Patents by Inventor Ryuji Ueno

Ryuji Ueno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating vascular hyperpermeable disease
    Publication number: 20060229346
    Abstract: The present invention provides a method for treating a vascular hyperpermeable disease (except macular edema), which method comprises administering to a patient in need thereof a vascular adhesion protein-1 (VAP-1) inhibitor in an amount sufficient to treat said patient for said disease. The agents are 2-acylamino thiazole compounds.
    Type: Application
    Filed: March 31, 2004
    Publication date: October 12, 2006
    Applicants: Sucampo AG, Astellas Pharma Inc.
    Inventors: Ryuji Ueno, Akira Nagashima, Takayuki Inoue, Mitsuru Ohkubo, Kousci Yoshihara
  • Method for treating ocular hypertension and glaucoma
    Publication number: 20060205725
    Abstract: Provided is a method for treating ocular hypertension and glaucoma with reduced side effects such as keratoconjunctive disorders and macular edema, which comprises administering an ophthalmic composition comprising latanoprost as an active ingredient thereof to a subject in need of said treatment, wherein the ophthalmic composition contains substantially no benzalkonium chloride.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 14, 2006
    Inventor: Ryuji Ueno
  • Method for treating central nervous system disorders
    Publication number: 20060194880
    Abstract: The present invention provides a method for treating a central nervous system disorder in a mammalian subject, which comprises administering an effective amount of a 11-deoxy-prostaglandin compound to a subject in need thereof. The invention also provide novel 11-deoxy-prostaglandin compound.
    Type: Application
    Filed: January 26, 2006
    Publication date: August 31, 2006
    Inventor: Ryuji Ueno
  • Method for treating ocular hypertension and glaucoma
    Patent number: 7074827
    Abstract: Provided is a method for treating ocular hypertension and glaucoma with reduced side effects such as keratoconjunctive disorders and macular edema, which comprises administering an ophthalmic composition comprising latanoprost as an active ingredient thereof to a subject in need of said treatment, wherein the ophthalmic composition contains substantially no benzalkonium chloride.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: July 11, 2006
    Assignee: Sucampo AG (USA) Inc.
    Inventor: Ryuji Ueno
  • Chloride channel opener
    Patent number: 7064148
    Abstract: Disclosed is a novel use of a prostaglandin compound as a chloride channel opener. According to the instant invention, chloride channels in a mammalian subject can be opened by a prostaglandin compound to facilitate chloride ion transportation.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: June 20, 2006
    Assignee: Sucampo AG
    Inventors: Ryuji Ueno, John Cuppoletti
  • Use of macrolide compounds for the treatment of dry eye
    Patent number: 7063857
    Abstract: The present invention provides an agent for treating a dry eye, which contains a macrolide compound such as FK506.
    Type: Grant
    Filed: April 26, 2000
    Date of Patent: June 20, 2006
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Chloride channel opener
    Publication number: 20060122411
    Abstract: Disclosed is a novel use of a prostaglandin compound as a chloride channel opener. According to the instant invention, chloride channels in a mammalian subject can be opened by a prostaglandin compound to facilitate chloride ion transportation.
    Type: Application
    Filed: January 18, 2006
    Publication date: June 8, 2006
    Inventors: Ryuji Ueno, John Cuppoletti
  • Composition for topical administration
    Patent number: 7033604
    Abstract: The present invention provides a composition for topical administration comprising an interleukin 2 inhibitor and an antimicrobial agent as active ingredients thereof, wherein said interleukin 2 inhibitor contains a tricyclo compound as shown by the general formula (I) or pharmaceutically acceptable salt thereof. The present invention further provides a method for treating inflammations and/or infections comprising topical administration of an effective amount of an interleukin 2 inhibitor and an antimicrobial agent to a subject in need of the treatment of inflammations and/or infections.
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: April 25, 2006
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Method for treating gastrointestinal disorder
    Publication number: 20060063830
    Abstract: The present invention relates to a method for the long term treatment of gastrointestinal disorders in a human subject, which comprises administering an effective amount of a halogenated prostaglandin compound and/or its tautomer to the subject. The method induces substantially no electrolyte shifting during the term of the treatment. The compound used in the present invention can improve quality of life in the human subjects with gastrointestinal disorders, are similarly effective in treating male and female human subjects, and also effective in a human subject aged even 65 years and older.
    Type: Application
    Filed: September 1, 2005
    Publication date: March 23, 2006
    Inventor: Ryuji Ueno
  • Composition for topical administration
    Publication number: 20060034892
    Abstract: The present invention provides a composition for topical administration comprising an interleukin 2 inhibitor and an antimicrobial agent as active ingredients thereof, wherein said interleukin 2 inhibitor contains a tricyclo compound as shown by the general formula (I) or pharmaceutically acceptable salt thereof. The present invention further provides a method for treating inflammations and/or infections comprising topical administration of an effective amount of an interleukin 2 inhibitor and an antimicrobial agent to a subject in need of the treatment of inflammations and/or infections.
