Abstract: A line-of-sight direction tracking method includes: providing corneal reflection for an eye of a user by using a plurality of light sources, and capturing images including a face of the user by using a plurality of cameras; determining coordinates of a light source reflection point and coordinates of a pupil center in a world coordinate system by means of a human eye feature set acquired from the images including the face, based on hardware calibration parameters; determining a line-of-sight optical axis according to the coordinates of the light source reflection point and the coordinates of the pupil center, and reconstructing, based on the line-of-sight optical axis, a line-of-sight visual axis by means of a compensation angle; and determining a point of sight on a target object according to the line-of-sight visual axis and a position of the target object in the world coordinate system.

Abstract: A detector may be provided with a sensing element or an array of sensing elements, each of the sensing elements may have a corresponding gain element. A substrate may be provided having a sensing element and a gain element integrated together. The gain element may include a section in which, along a direction perpendicular to an incidence direction of an electron beam, a region of first conductivity is provided adjacent to a region of second conductivity, and a region of third conductivity may be provided adjacent to the region of second conductivity. The sensing element may include a section in which, along the incidence direction, a region of fourth conductivity is provided adjacent to an intrinsic region of the substrate, and the region of second conductivity may be provided adjacent to the intrinsic region.

Abstract: A detector may be provided with an array of sensing elements. The detector may include a semiconductor substrate including the array, and a circuit configured to count a number of charged particles incident on the detector. The circuit of the detector may be configured to process outputs from the plurality of sensing elements and increment a counter in response to a charged particle arrival event on a sensing element of the array. Various counting modes may be used. Counting may be based on energy ranges. Numbers of charged particles may be counted at a certain energy range and an overflow flag may be set when overflow is encountered in a sensing element. The circuit may be configured to determine a time stamp of respective charged particle arrival events occurring at each sensing element. Size of the sensing element may be determined based on criteria for enabling charged particle counting.

Abstract: The present disclosure describes an image forming element having a semiconductor chip with micro-electro-mechanical-system (MEMS) devices and voltage generators, each voltage generator being configured to generate a voltage used by one or more of the MEMS devices. A floating ground may be used to add a voltage to the voltage generated by the voltage generators. The semiconductor chip may include electrical connections, where each voltage generator is configured to provide the voltage to the one or more MEMS devices through the electrical connections. The MEMS devices may define a boundary in the semiconductor chip within which the MEMS devices, the voltage generators, and the electrical connections are located. Each MEMS device may generate an electrostatic field to manipulate an electron beamlet of a multi-beam charged particle microscope. The MEMS devices may be organized into groups based on a distance to a reference location (e.g., optical axis) in the semiconductor chip.

Abstract: Systems and methods for implementing a detector array are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first element and a second element, and a switching region therebetween configured to connect the first element and the second element. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy.

Abstract: Systems and methods for implementing a detector array are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first element and a second element. The detector comprises a switching element configured to connect the first element and the second element. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy.

Abstract: A mechanical structure for installing cover plates of a pasta machine includes at least two brackets arranged symmetrically; a plurality of cover plates arranged between the two brackets, two ends of each cover plate are respectively and detachably connected to the two brackets. The cover plates are integrally formed by sheet metal technology. The cover plates are connected/mounted to brackets respectively through a snap-on and/or a slide-on connection.

Abstract: A local coil may include: a wireless power receiver, for converting electrical energy to AC electricity, the electrical energy being wirelessly received from a power source; an AC-DC converter, for converting the AC electricity to first DC electricity having a first voltage; a DC-DC converter, for converting the first DC electricity to second DC electricity having a second voltage; a comparator, for comparing the first voltage and the second voltage, and generating a level signal on the basis of a comparison result; and a transmitter, for sending the level signal to the power source, such that the power source adjusts an output power of the electrical energy on the basis of the level signal. The wirelessly supplying of power to a local coil as well as power feedback control is achieved to advantageously increase energy transmission efficiency and system robustness.

Abstract: A detector may be provided with an array of sensing elements. The detector may include a semiconductor substrate including the array, and a circuit configured to count a number of charged particles incident on the detector. The circuit of the detector may be configured to process outputs from the plurality of sensing elements and increment a counter in response to a charged particle arrival event on a sensing element of the array. Various counting modes may be used. Counting may be based on energy ranges. Numbers of charged particles may be counted at a certain energy range and an overflow flag may be set when overflow is encountered in a sensing element. The circuit may be configured to determine a time stamp of respective charged particle arrival events occurring at each sensing element. Size of the sensing element may be determined based on criteria for enabling charged particle counting.

