Patents by Inventor Ryoji Kikumoto

Ryoji Kikumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutically active 2-omega-aminoalkoxydiphenyl ethers
    Patent number: 4061776
    Abstract: This invention relates to 2-omega-aminoalkoxydiphenylethers and derivatives thereof which are pharmocologically active as antidepressants.
    Type: Grant
    Filed: November 18, 1976
    Date of Patent: December 6, 1977
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Ryoji Kikumoto, Akihiro Tobe, Hidenobu Ikoma
  • Pharmaceutically active 2-omega-aminoalkoxydiphenyl sulfides
    Patent number: 4060612
    Abstract: 2-Omega-aminoalkoxydiphenyl sulfides are prepared and found useful as pharmaceutical agents, particularly as antidepressants.
    Type: Grant
    Filed: July 12, 1976
    Date of Patent: November 29, 1977
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Ryoji Kikumoto, Akihiro Tobe, Shinji Tonomura, Hidenobu Ikoma
  • Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes
    Patent number: 4060641
    Abstract: 2-(3-Alkylaminopropoxy) diphenylmethanes have been produced and have been found to possess antidepressant activity.
    Type: Grant
    Filed: October 21, 1976
    Date of Patent: November 29, 1977
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Ryoji Kikumoto, Akihiro Tobe, Shinji Tonomura, Hidenobu Ikoma
  • N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4055636
    Abstract: N.sup.2 -alkoxynaphthalenesulfonyl-L-arginiamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis, and are prepared by reacting N.sup.2 -alkoxynaphthalenesulfonyl-L-arginyl halide with a secondary amine.
    Type: Grant
    Filed: December 9, 1975
    Date of Patent: October 25, 1977
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4055651
    Abstract: N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: January 28, 1976
    Date of Patent: October 25, 1977
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N.sup.2 -naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof
    Patent number: 4049645
    Abstract: N.sup.2 -naphthalenesulfonyl-L-arginine esters and amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is wherein R.sub.1 and R.sub.2 are members selected from the class consisting of hydrogen, alkyl, aryl, alkenyl and cycloalkyl, respectively containing not more than 10 carbon atoms, and aralykyl and cycloalkylalkyl, respectively containing not more than 15 carbon atoms; and R' is a member selected from the class consisting of 5,6,7,8-tetrahydro-l-naphthyl, 5,6,7,8-tetrahydro-2-naphthyl, 1-naphthyl, 2-naphthyl, 1-naphthyl substituted with halogen, nitro, cyano, hydroxy, alkyl containing not more than 10 carbon atoms, and 2-naphthyl substituted with halogen, nitro, cyano, hydroxy, alkyl containing ot more than 10 carbon atoms.
    Type: Grant
    Filed: March 29, 1976
    Date of Patent: September 20, 1977
    Assignees: Mitsubishi Chemical Industries Limited, Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Shinji Tonomura, Yoshikuni Tamao, Tohru Tezuka, Akiko Hijikata
  • N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4046876
    Abstract: N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: February 10, 1976
    Date of Patent: September 6, 1977
    Assignee: Mitsubishi Chemical Industries Limited
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4041156
    Abstract: N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: August 9, 1977
    Assignee: Mitsubishi Chemical Industries Limited
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4036955
    Abstract: N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: July 22, 1976
    Date of Patent: July 19, 1977
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura
  • Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes
    Patent number: 4024282
    Abstract: 2-(3-Alkylaminopropoxy) diphenylmethanes have been produced and have been found to possess antidepressant activity.
    Type: Grant
    Filed: November 25, 1975
    Date of Patent: May 17, 1977
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Ryoji Kikumoto, Akihiro Tobe, Shinji Tonomura, Hidenobu Ikoma
  • N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4018915
    Abstract: N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis, and are prepared by reacting N.sup.2 -alkoxynaphthalenesulfonyl-L-arginyl halide with a secondary amine.
    Type: Grant
    Filed: January 5, 1976
    Date of Patent: April 19, 1977
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
    Patent number: 4018913
    Abstract: N.sup.2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.
    Type: Grant
    Filed: January 14, 1976
    Date of Patent: April 19, 1977
    Assignees: Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Yoshikuni Tamao, Akiko Hijikata
  • N.sup.2 -dansyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof
    Patent number: 3978045
    Abstract: N.sup.2 -dansyl-L-arginine esters and amides having the formula ##SPC1##Or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the group consisting of(1) alkoxy, alkenyloxy, alkynyloxy, and cycloalkoxy, respectively, containing not more than 10 carbon atoms, aralkyloxy of not more than 15 carbon atoms, tetrahydrofurfuryloxy, and alkoxy of not more than 10 carbon atoms substituted with an alkoxy group of not more than 10 carbon atoms, halogen or nitro; ##EQU1## wherein R.sub.1 and R.sub.
    Type: Grant
    Filed: August 13, 1974
    Date of Patent: August 31, 1976
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Shosuke Okamoto, Ryoji Kikumoto, Yoshikuni Tamao, Shinji Tonomura, Kazuo Ohkubo