Patents by Inventor Ryan Craig

Ryan Craig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100272677
    Abstract: Compounds having the formula I wherein R1, R2, R3, R4, R5a, R5b, R5c and R6 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Application
    Filed: April 23, 2010
    Publication date: October 28, 2010
    Inventors: Eun Kyung Lee, Ryan Craig Schoenfeld, Francisco Xavier Talamas
  • Patent number: 7803830
    Abstract: The present invention provides compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: September 28, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: Pravin Iyer, Matthew C. Lucas, Ryan Craig Schoenfeld, Marzia Villa, Robert James Weikert
  • Patent number: 7754721
    Abstract: Compounds of the formula: or pharmaceutically acceptable salts thereof, wherein m, n, X, Y, Z, Ar, R1, R2, R3, R4, R5, R6 and R7 are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: July 13, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: David Scott Carter, Ryan Craig Schoenfeld, Robert James Weikert
  • Publication number: 20100158860
    Abstract: Compounds having the formula I wherein A, R1, R2, R3, R4a, R4b, R4c, R5, R6, R7a, R7b, Ar1, Rc, Rd, Re, Rf, X, n and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Application
    Filed: December 14, 2009
    Publication date: June 24, 2010
    Inventors: Sandra Steiner, Jim Li, Ryan Craig Schoenfeld, Francisco Xavier Talamas
  • Patent number: 7662265
    Abstract: Methods are provided for making bipolar electrochemical devices, such as batteries, using electrophoresis. A bipolar device is assembled by applying a field that creates a physical separation between two active electrode materials, without requiring insertion of a discrete separator film or electrolyte layer.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: February 16, 2010
    Assignees: Massachusetts Institute of Technology, A123 Systems, Inc.
    Inventors: Yet-Ming Chiang, Benjamin Hellweg, Richard K. Holman, Steven M. Tobias, Dong-Wan Kim, Ryan Craig Wartena
  • Publication number: 20100021423
    Abstract: Compounds having the formula I wherein R1, R2, R3, R4a, R4b, R4c, R5, R6, R9 and n are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Application
    Filed: July 22, 2009
    Publication date: January 28, 2010
    Inventors: Kenneth Albert Brameld, David Scott Carter, Elbert Chin, Javier de Vicente Fidalgo, Jim Li, Ryan Craig Schoenfeld, Eric Brian Sjogren, Francisco Xavier Talamas
  • Publication number: 20100016312
    Abstract: This application discloses compounds of generic Formula I: or pharmaceutically acceptable salts thereof, wherein A, R1, R2, R3, R4, Q, X, Y, m, p, and q are defined as described herein, useful for treatment of diseases associated with monoamine reuptake inhibitors. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Application
    Filed: July 15, 2009
    Publication date: January 21, 2010
    Inventors: Eun Kyung Lee, Ryan Craig Schoenfeld, Robert James Weikert
  • Publication number: 20090318493
    Abstract: Aryl and heteroaryl ketone compounds substituted with pyrrolidines and piperidines, that modulate serotonin norepinephrine and/or dopamine neurotransmission. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Application
    Filed: June 17, 2009
    Publication date: December 24, 2009
    Inventors: Pravin Iyer, Clara Jeou Jen Lin, Matthew C. Lucas, Stephen M. Lynch, Ann Marie Madera, Kerem Erol Ozboya, Ryan Craig Schoenfeld, Robert James Weikert
  • Patent number: 7622462
    Abstract: Compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ar, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, methods of preparing the compounds, and method of using the compounds for treatment of monoamine reuptake inhibitor-mediated diseases.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: November 24, 2009
    Assignee: Roche Palo Alto LLC
    Inventors: Ryan Craig Schoenfeld, Robert James Weikert
  • Publication number: 20090247568
    Abstract: This application discloses aminopiperidinyl compounds of generic Formulae I-II: or pharmaceutically acceptable salts thereof, wherein m, r, Q1, Q2, Q3, R, Ra, R1, R2a, R2b, and R3 are defined as described herein, useful for treatment of diseases associated with monoamine reuptake inhibitors. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 1, 2009
    Inventors: Pravin Iyer, Matthew C. Lucas, Ryan Craig Schoenfeld, Robert James Weikert
  • Publication number: 20090242455
    Abstract: A punch-through gift container for use in party and game play environments providing in one embodiment an enclosed container comprising a rigid backwall (40), rigid sidewalls (50 and 51), and an internally positioned matrix of interlocking rigid partitions (30 and 32), creating within the container a plurality of compartments (02). The front wall of the container comprises a thin fungible wrapper (10) affixed to the front of the container, with a plurality of aiming targets (20) adorned on the exterior of the wrapper to indicate the center of each compartment contained therein. Gifts placed within the compartments of the container are retrieved from the chosen compartment by punching or otherwise breaking the wrapper through the aiming target corresponding to the chosen compartment. Other embodiments are described and shown.
