Abstract: Provided is an apparatus, system and method for on-chip microfluids dispensing. The apparatus comprising a substrate; a plurality of first electrodes arranged one next to another on the substrate; a dielectric layer above and enclosing the plurality of first electrodes; and a second electrode on the substrate, wherein each of the plurality of first electrodes is in electric communication with a respective first driving signal input; wherein the second electrode is in electric communication with a second driving signal input; wherein the plurality of first electrodes define a continuous fluid path along a longitudinal direction for retaining microfluids, and wherein the second electrode is arranged within the continuous fluid path and defines a jetting position and an adjacent mixing position within the continuous fluid path.

Abstract: The present disclosure provides a control system of a buck converter, relating to the field of Internet of Things. The control system of a buck converter provided in an embodiment of the present disclosure includes a first control module, a second control module, and a mode selector. The first control module is turned on and the second control module is turned off through an analog current sensor in the mode selector when an IoT device switches from a transmission mode to a sleep mode or a standby mode, so that the first control module outputs a first voltage pulse to the driving and level shifter module, wherein a frequency of the first voltage pulse is determined by a frequency of a first clock in the first control module, and a width of the first voltage pulse is determined by a frequency of a second clock in the first control module.

Abstract: The present disclosure provides a control system of a buck converter, relating to the field of Internet of Things. The control system of a buck converter provided in an embodiment of the present disclosure includes a first control module, a second control module, and a mode selector. The first control module is turned on and the second control module is turned off through an analog current sensor in the mode selector when an IoT device switches from a transmission mode to a sleep mode or a standby mode, so that the first control module outputs a first voltage pulse to the driving and level shifter module, wherein a frequency of the first voltage pulse is determined by a frequency of a first clock in the first control module, and a width of the first voltage pulse is determined by a frequency of a second clock in the first control module.

Abstract: Provided is a digital microfluidic device for quick polymerase chain reaction. The digital microfluidic device includes an enclosed chamber for holding droplets comprising PCR mixtures. The chamber has an upper layer and a lower layer, which provide a top heater and a bottom heater contained in a thermal electrode respectively to form dual heaters. The lower layer further has an array of electrodes and a dielectric layer, e.g. Norland Optical adhesive 61, coating thereon. Such arrangement of the digital microfluidic device allows quick and homogeneous heating of droplets to lower the heating voltage, shorten the reaction time, and prevent the dielectric layer from breakdown during the thermal cycle.

Abstract: An exemplary embodiment of the present invention is a wireless power transmission circuit that provides power to a load of variable resistance with an alternating current (AC) power source induced at a secondary coil in a secondary side of the circuit by a primary coil in a primary side of the said circuit. The wireless power transmission circuit includes a switch-controlled capacitor (SCC) and a semi-active rectifier (SAR). The SCC connects to the AC power source. The SCC includes a first capacitor connected in parallel with two electrically controllable switches in series. The SAR connects to output of the SCC for rectifying the output of the SCC, wherein the SAR comprises a bridge circuit that includes two electrically controllable switches. A control angle of the SCC and a conduction angle of the SAR are regulated to provide a load impedance that matches the impedance of the coils.

Abstract: An exemplary embodiment of the present invention is a wireless power transmission circuit that that provides power to a load of variable resistance with an alternating current (AC) power source induced at a secondary coil in a secondary side of the circuit by a primary coil in a primary side of the said circuit. The wireless power transmission circuit includes a switch-controlled capacitor (SCC) and a semi-active rectifier (SAR). The SCC connects to the AC power source. The SCC includes a first capacitor connected in parallel with two electrically controllable switches in series. The SAR connects to output of the SCC for rectifying the output of the SCC, wherein the SAR comprises a bridge circuit that includes two electrically controllable switches. Both switches in the SCC are turned on for half a cycle and complement to each other and are turned off with a time delay relative to the zero cross points of the AC power source, and the time delay is a control angle of the SCC.