Abstract: Systems and methods for implementing a detector array are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first element and a second element. The detector comprises a switching element configured to connect the first element and the second element. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy.

Abstract: Systems and methods for implementing a detector array are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first element and a second element, and a switching region therebetween configured to connect the first element and the second element. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy.

Abstract: A detector may be provided with an array of sensing elements. The detector may include a semiconductor substrate including the array, and a circuit configured to count a number of charged particles incident on the detector. The circuit of the detector may be configured to process outputs from the plurality of sensing elements and increment a counter in response to a charged particle arrival event on a sensing element of the array. Various counting modes may be used. Counting may be based on energy ranges. Numbers of charged particles may be counted at a certain energy range and an overflow flag may be set when overflow is encountered in a sensing element. The circuit may be configured to determine a time stamp of respective charged particle arrival events occurring at each sensing element. Size of the sensing element may be determined based on criteria for enabling charged particle counting.

Abstract: Systems and methods for implementing a detector array are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first element and a second element. The detector comprises a switching element configured to connect the first element and the second element. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy.

Abstract: A mechanical structure for installing cover plates of a pasta machine includes at least two brackets arranged symmetrically; a plurality of cover plates arranged between the two brackets, two ends of each cover plate are respectively and detachably connected to the two brackets. The cover plates are integrally formed by sheet metal technology. The cover plates are connected/mounted to brackets respectively through a snap-on and/or a slide-on connection.

Abstract: Systems and methods for implementing a detector array are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first element and a second element. The detector comprises a switching element configured to connect the first element and the second element. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy.

Abstract: The present invention provides use of Tadalafil as a protein arginine methyltransferase 5 (PRMT5) inhibitor. The present invention finds out that Tadalafil is a PRMT5 inhibitor by virtually screening active compounds targeting PRMT5 based on crystal structure and information about active sites of PRMT5. The present invention not only confirms that Tadalafil can inhibit an enzymatic activity of PRMT5, but also confirms that Tadalafil alone can inhibit tumor growth in breast cancer and improve sensitivity to chemotherapy for breast cancer.

Abstract: A local coil may include: a wireless power receiver, for converting electrical energy to AC electricity, the electrical energy being wirelessly received from a power source; an AC-DC converter, for converting the AC electricity to first DC electricity having a first voltage; a DC-DC converter, for converting the first DC electricity to second DC electricity having a second voltage; a comparator, for comparing the first voltage and the second voltage, and generating a level signal on the basis of a comparison result; and a transmitter, for sending the level signal to the power source, such that the power source adjusts an output power of the electrical energy on the basis of the level signal. The wirelessly supplying of power to a local coil as well as power feedback control is achieved to advantageously increase energy transmission efficiency and system robustness.

Abstract: Detector modules, systems and methods for detecting signal beams are disclosed using a detector module and a support comprising a feedthrough. Furthermore, apparatuses, systems, and methods for sealing a vacuum system configured to provide an atmospheric environment and a vacuum chamber environment are disclosed. In some embodiments, a printed circuit board (PCB) comprising a first side for exposing to the atmospheric environment and a second side for exposing to the vacuum chamber environment and for covering an aperture in the vacuum chamber environment, wherein the second side is opposite to the first side. The apparatuses, systems, and methods may include a rigid body on the first side of the PCB and a device connected to the second side of the PCB and positioned on a portion of the PCB that covers the aperture. The PCB may be configured to provide an interface between the device and the rigid body.

Abstract: A power source supply system for a magnetic resonance imaging (MRI) apparatus that has multiple loads operating in a magnetic field environment, has an AC/DC conversion circuit that converts a supplied AC current to a first DC current having a predetermined first voltage, a branching element that supplies the first DC current in separate paths respectively to the multiple loads, a switching power source, disposed in each of the loads that converts the first DC current to a second DC current having a second voltage capable of being supplied to the load, with a switching frequency of the switching power source being set such that a positive integer frequency multiple thereof is offset from the Larmor frequency of the MRI apparatus.

Abstract: Detectors and detection systems are disclosed. According to certain embodiments, a substrate comprises a plurality of sensing elements including a first plurality of the sensing elements and a second plurality of the sensing elements, and a plurality of sections configured to connect the first plurality to an output, and connect the second plurality to an output. Switching regions may be provided between the sensing elements that are configured to connect two or more sensing elements. The switching region may be controlled based on signals generated in response to the sensing elements receiving electrons with a predetermined amount of energy and/or beam intensity.