    Type: Application
    Filed: December 13, 2008
    Publication date: October 1, 2009
    Inventors: Russell Blake Adams, Ryan Craig Adams
  • Publication number: 20090209553
    Abstract: Compounds of the formula: or pharmaceutically acceptable salts thereof, wherein Ar, R1, R2, R3 and R4 are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Application
    Filed: February 12, 2009
    Publication date: August 20, 2009
    Inventors: David Scott Carter, Matthew C. Lucas, Ryan Craig Schoenfeld, Robert James Weikert
  • Publication number: 20090099236
    Abstract: The present invention provides compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Application
    Filed: October 8, 2008
    Publication date: April 16, 2009
    Inventors: Pravin Iyer, Matthew C. Lucas, Ryan Craig Schoenfeld, Marzia Villa, Robert James Weikert
  • Patent number: 7491821
    Abstract: Compounds of formula 1 are modulators of P2X3 useful for the treatment of pain and genitourinary, gastrointestinal, and respiratory disorders: wherein R1 is —C(?S)CH3, pyridyl, pyrimidinyl, pyrazinyl, thiazolyl, furyl, furylcarbonyl, acetyl, or carbamoyl; R2a and R2b are independently H, methyl, or ethyl; R3 is H or methyl; Y is a bond, —(CR4R5)n— or —CR4?CR5—; wherein R4 and R5 are each independently H or methyl and n is 1 or 2; X is N or CH; A is phenyl, 5-membered heterocyclyl, or 6-membered heterocyclyl; R6, R7 and R8 are each independently H, halo, lower alkyl, cycloalkyl, alkylthio, alkylthio-lower alkyl, alkylsulfonyl-lower alkyl, di(lower alkyl)amino-lower alkyl, morpholinyl-lower alkyl, 4-methyl-piperazinyl-methyl, trifluoromethyl, pyridyl, tetrazolyl, thiophenyl, phenyl, biphenyl, or benzyl (where thiophenyl, phenyl and benzyl are substituted with 0-3 lower alkyl, halo, sulfonamido, trifluoromethyl, lower alkoxy or lower alkylthio) or R6 and R7 together form a 5-membered or 6-membered carbocycl
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: February 17, 2009
    Assignee: Roche Palo Alto LLC
    Inventors: Christine E. Brotherton-Pleiss, Michael Patrick Dillon, Shelley K. Gleason, Clara Jeou Jen Lin, Ryan Craig Schoenfeld, Marzia Villa, Yansheng Zhai
  • Patent number: 7446118
    Abstract: The present invention provides compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd and Re are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: November 4, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Pravin Iyer, Matthew C. Lucas, Ryan Craig Schoenfeld, Marzia Villa, Robert James Weikert
  • Publication number: 20080146607
    Abstract: Compounds of the formula: or pharmaceutically acceptable salts thereof, wherein m, n, Ar, R1, R2, Ra and Rb are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.
    Type: Application
    Filed: December 18, 2007
    Publication date: June 19, 2008
    Inventors: Pravin Iyer, Clara Jeou Jen Lin, Stephen M. Lynch, Matthew C. Lucas, Ann Marie Madera, Kerem Erol Ozboya, Robert James Weikert, Ryan Craig Schoenfeld
  • Patent number: 7307082
    Abstract: This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I wherein X1 is (CH2)n or CO, n is 0 to 2 and R1, R2, R3 and R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: December 11, 2007
    Assignee: Roche Palo Alto LLC
    Inventors: Counde O'Yang, Ryan Craig Schoenfeld
  • Publication number: 20070281920
    Abstract: Compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ar, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, methods of preparing the compounds, and method of using the compounds for treatment of monoamine reuptake inhibitor-mediated diseases.
    Type: Application
    Filed: May 31, 2007
    Publication date: December 6, 2007
    Inventors: Ryan Craig Schoenfeld, Robert James Weikert
  • Publication number: 20040224964
    Abstract: This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I wherein X1 is (CH2)n or CO, n is 0 to 2 and R1, R2, R3 and R4 are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts thereof. The invention further relates to processes for preparing such compounds, to pharmaceutical compositions containing such compounds, and to methods for their use as therapeutic agents.
    Type: Application
    Filed: May 4, 2004
    Publication date: November 11, 2004
    Applicant: Roche Palo Alto LLC
    Inventors: Counde O'Yang, Ryan Craig Schoenfeld
  • Patent number: 6633923
    Abstract: A computer implemented method of creating and managing one or more interceptors. The method comprises the steps of intrinsically chaining the interceptors, and storing state information, in at least one of the chained interceptors, directed to a reference to the next interceptor. A server computer in a client-server environment that includes a processor configured to generate one or more interceptors and to intriscally chain the interceptors, and a memory associated with at least one of the chained interceptors and configured to store state information directed to a reference to the next interceptor thereof.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: October 14, 2003
    Assignee: IONA Technologies Inc.
    Inventors: Robert A Kukura, Ryan Craig, Matthew A Mihic