Abstract: The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of rasagiline or the pharmaceutically acceptable salt thereof, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, rasagiline or the pharmaceutically acceptable salt thereof and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of rasagiline or the pharmaceutically acceptable salt thereof, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.

Abstract: The present invention discloses an economical and disposable cleaning tool which may be prepared by a simplified manufacturing process involving a reduced number of steps. The cleaning tool comprises a cleaning pad and a handle, the cleaning pad having a pocket for receiving the handle. The cleaning pad may be provided with a top sheet and a fiber bundle. The top sheet is folded over and bonded to provide a cleaning portion and a back portion, and the fiber bundle is disposed on the cleaning portion. The cleaning portion and the back portion of the folded sheet are bonded together forming the pocket for the handle to be disposed therein. The handle may include a hinge to enable the handle to be repeatedly folded over for convenient storage or easily extended for use.

Abstract: A method for modifying Parkinson's disease by periodically administering a pharmaceutical composition comprising a therapeutically effective amount of rasagiline or a pharmaceutically acceptable salt of rasagiline to the patient, thereby modifying the disease. The method includes reducing the rate of progression; delaying the need for symptomatic anti-Parkinsonian therapy; reducing the risk of a Parkinson's disease patient requiring symptomatic anti-Parkinsonian therapy; and reducing the functional decline.

Abstract: The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of rasagiline or the pharmaceutically acceptable salt thereof, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, rasagiline or the pharmaceutically acceptable salt thereof and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of rasagiline or the pharmaceutically acceptable salt thereof, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.

Abstract: The subject invention provides a method for treating amyotrophic lateral sclerosis (ALS) in a subject in need of such treatment comprising administering to the subject R(+)-N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof alone or in combination with 2-amino-6-trifluoromethoxy benzothiazole in amounts effective to treat ALS in the subject.

Abstract: The present invention discloses an economical and disposable cleaning tool which may be prepared by a simplified manufacturing process involving a reduced number of steps. The cleaning tool comprises a cleaning pad and an implementing means, the cleaning pad having a pocket for receiving the implementing means. The cleaning pad may be provided with a top sheet and a fiber bundle. The top sheet is folded over and bonded to provide a cleaning portion and a back portion, and the fiber bundle is disposed on the cleaning portion. The cleaning portion and the back portion of the folded sheet are bonded together forming the pocket for a handle to be disposed therein. The handle may include a hinge to enable the handle to be repeatedly folded over for convenient storage or easily extended for use.

Abstract: Disclosed are methods for the treatment of Restless Legs Syndrome comprising administering an amount of R(+)-N-propargyl-1-aminoindan or a pharmaceutically acceptable salt thereof.

Abstract: The present invention discloses an economical and disposable cleaning tool which may be prepared by a simplified manufacturing process involving a reduced number of steps. The cleaning tool comprises a cleaning pad and an implementing means, the cleaning pad having a pocket for receiving the implementing means. The cleaning pad may be provided with a top sheet and a fiber bundle. The top sheet is folded over and bonded to provide a cleaning portion and a back portion, and the fiber bundle is disposed on the cleaning portion. The cleaning portion and the back portion of the folded sheet are bonded together forming the pocket for a handle to be disposed therein. The handle may include a hinge to enable the handle to be repeatedly folded over for convenient storage or easily extended for use.

Abstract: The subject invention provides methods of treating a subject afflicted with Parkinson's disease, memory disorder, depression, hyperactive syndrome, Attention Deficit Disorder, dementia, brain ischemia, stroke, head trauma injury, spinal trauma injury, neurotrauma, neurodegenerative disease, neurotoxic injury, multiple sclerosis, nerve damage, affective illness, schizophrenia or symptoms of withdrawal from an addictive substance, using the mesylate salt of R(+)-N-propargyl-1-aminoindan.

Abstract: A container for one-handed pop-up dispensing plural wiping sheets. The container comprises a housing having a hollow interior in which an array of wiping sheets is disposed. The housing includes an aesthetically pleasing opening whose perimeter defines a non-regular shaped icon representing a realistic, fanciful or otherwise ornamental object. The opening has a first portion and a second portion. The first portion is of sufficient size and shape to enable an adult to extend his/her fingers therethrough to grasp one sheet of the array to pull the sheet into it and then slide the sheet into the second portion. The second portion frictionally engage the sheet slid into it to cause that sheet to be separated from the remaining sheets in the array to remove that sheet from the container.