    Type: Application
    Filed: October 27, 2005
    Publication date: February 16, 2006
    Applicant: Sucampo AG
    Inventor: Ryuji Ueno
  • Method for treating drug-induced constipation
    Patent number: 6982283
    Abstract: Provided is a method for treating drug-induced constipation comprising a step of administering an effective amount of a 15-keto-prostaglaindin compound to a subject suffering from drug-induced constipation or a subject having a strong possibility of suffering from it. According to the present invention, a strong antagonistic action against drug-induced constipation can be obtained without substantially losing the main effect of the drug.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: January 3, 2006
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Prostaglandin compounds for the treatment of obesity
    Publication number: 20050261373
    Abstract: Provided is a composition for treating obesity which comprises an effective amount of a prostaglandin compound, especially, a compound of formula (I).
    Type: Application
    Filed: October 22, 2003
    Publication date: November 24, 2005
    Inventor: Ryuji Ueno
  • Method for providing a cathartic effect
    Publication number: 20050261375
    Abstract: The present invention relates to a novel method for providing a cathartic effort to a patient in need of cathartic induction, which comprises administering to the patient a cathartic-inducing effective amount of halogenated bioactive lipid comprising the following patial structure (I): The method is useful for relieving or preventing constipation, and also for cleansing the gastrointestinal tract.
    Type: Application
    Filed: July 28, 2005
    Publication date: November 24, 2005
    Inventor: Ryuji Ueno
  • Pharmaceutical compositions comprising fk506 derivatives and their use for the treatment of allergic diseases
    Publication number: 20050239813
    Abstract: The invention provides ophthalmic compositions and methods treating the symptoms of ocular allergies. The principle active ingredient in these compositions and methods is macrolide compound, such as tacrolimus, ascomycin and rapamycin and their derivatives. Optimal concentrations and dosing regimens are provided.
    Type: Application
    Filed: August 8, 2003
    Publication date: October 27, 2005
    Applicant: Sucampo Pharmaceuticals Inc.
    Inventor: Ryuji Ueno
  • Method for providing a cathartic effect
    Patent number: 6956056
    Abstract: The present invention relates to a novel method for providing a cathartic effect to a patient in need of cathartic induction, which comprises administering to the patient a cathartic-inducing effective amount of halogenated bioactive lipid comprising the following partial structure (I): The method is useful for relieving or preventing constipation, and also for cleansing the gastrointestinal tract.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: October 18, 2005
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno
  • Anti-constipation composition
    Publication number: 20050222195
    Abstract: An object of the present invention is to provide an anti-constipation composition containing a halogenated-bi-cyclic compound as an active ingredient in a ratio of bi-cyclic/mono-cyclic structure of at least 1:1. The halogenated-bi-cyclic compound is represented by Formula (I): where X1 and X2 are preferably both fluorine atoms. The composition can be used to treat constipation without substantive side-effects, such as stomachache.
    Type: Application
    Filed: June 2, 2005
    Publication date: October 6, 2005
    Inventor: Ryuji Ueno
  • Ophthalmic solution
    Publication number: 20050222265
    Abstract: The present invention relates to an ophthalmic solution comprising a prostaglandin compound and viscosity-increasing compound. The ophthalmic solution of the invention is excellent in stability and can provide long lasting and increased effect when administrated topically to the eyes of a patient.
    Type: Application
    Filed: April 21, 2005
    Publication date: October 6, 2005
    Inventor: Ryuji Ueno
  • Method for treatment of external secretion disorders
    Publication number: 20050090556
    Abstract: Disclosed is a method for treatment of external secretion disorders, which comprises administering a fatty 5 acid derivative to a subject in need of said treatment. The method of the present invention is useful for treatment of at least one condition selected from hypolacrimation including disorder of basal tear secretion, dry-eye syndrome, hyposalivation and dry-mouth syndrome.
    Type: Application
    Filed: November 23, 2004
    Publication date: April 28, 2005
    Inventor: Ryuji Ueno
  • Use of fk506 and analogues for treating allergic diseases
    Publication number: 20050070468
    Abstract: The present invention provides, in the treatment of allergic diseases using an interleukin 2 inhibitor, particularly a macrolide compound such as FK506, a method of treating an allergic disease, which includes setting a leading period for pre-administration of an interleukin 2 inhibitor.
    Type: Application
    Filed: November 20, 2002
    Publication date: March 31, 2005
    Applicant: SUCAMPO AG
    Inventor: Ryuji Ueno
  • Use of macrolide compounds for the treatment of dry eye
    Patent number: 6872383
    Abstract: The present invention provides an agent for treating a dry eye, which contains a macrolide compound such as FK506.
    Type: Grant
    Filed: January 30, 2003
    Date of Patent: March 29, 2005
    Assignee: Sucampo AG
    Inventor: Ryuji Ueno