Abstract: An apparatus, system and related methods for controlling a pressurized flow from a high or low pressure system. An actuated sand dump system and related methods include a first valve positioned downstream of a high or low pressure system, a second valve positioned downstream of the first valve, a choke positioned between in the first and second valves, a plurality of pressure gauges, and a control unit operable to automatically open and close the first and second valves and the choke in a predetermined sequence, upon initiating the predetermined sequence, and in response to pressure measurements from the plurality of pressure gauges.

Abstract: A system, method, and computer-program product includes obtaining application configuration data; computing, via an execution of a designed experiment, a plurality of application usability tests based on the application configuration data; generating a computer-executable application based at least on the plurality of application usability tests; and deploying the computer-executable application to a target computing environment for execution by one or more users.

Abstract: A computing device receives a request requesting a screening design for an experiment. The device obtains factors for screening. A first factor has a first set of candidate inputs comprising at least two candidate inputs for allowable inputs in the experiment. A second factor has a second set of candidate inputs comprising at least three candidate inputs for allowable inputs in the experiment. The device receives an indication of a run size. The device generates the screening design by assigning, based on the run size, the first factor to a two-level group that only allows at most two allowable inputs for the first factor in the experiment. The device generates the screening design by assigning, based on the initial run size, the second factor to a three-level group that only allows at most three allowable inputs for the second factor in the experiment. The device outputs the screening design.

Abstract: A computing device obtains first and second factors for a nesting design and first and second sets of candidate options for the first and second factors, respectively. The computing device also receives a nesting indication that the second factor is nested within the first factor. The computing device generates the nesting design by portioning the first and second sets of candidate options into respective first and second different sets of groups. Based on the nesting indication, the computing device generates an assignment of groups for a design, and also selects options in the nesting design for the first and second factors based on the assignment of groups. The computing device also generates terms for a computer model for a computer simulation of the nesting design, as well as one or more computer-generated assessments of the nesting design based on the computer simulation.

Abstract: Provided herein are methods, compositions and articles of manufacture for use in connection with cell therapy involving the administration of one or more doses of a therapeutic T cell composition. The cells of the T cell composition express recombinant receptors such as chimeric receptors, e.g. chimeric antigen receptors (CARs) or other transgenic receptors such as T cell receptors (TCRs). Features of the provided embodiments, including the numbers of cells or units of cells administered and/or the potency of administered cells, provide various advantages, such as lower risk of toxicity in subjects administered the T cell compositions.

Abstract: Autonomous vehicle methods and systems are described herein for communicating with an autonomous or semi-autonomous vehicle to remotely control operation of the vehicle, to detect and remove unauthorized passengers, to deliver loads, to receive registration information for the vehicle, to provide accessibility information to the vehicle, and/or to receive sensor or other environmental data to integrate with an electronic game or other extended reality experience.

Abstract: A computing device receives a request requesting a screening design for an experiment. The device obtains, for the screening design, factors for screening in the experiment. A first factor is a categorical factor with a first set of candidate inputs comprising at least three candidate inputs in the experiment. A second factor is a continuous factor with a second set of candidate inputs comprising candidate input options within range(s) for the second factor. The device receives an indication of a run size that is a user-requested quantity of runs for the screening design. The device generates the screening design based on the run size. The device outputs the screening design. The screening design comprises runs of a quantity based on the user-requested quantity of runs for the screening design. The runs comprise the first set of candidate inputs and at least three inputs of the second set of candidate inputs.

Abstract: Methods, apparatuses, and testing devices comprising a fluid management layer including a fluid management body, a sample port defined in the fluid management body, an assay strip encased in the fluid management body along a fluid path, a valve defined on the assay strip, and a first internal vent having a first vent inlet, a first vent outlet, and a first venting channel connecting the first vent inlet to the first vent outlet, wherein the first vent inlet is arranged at a first location in the fluid management body along the fluid path downstream of the valve, and the first vent outlet is at a second location in the fluid management body upstream of the valve.

Abstract: A system including an implant and a tool for inserting and expanding the medical implant and locking the implant in place is disclosed. The medical implant may include an expandable body defined by a superior endplate and an inferior endplate that are hingedly coupled and may be expanded and lordosed. The implant may include a wedge disposed between the superior and inferior endplates that is configured to slide across a channel on inferior endplate and along an inclined groove on superior endplate. In at least some embodiments, an expansion screw is operative coupled to the threaded portion of the wedge that when expansion screw is rotated, the wedge is translated thereby expanding the implant.

Abstract: A solar module mounting bracket including a rail, having a box section configuration to support a solar module and a pair of arms each having a first end portion movably coupled to the rail. The pair of arms are movable relative to the rail between a first parallel configuration, and a second substantially configuration, in which the pair of arms define an opening configured to receive a torque tube. The arms each have a hole formed in a second end portion opposite the first end portion to receive a fastener to secure the rail to the torque tube.

