Abstract: Techniques are provided for metadata management for enabling automated switchover in accordance with a configuration of storage solution that expresses a preference for either maintaining availability (e.g., a non-zero RPO mode) of the storage solution or avoiding data loss (e.g., a zero RPO mode). In one example, responsive to detecting a switchover trigger event, a node of a local cluster of a cross-site storage solution determines whether performance of an automated switchover from a failed cluster to a surviving cluster of the cross-site storage solution is enabled. Responsive to an affirmative determination, the node selectively proceeds with the automated switchover based on the configuration.

Abstract: The present disclosure is directed towards systems and methods built for predictively timing the inflation and/or deflation of an intra-aortic balloon pump. A controller operates in three states: (1) initialization state, (2) learning state, and (3) peak detection state. The controller decomposes a patient's electrocardiogram signal to a power signal. It then learns characteristics of the patient's electrocardiogram signal during the learning state and computes adaptive threshold parameter values. During the peak detection state, the controller applies the learnt threshold parameter values on a current electrocardiogram signal to identify occurrence and timings of R peaks in the electrocardiogram signal. The R-to-R peak timings are then used to trigger inflation of an intra-aortic balloon pump.

Abstract: A real time location system (RTLS) is provided for determining three-dimensional locations of nodes in an environment. The RTLS system includes at least one node associated with an asset in the environment. The at least one node has an unknown location. The system further includes at least one tracking device that communicates with the at least one node to obtain location data associated with the unknown location of the at least one node. A location module receives the location data associated with the unknown location of the at least one node and determines a real-time three-dimensional current location of the at least one node based on the location data. The real-time three-dimensional current location having x, y and z coordinates and the z coordinate indicates a height of the at least one node in the environment.

Abstract: Real time location systems are provided including one or more ultra-wideband (UWB) sensors positioned in an environment; one or more image capture sensors positioned in the environment; and at least one UWB tag associated with an object in the environment to provide a tagged item in the environment. The one or more UWB sensors and the one or more image capture sensors are integrated into at least one location device. The at one location device includes a UWB location device, a combination UWB/camera location device and/or a camera location device. A location of the tagged item is tracked using the at least one location device. and wherein a location of the tagged item is tracked using the at least one location device.

Abstract: One aspect of the subject matter described herein comprises a database management system. The database management system comprises a communication circuit, an interface, and a processor. The communication circuit receives information from databases via a communication network. The interface allows user operation and interaction via the communication network and the database management system. The processor provides data to and receives data from the interface, including a plurality of alphanumeric records comprising at least one unique identifier, obtains database records from other databases for each unique identifier, identifies a number of alphanumeric records in the plurality having events in their histories, determines a percentage of alphanumeric records in the plurality having negative events in their histories, generates a report including the determined percentages, and conveys the report to the user.

Abstract: The present invention provides a compound of Formula I: wherein R1 is H, halogen, C1-C3 alkyl, or C1-C3 alkoxy; R2 is H or halogen; and X is O, OCH2, or CH2, or a pharmaceutically acceptable salt thereof, wherein the compound of Formula I, or pharmaceutically acceptable salt thereof is useful for treating autoimmune and inflammatory diseases, such as atopic dermatitis, rheumatoid arthritis, and lupus nephritis.

Abstract: This disclosure describes a method for retrofitting an existing plant. The method includes adding a fractionation process to separate bran from other components in a feedstock to the existing plant, adding a pretreatment process downstream of the fractionation process, the pretreatment process configured to receive the bran and utilize water and heat to break down cellulose and hemicellulose in the bran; adding a hydrolysis and cellulosic fermentation process downstream of the pretreatment process and upstream of the fermentation process to hydrolyze the bran with a cellulase enzyme complex cocktail and to ferment with an organism to produce cellulosic beer; and combining the cellulosic beer with starch from the grain in the existing plant into the fermentation process to increase overall yield per feedstock unit in the existing plant.

Abstract: The present disclosure provides bifunctional compounds as HPK1 degraders via ubiquitin proteasome pathway, and method for treating diseases modulated by HPK1.

Abstract: Examples of the present disclosure may be directed to reducing a tension force or a compression force in one or more shafts of the delivery system. An elongate catheter may include the one or more shafts. The tension force or compression force may result from residual tension or compression in a shaft resulting from movement of the shaft. The tension force or compression force may alternatively or in combination result from interacting forces across a plurality of the shafts. The tension force or compression force may hinder the operation of the delivery system and in instances may damage the delivery system. Systems, devices, and methods for reducing the tension force or compression force are disclosed herein.

Abstract: Methods and systems for providing a flow of fluid to an endoscope. An illustrative container and tube set arranged and configured to couple to an endoscope may comprise a first container configured to contain a fluid, a sealing member, a compression member, a first fluid supply tube including a first lumen in fluid communication with the sealing member and the first container, a branched connector positioned in line with first fluid supply tube and including a first fluid inlet, a first fluid outlet, and a second fluid outlet, a second container having a second fluid inlet in fluid communication with the second fluid outlet of the branched connector, a second fluid supply tube in fluid communication with the bottom portion of the second container, and a first gas supply tube in operative fluid communication with the second container.

