroxy group may be esterified by a 3,4,5-trimethoxy benzoyl or 3,4,5-trimethoxy cinnamoyl group;Or a salt of each compound with a physiologically acceptable acid; possess outstanding activity as coronary dilators. Processes for producing such compounds are also disclosed.

Abstract: Process for the production of a compound of the formula ##STR1## in which R stands for a benzyl radical or the radical ##STR2## and X is hydrogen or represents one or more substituents, wherein a compound of the formula ##STR3## is condensed with a compound of the formula ##STR4## in which R and X have the meaning indicated, at temperatures of at least 100.degree. C on an inert solvent as reaction medium, with formation of free HCl. The products are useful as intermediates for production of the corresponding indole derivatives wherein R is replaced by hydrogen or --CH.sub.2 COOH, which are antiphlogistically active compounds.