Patents by Inventor Ryoji Kikumoto

Ryoji Kikumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutically active (omega-aminoalkoxy)bibenzyls
    Patent number: 4220603
    Abstract: (Omega-aminoalkoxy)bibenzyls are prepared and found useful as pharmaceutical agents, particularly as inhibitors of platelet aggregation.
    Type: Grant
    Filed: September 19, 1978
    Date of Patent: September 2, 1980
    Assignee: Mitsubishi Chemical Industries, Limited
    Inventors: Ryoji Kikumoto, Kunihiro Ninomiya, Harukazu Fukami, Hiroto Hara
  • Pharmaceutically active 2-(4-aminobutoxy)stilbenes
    Patent number: 4217366
    Abstract: 2-(4-aminobutoxy)stilbenes are prepared and found useful as pharmaceutical agents, particularly as anticonvulsants and skeletal muscle relaxants.
    Type: Grant
    Filed: February 14, 1979
    Date of Patent: August 12, 1980
    Assignee: Mitsubishi Chemical Industries, Ltd.
    Inventors: Ryoji Kikumoto, Akihiro Tobe, Harukazu Fukami, Kunihiro Ninomiya, Mitsuo Egawa
  • N.sup.2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4201863
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: August 31, 1978
    Date of Patent: May 6, 1980
    Assignees: Mitsubishi Chemical Industries, Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4173630
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: May 4, 1978
    Date of Patent: November 6, 1979
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -Naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof
    Patent number: 4168307
    Abstract: N.sup.2 -naphthalenesulfonyl-L-arginine amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid wherein R.sub.1 is alkenyl of not more than 10 carbon atoms, or substituted alkyl containing not more than 20 carbon atoms wherein said substituent is a member selected from the class consisting of alkoxy, alkoxycarbonyl, arylcarbamoyl acyl, acyloxy, N,N-polymethylenecarbamoyl and carboxy, and R.sub.2 is aryl, cycloalkyl, aralkyl or cycloalkylalkyl, respectively containing not more than 15 carbon atoms and R' is 1-naphthyl substituted with a member selected from the class consisting of 2-dialkylamino, 3-dialkylamino, 4-dialkylamino, 6-dialkylamino, 7-dialkylamino, 8-dialkylamino, respectively containing not more than 20 carbon atoms, and 5-dialkylamino containing 3-20 carbon atoms; or 2-naphthyl substituted with dialkylamino containing not more than 20 carbon atoms.
    Type: Grant
    Filed: October 21, 1977
    Date of Patent: September 18, 1979
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Yoshikuno Tamao, Kazuo Ohkubo, Shinji Tonomura
  • N.sup.2 -Naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof
    Patent number: 4154828
    Abstract: N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: October 21, 1977
    Date of Patent: May 15, 1979
    Assignees: Mitsubishi Chemical Industries, Ltd., Shosuke 0KAMOTO
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Yoshikuno Tamao, Kazuo Ohkubo, Shinji Tonomura
  • N.sup.2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4140681
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: June 7, 1977
    Date of Patent: February 20, 1979
    Assignee: Mitsubishi Chemical Industries, Limited
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -Substituted-L-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof
    Patent number: 4133880
    Abstract: N.sup.2 -substituted-L-arginine esters and amides, and the pharmaceutically acceptable acid addition salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: July 28, 1977
    Date of Patent: January 9, 1979
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4131673
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: June 7, 1977
    Date of Patent: December 26, 1978
    Assignees: Mitsubishi Chemical Industries, Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -naphthalenesulfonyl-L-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof
    Patent number: 4125619
    Abstract: N.sup.2 -naphthalenesulfonyl-L-arginine esters and amides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: November 14, 1978
    Assignees: Mitsubishi Chemical Industries, Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N2-Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4125604
    Abstract: N.sup.2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: June 7, 1977
    Date of Patent: November 14, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4117127
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: October 21, 1977
    Date of Patent: September 26, 1978
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4108986
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: August 22, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuno Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof, and antithrombotic compositions and methods employing them
    Patent number: 4104392
    Abstract: N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: September 30, 1976
    Date of Patent: August 1, 1978
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -arylsulfonyl-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4101653
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: July 18, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • Pharmaceutically active 2-omega-aminoalkoxydiphenylmethylmethanes
    Patent number: 4100299
    Abstract: 2-Omega-aminoalkoxydiphenylmethylmethanes have been found useful for palliating conditions of depression in warm blooded animals.
    Type: Grant
    Filed: June 1, 1977
    Date of Patent: July 11, 1978
    Assignee: Mitsubishi Chemical Industries Limited
    Inventors: Ryoji Kikumoto, Akihiro Tobe, Shinji Tonomura, Hidenobu Ikoma
  • N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4097591
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: March 10, 1977
    Date of Patent: June 27, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -arylsulfonyl-l-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4097472
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: June 27, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuno Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • N.sup.2 -naphthalenesulfonyl-L-argininamides, and pharmaceutical salts, compositions and methods
    Patent number: 4096255
    Abstract: N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: September 14, 1976
    Date of Patent: June 20, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Shosuke Okamoto, Akiko Hijikata
  • N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4093712
    Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
    Type: Grant
    Filed: January 19, 1977
    Date of Patent: June 6, 1978
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuno Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura