Abstract: In various embodiments, a computer-implemented method for generating a multi-objective model shared between multiple participants comprises receiving a first input associated with a first selectable component in a set of pre-defined selectable components associated with a shared design model, where the first selectable component is a first component type that is associated with a first persona in a plurality of personas, and each persona includes a distinct set of design goals that the shared design model represents in a multi-objective design problem, in response to the first input, modifying the shared design model to generate a modified shared design model that includes the first selectable component, and generating, based on the modified shared design model, a set of candidate design solutions that satisfy the distinct sets of design goals, where each candidate design solution includes additional selectable components of a second component type.

Abstract: In various embodiments, a computer-implemented method comprises receiving, during a real-time collaboration session, a first input associated with a first selectable component, where the first selectable component is included in a set of pre-defined selectable components associated with a shared design model, and the first selectable component is a first component type that includes a first set of characteristics, in response to receiving a confirmation of the first input, modifying the shared design model to generate a modified shared design model, where the modified shared design model includes the first selectable component, computing, based on the modified shared design model, a set of metrics including a first behavioral metric, computing, based on the set of metrics, a first collaboration score for a first participant and at least one other participant, and displaying a design space that includes the modified shared design model and the first collaboration score.

Abstract: A method, computer system, and a computer program product for performing an interactive outcome analysis is provided. The present invention may include generating, by a computer, a first estimation outcome from a first plurality of input conditions. The present invention may include generating, by the computer, a parallel estimation outcome from a second plurality of input conditions, wherein at least one of said input conditions in said first plurality of input conditions is different from any of said second plurality of input conditions. The present invention may include selecting, by the computer, either said first or said parallel estimation outcome by analyzing said outcomes with one another and with a target goal outcome.

Abstract: The invention encompasses novel dihydroquinoxalinone compounds with significantly improved water solubility and reduced toxicity to achieve higher therapeutic indexes and the treatment of cancer, virus infections, and inflammation using the same.

Abstract: A display panel includes pixel circuits, and the pixel circuit includes: a driving sub-circuit, a fourth sub-circuit and a first reset sub-circuit. The driving sub-circuit includes a driving transistor and a storage capacitor. The driving transistor includes a gate and an active pattern including a source portion and a drain portion. The storage capacitor includes a first storage electrode sharing a same electrode with the gate and a second storage electrode used to be connected to a first voltage signal line. The fourth sub-circuit is configured such that the drain portion and the gate are connected when being turned on. The first reset sub-circuit includes a first active pattern, which is arranged in a same layer as the active pattern and includes a first source portion being used to be connected to a first initialization signal line and a first drain portion being connected to the drain portion.

Abstract: A key-value engine of a storage system may perform a restart recovery after a system failure. The key-value engine may read a metadata log to locate a latest system checkpoint, and load a page mapping table from the latest system checkpoint. The key-value engine may replay to apply changes to the page mapping table from a system transaction log starting from a system transaction replay starting point. The key-value engine may further form one or more read-only replicas using an underlying file stream opened in a read-only mode during the recovery after the system failure to further facilitate fast recovery and provide fast response to user transactions that conduct read only transactions after the system failure.

Abstract: A method for managing a region tag comprises: acquiring region identifier information of a geographic region; acquiring an attribute evaluation tag of the geographic region by a user in the geographic region and a time identifier of the attribute evaluation tag; integrating the region identifier information, the attribute evaluation tag, and the time identifier thereof into a region tag of the geographic region; clustering region tags to generate a region time period tag of the geographic region for a time period based on that each region tag comprises the region identifier information of the geographic region and a time identifier within the time period, wherein the region time period tag of the geographic region for the time period corresponds to a function attribute of the geographic region for the time period; and outputting region time period tags of the geographic region for time periods, respectively.

Abstract: This application discloses a communication method, a communications apparatus and a communications system, to resolve a problem that a terminal cannot quickly resume a communication connection to a secondary node. The method includes: sending a first message to a first master node to request state transition of a terminal from a third mode to a connected mode; receiving a second message from the first master node, where the second message comprises a first security parameter and SCG configuration information, and completing, based on the first security parameter and the SCG configuration information, a communication connection to the secondary node.

Abstract: The silicon carbide device includes a gate trench, a source trench, a gate, a source and a p-type well region. The gate trench and the source trench are disposed in a silicon carbide substrate and alternately spaced apart. The gate disposed in the gate trench is isolated from a second n-type silicon carbide layer by a first insulating layer, and the gate is isolated from a p-type silicon carbide layer and a third n-type silicon carbide layer by a second insulating layer. The source disposed in the source trench is connected to the p-type silicon carbide layer and the third n-type silicon carbide layer, and the source is isolated from the second n-type silicon carbide layer by a third insulating layer. The p-type well region is disposed at a bottom of the source trench, where the p-type well region is connected to the source.