Abstract: A container for one-handed pop-up dispensing plural wiping sheets. The container comprises a housing having a hollow interior in which an array of wiping sheets is disposed. The housing includes an aesthetically pleasing opening whose perimeter defines a non-regular shaped icon representing a realistic, fanciful or otherwise ornamental object. The opening has a first portion and a second portion. The first portion is of sufficient size and shape to enable an adult to extend his/her fingers therethrough to grasp one sheet of the array to pull the sheet into it and then slide the sheet into the second portion. The second portion frictionally engage the sheet slid into it to cause that sheet to be separated from the remaining sheets in the array to remove that sheet from the container.

Abstract: The disclosure describes compositions, such as absorbent article topsheets or undersheets, that on its bodyside surfaces comprises an anionic surfactant-bound polymeric biguanide or an anionic surface-bound polymeric biguanide that can dissociate from the article so as to attack bacteria on the wearer's skin.

Abstract: The subject invention provides methods of treating a subject afflicted with Parkinson's disease, memory disorder, depression, hyperactive syndrome, Attention Deficit Disorder, dementia, brain ischemia, stroke, head trauma injury, spinal trauma injury, neurotrauma, neurodegenerative disease, neurotoxic injury, multiple sclerosis, nerve damage, affective illness, schizophrenia or symptoms of withdrawal from an addictive substance, using the mesylate salt of R(+)-N-propargyl-1-aminoindan.

Abstract: A closure tab is provided and includes a first substrate. A second substrate is adhesively attached to the first substrate. The second substrate has mechanical closure material formed thereon. A compression bond pattern is applied to the first substrate and the second substrate. The compression bond pattern includes at least one outwardly extending protrusion. The compression bond pattern may include, for example, circular bond points, stripes, or a decorative element. A method is also provided wherein the second substrate is compressed onto the first substrate by a patterned roller. The second substrate may be compressed onto the first substrate by a plurality of pins spaced in alternating offset rows.

Abstract: A container for one-handed pop-up dispensing plural wiping sheets. The container comprises a housing having a hollow interior in which an array of wiping sheets is disposed. The housing includes an aesthetically pleasing opening whose perimeter defines a non-regular shaped icon representing a realistic, fanciful or otherwise ornamental object. The opening has a first portion and a second portion. The first portion is of sufficient size and shape to enable an adult to extend his/her fingers therethrough to grasp one sheet of the array to pull the sheet into it and then slide the sheet into the second portion. The second portion frictionally engage the sheet slid into it to cause that sheet to be separated from the remaining sheets in the array to remove that sheet from the container.

Abstract: The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson's disease, a memory disorder, dementia, depression, hyperactive syndrome, an effective illness, a neurodegenerative disease, a neurotoxic injury, stroke, brain ischemia, a head trauma injury, a spinal trauma injury, neurotrauma, schizophrenia, an attention deficit disorder, multiple sclerosis, or withdrawal symptoms, using R(+)-N-propargyl-1-aminoindan or the pharmaceutically acceptable salt of the subject invention. The subject invention further provides a method of preventing nerve damage in a subject. Finally, the subject invention provides methods of preparing R(+)-N-propargyl-1-aminoindan, a salt thereof, and racemic N-propargyl-1-aminoindan.

Abstract: Absorbent articles that have wetness indicator graphics positioned thereon are disclosed, whereby the articles preferably include diapers, training pants, and adult incontinence products. The article includes a character graphic positioned in a waist region of the article, and a wetness indicator graphic that may be positioned in a crotch region. The character graphic is related to the wetness indicator graphic. The arrangement of the respective graphics preferably allow a caregiver to interact with a child to promote toilet training.

Abstract: The disclosure describes compositions, such as absorbent article topsheets or undersheets, that on its bodyside surfaces comprises an anionic surfactant-bound polymeric biguanide or an anionic surface-bound polymeric biguanide that can dissociate from the article so as to attack bacteria on the wearer's skin.

Abstract: The subject invention provides an immediate release tablet comprising the following components: a) a uniform admixture of an active ingredient selected from the group consisting of valproic sodium acid, a pharmaceutically acceptable salt or ester of valproic acid, divalproex sodium, valpromide and a compound having the structure: 1

Abstract: The subject provides a sustained release tablet comprising the following components: a) a uniform admixture of an active ingredient selected from the group consisting of valproic sodium acid, a pharmaceutically acceptable salt or ester of valproic acid, divalproex sodium, valpromide and a compound having the structure: 1