Abstract: An electrochemically active structure having a core and a shell at least partially surrounding the core. Also a method of making the electrochemically active structure as described herein as well as electrochemical cells comprising the electrochemically active structure as described herein.

Abstract: Systems for manufacturing semiconductors are essential to enabling modern technologies. Such systems may include a central controller, a plurality of fluid supplies, a plurality of apparatus for controlling flow, and a processing chamber. The central controller may have a processor, a memory, and a communication module. The plurality of apparatus for controlling flow may have a device controller having an active component, a sensor, and a communication module. The communication may have a communication module, a memory, a sensor drive circuit operably coupled to the sensor, and an active component drive operably coupled to the active component. The central controller is configured to receive sensor data from the sensors of the plurality of apparatus for controlling flow and transmit active component commands to the active component drives of the device controllers to control the plurality of apparatus for controlling flow.

Abstract: Autonomous vehicle methods and systems are described herein for communicating with an autonomous or semi-autonomous vehicle to remotely control operation of the vehicle, to detect and remove unauthorized passengers, to deliver loads, to receive registration information for the vehicle, to provide accessibility information to the vehicle, and/or to receive sensor or other environmental data to integrate with an electronic game or other extended reality experience.

Abstract: An apparatus, system and related methods for controlling a pressurized flow from a high or low pressure system. An actuated sand dump system and related methods include a first valve positioned downstream of a high or low pressure system, a second valve positioned downstream of the first valve, a choke positioned between in the first and second valves, a plurality of pressure gauges, and a control unit operable to automatically open and close the first and second valves and the choke in a predetermined sequence, upon initiating the predetermined sequence, and in response to pressure measurements from the plurality of pressure gauges.

Abstract: Systems and methods are described for generating transactions based upon rideshare data and updating a distributed ledger. The method may include (1) monitoring a distributed ledger for an indication of an accident, the indication of the accident identifying at least a user and a time period; (2) obtaining rideshare data from the distributed ledger, wherein the rideshare data: identifies one or more rideshare companies for which the user offered driving services during the time period; and (3) verifying, based upon the rideshare data, a controlling party, wherein the controlling party is one of the user or one of the one or more rideshare companies.

Abstract: Confining lateral traversal within a network. An authorization request identifies a credential, a protected first resource, and an identifier of a protected second resource for which authorization is requested. A lateral traversal policy associated with the second resource is identified, which constrains access to the second resource to only resources that belong to a subset of resources including the second resource. When it is determined that the credential is configured for access to the second resource, and when it is determined that the first resource belongs to the subset of resources including the second resource, an authorization token is issued, which authorizes the credential to access the second resource via the first resource. Alternatively, when it is determined that the credential is granted access to the second resource, and when it is determined that the first resource is outside of the particular subset of resources, the authorization request is denied.

Abstract: Autonomous vehicle methods and systems are described herein for communicating with an autonomous or semi-autonomous vehicle to remotely control operation of the vehicle, to detect and remove unauthorized passengers, to deliver loads, to receive registration information for the vehicle, to provide accessibility information to the vehicle, and/or to receive sensor or other environmental data to integrate with an electronic game or other extended reality experience.

Abstract: A dual balance electrode trap having an outer chamber, a droplet dispenser holder removably coupled to the top surface of the outer chamber, and a rod holder having a central opening and four peripheral openings that are sized and shaped to allow four respective quadrupole metal rods to pass therethrough. The droplet dispenser holder has a top surface, a bottom surface, and a through hole that extends from the dispenser holder top surface to the droplet dispenser bottom surface. The through hole has a larger diameter portion adjacent to the top surface and a smaller diameter portion adjacent to the bottom surface, thereby preventing a droplet dispenser distal tip from extending entirely through the hole and contacting electrodes in the DBET. The rod holder is configured to be removably coupled to the quadrupole metal rods so that a location of the rod holder relative to the metal rods is adjustable.

Abstract: The present disclosure relates to optical devices and systems, specifically those related to light detection and ranging (LIDAR) systems. An example device includes a shaft defining a rotational axis. The shaft includes a first material having a first coefficient of thermal expansion. The device also includes a rotatable mirror disposed about the shaft. The rotatable mirror includes a multi-sided structure having an exterior surface and an interior surface. The multi-sided structure includes a second material having a second coefficient of thermal expansion. The second coefficient of thermal expansion is different from the first coefficient of thermal expansion. The multi-sided structure also includes a plurality of reflective surfaces disposed on the exterior surface of the multi-sided structure. The multi-sided structure yet further includes one or more support members coupled to the interior surface and the shaft.