Abstract: Systems and methods discussed herein, based on a key-value data store including multiple-tiered sorted data structures in memory and storage, implement granularly timestamped concurrency control. The multiple-tiering of the key-value data store enables resolving the snapshot queries by returning data record(s) according to granularly timestamped snapshot lookup instead of singularly indexed snapshot lookup. Queries return a merged collection of records including updates from data structures in memory and in storage, such that a persistent storage transaction may refer to non-committed updates up to a timeframe defined by the snapshot read timestamp. This way, inconsistency is avoided that would result from merely reading data records committed in storage, without regard as to pending, non-committed updates thereto.

Abstract: The present disclosure relates to the technical field of genetic engineering, in particular to a siRNA of an angiopoietin like 3 (ANGPTL3) and a use thereof. The inventor of the present disclosure targets to ANGPTL3 by designing an appropriate specific small interfering RNA sequence and a siRNA conjugate, and reduce the expression of an ANGPTL3 protein by degrading a transcript of an ANGPTL3 gene in a cell. Therefore, the siRNA provided in the present disclosure may be used to prevent and/or treat a dyslipidemia disease.

Abstract: A charge pump comprises two bridge arms coupled in parallel, two capacitors, and a control circuit. Each bridge arm has two pairs of switches coupled in series, each pair of switches having two switches coupled in series through a common node. Each capacitor is connected between the two common nodes of the corresponding bridge arm. The control circuit provides a mode signal by comparing an output voltage of the charge pump with two threshold voltages via a hysteretic comparison, and provides two control signals with opposite logic states based on the mode signal to control each pair of the switches to work complementarily, wherein the logic states of the control signals flip in response to transiting from a first status to a second status of the mode signal, and maintain in response to transiting from the second status to the first status of the mode signal.

Abstract: A pressure-resistant hull for a submersible, includes unit hulls, reinforcing ribs, connecting channels, and closure heads. A plurality of unit hulls are provided, and are sequentially strung together spiralling upward or spiralling downward, the closure heads being arranged on the unit hulls at the first position and the last position respectively, an observation window being provided on each unit hull respectively, adjacent two unit hulls in a horizontal direction being respectively connected by means of a reinforcing rib, and at least two connecting channels being provided between adjacent two rings of the unit hulls in the vertical direction. The design method includes using a spiral joining structure to facilitate organic adjustment of the number of unit hulls, thus having better utilization of space and aiding to greatly expand the space. The sensitivity of the limit load to defects is low, increasing axial rigidity, improving the overall pressure-resistive ability.

Abstract: In an approach to efficient model adjustment utilizing a dual model system, one or more computer processors create a subset of a dataset utilizing a trained primary model; create a secondary model based on the created subset of the dataset; calculate a confidence of a case utilizing the trained primary model, wherein the confidence is a robustness indicator of a model indicating a capacity of the model to meet or exceed performance when applied to the dataset; responsive to the calculated confidence not exceeding a confidence threshold, generate a score of the case utilizing the created secondary model; responsive to an incorrect classification, update the created subset of the dataset with the case; retrain the secondary model utilizing the updated subset of the dataset.

Abstract: A pixel circuit, driving method for same and display apparatus are provided. The pixel circuit includes a driving sub-circuit, writing sub-circuit, compensation sub-circuit, first reset sub-circuit, first and second emitting control sub-circuits, and emitting element. The compensation sub-circuit writes signal of third node into first node under control of third scanning signal terminal, and compensates first node under control of third scanning signal terminal and first voltage terminal. The first reset sub-circuit writes signal of first initial signal terminal into third node under control of first scanning signal terminal and first emitting control signal terminal. The second emitting control sub-circuit provides signal of first voltage terminal for second node under control of second emitting control signal terminal.

Abstract: A ramp buffer circuit includes an input device having an input coupled to receive a ramp signal. A bias current source is coupled to an output of the input device. The input device and the bias current source are coupled between a power line and ground. An assist current source is coupled between the output of the input device and ground. The assist current source is configured to conduct an assist current from the output of the input device to ground only during a ramp event generated in the ramp signal.

Abstract: A communication method relates to a paging mechanism applied for a radio access network, including: a centralized unit sends a paging message to a distributed unit, where the paging message carries indication information indicates that the paging is paging originated from a core network or the paging is paging originated from a radio access network; and the distributed unit determines, according to the indication information, that the paging is paging originated from the core network or the paging is paging originated from the radio access network.

Abstract: Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).

Abstract: A manufacturing method of a semiconductor super-junction device includes the following steps: An n-type substrate is etched in a self-aligning manner using a first insulating layer and a second insulating layer as a mask to form a second groove in the n-type substrate. A gate structure is formed in the second groove.

Abstract: The invention relates to the field of flow batteries, and in particular relates to a neutral zinc iron flow battery and the use thereof. The neutral zinc iron flow battery comprises a negative electrode electrolyte solution and a positive electrode electrolyte solution, wherein a negative electrode electrolyte in the negative electrode electrolyte solution comprises a first ferrous salt and a zinc salt, the molar ratio of the first ferrous salt to the zinc salt is 0.01 to 0.25:1, wherein the first ferrous salt is based on Fe2?, and the zinc salt is based on Zn2+.