Abstract: The present disclosure discloses an enhancing agent and a kit for enhancing nucleic acid amplification reaction and a method for performing nucleic acid amplification reaction, relating to the field of biotechnology. The enhancing agent disclosed in the present disclosure has a domain capable of binding to fluorescent dye and a quenching group for quenching fluorescence emitted by the fluorescent dye bound to the domain binds. As the binding affinity between the above domain and the fluorescent dye is lower than the binding affinity between a target amplification product of nucleic acid amplification reaction and the fluorescent dye, the enhancing agent not only can reduce inhibition of high-concentration fluorescent dye to amplification reaction, but also can enhance signal intensity of the fluorescent dye in the nucleic acid amplification reaction based on microfluidic chip, improving reliability of application of the fluorescent dye as amplification indicator on the microfluidic chip.

Abstract: A flipping-capacitor rectifier circuit that enhances an output power of a piezoelectric energy harvester (PEH). The flipping-capacitor rectifier circuit includes a flipping capacitor, a plurality of switches, and an active rectifier. The flipping capacitor is connected in parallel with the PEH and forms at least three reconfiguration phases by turning on one or more of the switches. The active rectifier connects with the flipping capacitor in parallel and rectifies an AC voltage of the PEH. The flipping capacitor flips a voltage across a capacitor of the PEH to enhance the output power of the PEH by extracting power from the capacitor of the PEH.

Abstract: Provided is an apparatus, system and method for on-chip microfluids dispensing. The apparatus comprising a substrate; a plurality of first electrodes arranged one next to another on the substrate; a dielectric layer above and enclosing the plurality of first electrodes; and a second electrode on the substrate, wherein each of the plurality of first electrodes is in electric communication with a respective first driving signal input; wherein the second electrode is in electric communication with a second driving signal input; wherein the plurality of first electrodes define a continuous fluid path along a longitudinal direction for retaining microfluids, and wherein the second electrode is arranged within the continuous fluid path and defines a jetting position and an adjacent mixing position within the continuous fluid path.

Abstract: An incremental analog-to-digital converter (IADC) with a two-phase linear-exponential accumulation loop for improving the signal to noise distortion ratio (SNDR) and the dynamic range (DR) is disclosed. The linear-exponential IADC includes an analog modulator and a decimation filter. The analog modulator has an input for receiving the analog input voltage and an output. The analog modulator includes an integrator, an adder, a quantizer, a noise-coupling path, a data weighted averaging (DWA) circuit, and a digital-to-analog converter (DAC). The decimation filter has an input for receiving signals from the output of the analog modulator. The decimation filter includes a 1st order accumulator, an exponential accumulator, and a decimator. The linear-exponential IADC is configured to operate with a linear phase for suppressing the thermal noise and an exponential phase for boosting the SQNR.

Abstract: Provided is a digital microfluidic device for quick polymerase chain reaction. The digital microfluidic device includes an enclosed chamber for holding droplets comprising PCR mixtures. The chamber has an upper layer and a lower layer, which provide a top heater and a bottom heater contained in a thermal electrode respectively to form dual heaters. The lower layer further has an array of electrodes and a dielectric layer, e.g. Norland Optical adhesive 61, coating thereon. Such arrangement of the digital microfluidic device allows quick and homogeneous heating of droplets to lower the heating voltage, shorten the reaction time, and prevent the dielectric layer from breakdown during the thermal cycle.

Abstract: A palm-size portable ?NMR relaxometer system for performing multi-step multi-sample chemical/biological assays, comprising a PCB having a CMOS ?NMR transceiver and a DMF device integrated thereon. A portable magnet has an inner gap configured to at least partially receive the DMF device. The DMF device comprises a platform of electrodes including a sensing site and receives one or more samples for analysis at an electrode and automatically transports the one or more samples on individual paths sequentially to the sensing site, for performing sensing on each sample sequentially. A Butterfly coil disposed on the PCB and underneath the DMF device and is at least partially received in the inner gap. The Butterfly coil excites the sample at the ?NMR sensing site by transducing a magnetic field produced at the sensing site to an electrical signal which is processed by the CMOS ?NMR transceiver to produce an analytical signal.