Abstract: Techniques are provided for metadata management for enabling automated switchover. An initial quorum vote may be performed before a node executes an operation associated with metadata comprising operational information and switchover information. After the initial quorum vote is performed, the node executes the operation upon one or more mailbox storage devices. Once the operation has executed, a final quorum vote is performed. The final quorum vote and the initial quorum vote are compared to determine whether the operation is to be designated as successful or failed, and whether any additional actions are to be performed.

Abstract: A system includes a processor configured to determine a driver identity. The processor is also configured to receive a request for a change to a driving mode and responsive to the request, enable or deny the driving mode based on mode-correlation to one of a predefined set of permissible driving modes pre-associated with the driver identity.

Abstract: An indoor location is mapped into a grid comprising grid cells, each cell associated with items or objects detected as being present in the corresponding cell. The grid, grid cells, and linked items and/or objects are generated and updated using an Augmented Reality (AR) algorithm that maps a physical environment into cells and measures distances and directions within the environment relative to each cell. Walking paths (routes) to the items within the indoor location are generated using the grid information. As a user walks a path, the user's position within the indoor location is mapped and tracked to the cells and the path revised based on the user's actual position. A user device provides video via an AR application to track the user's position; a rendering of the position and path are superimposed within the video being viewed by the user on the user-operated device.

Abstract: A laundry dryer includes a cabinet, a user interface that is operably coupled to the cabinet, a motor that is disposed within the cabinet and communicatively coupled with the user interface, and a controller that is communicatively coupled with the user interface and the motor, respectively. The controller includes a memory storage that includes a plurality of night routines. The controller is configured with a selectable time point and is further configured to select at least one of the plurality of night routines at the selectable time point.

Abstract: Provided herein are scaffold biomaterials comprising a decellularised fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularised fungal tissue comprising a cellulose- or chitin-based 3-dimensional porous structure. Methods for preparing such scaffold biomaterials, as well as uses thereof as an implantable scaffold for supporting animal cell growth, for promoting tissue regeneration, for promoting angiogenesis, for a tissue replacement procedure, and/or as a structural implant for cosmetic surgery are also provided. Therapeutic treatment and/or cosmetic methods employing such scaffolds are additionally described.

Abstract: Methods of auto-calibrating antennas in a target environment are provided including obtaining a map and associated scale of the target environment; displaying the map to a user on a user display device; discovering a plurality of antennas present in the target environment; illustrating the discovered plurality of antennas on the map; repositioning at least some of the plurality antennas on the map; locking selected ones of plurality of antennas into a current position to provide a plurality of locked antennas, wherein the plurality of locked antennas is equal to zero or greater; and auto-calibrating a remaining plurality of unlocked antennas, wherein auto-calibrating includes moving each of the remaining plurality of unlocked antennas from a first position to a second position.

Abstract: A modular humidifier system includes a base module having a frame and a wet-pack assembly, the wet-pack assembly being enclosed in the frame. The humidifier system also includes a fan module structured to draw air through the base module and a cover assembly structured to couple to each of the fan module and the base module. The frame includes a first side and a second side, where the fan module is structured to selectively couple to either the first side or the second side.

Abstract: A refrigerating appliance includes a cabinet having an inner liner that defines at least one aperture for accessing a refrigerating compartment. A door is operably coupled to the cabinet and is operable between open and closed positions. A plurality of storage surfaces is positioned within the refrigerating compartment. Each storage surface is adapted to receive at least one temporarily stored item. A scanning apparatus is adapted to record data related to the storage surfaces and the at least one temporarily stored item. The scanning apparatus conducts first and second data capturing phases. The secondary data recorded during the second data capturing phase is compared against previous data recorded during the first data capturing phase to create a current inventory manifest. The current inventory manifest is compared with a set of predetermined parameters related to the at least one temporarily stored item to selectively provide an output.

Abstract: Techniques for data analysis and user guidance are provided. One or more current measurements of one or more current analyte levels for the user are received from a sensor. A pattern is generated based on the one or more current measurements and the one or more past measurements. A first alignment with a first user target is then determined based on the pattern, where the first user target relates to one or more of a mental state or physical state of the user. A first result is output to the user, based on the determined first alignment.

Abstract: A three dimensional representation of sports data from multiple sources, which has A) a computer program stored on a non-transitory computer readable medium, B) a server operatively associated with the non-transitory computer readable medium, C) a computer vision model using feature detection algorithms, D) a database associated to the computer vision model, E) data to upload to the database, F) a graphical user interface to show data, and G) a computer device, whereby users access to the graphical user interface to upload and visualize the data. The data is visually shown through two-dimension and three-dimension images, text, numbers, animations, and custom visuals to allow the users to analyze the data.