Abstract: Provided is a microfluidic chip for generating a plurality of droplets comprising plural droplet-forming units serially connected together, an inlet for receiving the loading fluid and providing the loading fluid to the plural droplet-forming units, and an outlet for discharging the loading fluid remained after passing through the plural droplet-forming units. Each of the individual droplet-forming unit include an inflow channel, a neck channel, a droplet-forming well and a bypass channel therearound, a restricted flow port element, and an outflow channel, the arrangement of which allows the microfluidic chip to form robust and stable droplets for reliable and flexible drug screening assays using a small sample input size.

Abstract: A flipping-capacitor rectifier circuit that enhances an output power of a piezoelectric energy harvester (PEH). The flipping-capacitor rectifier circuit includes a flipping capacitor, a plurality of switches, and an active rectifier. The flipping capacitor is connected in parallel with the PEH and forms at least three reconfiguration phases by turning on one or more of the switches. The active rectifier connects with the flipping capacitor in parallel and rectifies an AC voltage of the PEH. The flipping capacitor flips a voltage across a capacitor of the PEH to enhance the output power of the PEH by extracting power from the capacitor of the PEH.

Abstract: Bidirectional wireless power transfer (WPT) manages to provide a first aid to a mobile device that is running out of energy in urgent circumstances. To facilitate bidirectional WPT with minimum additional cost, a WPT transceiver reconfigurable for performing WPT and wireless power reception (WPR) is provided. The transceiver is reconfigurable between a differential class-D power amplifier (PA) and a full-wave rectifier. A maximum current charging mode (MCCM) is used to maximize a battery-to-battery (B2B) charging efficiency, by directly charging the loading battery with the rectifier, and by powering the PA with the sourcing battery. No output voltage or current regulation is used. Then the number of cascaded charging stages is reduced from five in the conventional design to three.

Abstract: According to one aspect of the present disclosure, a control-engaged electrode-driving method for droplet actuation is provided. The method includes, a first pulse is provided to a first electrode for kicking off a droplet till a centroid of the droplet reaching a centroid of the first electrode. A second pulse is provided to a second electrode when a leading edge of the droplet reaching the second electrode.

Abstract: A method achieves minimum limit cycle oscillation (LCO) amplitude of a digital low dropout regulator (D-LDO) by adding auxiliary unit power transistors in parallel with the main PMOS array with selected unit strength and LCO mode. An improved D-LDO with reduced LCO amplitude includes an auxiliary power transistor array in selected strength driven by an output of a comparator in parallel with a main power transistor array.

Abstract: According to one aspect of the present disclosure, a control-engaged electrode-driving method for droplet actuation is provided. The method includes, a first voltage is provided to a first electrode for licking off a droplet. A second voltage is naturally discharged to a third voltage for maintaining a droplet movement. A fourth voltage is provided to the first electrode for accelerating the droplet. Naturally discharging from the second voltage to the third voltage and providing the fourth voltage to the first electrode are repeated. The first voltage is provided to a second electrode when a centroid of the droplet reaching a centroid of the first electrode. Naturally discharging from the second voltage to the third voltage and providing the fourth voltage to the second electrode are repeated.

Abstract: According to one aspect of the present disclosure, a digital microfluidic system is provided. The digital microfluidic system includes a device, a control electronics, a field programmed gate array (FPGA), and a computer. The device includes a droplet on an electrode array, where the electrode array includes a plurality of electrodes. The control electronics connects to the device and provides an actuation pulse to the electrodes, where the control electronics generates a capacitance-derived frequency signal. The FPGA connects to the control electronics and collects the capacitance-derived frequency signal. The computer connects to the FPGA, the computer uses a frequency of the capacitance-derived frequency signal to calculate a precise droplet position and generates a duration voltage signal.

Abstract: A mixed signal controller for a power quality compensator includes an analog circuit, an analog-to-digital converter (ADC), and a digital circuit. The analog circuit amplifies an input signal from the power quality compensator by a gain factor and outputs an analog signal, which is converted to a digital signal by the ADC. The digital circuit receives the digital signal, calculates the reference compensating current of each phase and then generates a trigger signal via hysteresis PWM to the power quality compensator. The digital circuit includes an evaluation circuit that calculates a value of the system total harmonic distortion after the power quality compensator compensates power and adjusts the gain factor when the value of the system total harmonic distortion reaches a predetermined threshold.