Abstract: Described herein are methods and compositions for treating a beta-thalassemia.

Abstract: Presented herein are techniques enable existing hardware input/output resources, such as the hardware queues (queue control registers), of a network interface card to be shared with different hosts (i.e., each queue mapped to many hosts) by logically segregating the hardware I/O resources using assignable interfaces each associated with a distinct Process Address Space Identifier (PASID). That is, different assignable interfaces are created and associated with different PASIDs, and these assignable interfaces each correspond to a different host (i.e., there is a mapping between a host, an assignable interface, a PASID, and a partition of a hardware queue). The result is that that the hosts can use the assignable interface to directly access the hardware queue partition that corresponds thereto.

Abstract: Synthetic nutritional compositions tailored for infants of specific ages comprising Lycopene in concentrations reflecting those found in human milk produced for infants of the same age, and nutritional systems comprising them.

Abstract: Pre-filled syringes, pharmaceutical compositions, and kits and methods relating to same allow for emergency administration of one or more drugs from prefilled glass syringes to a patient via a needleless connector. In preferred embodiments, the prefilled glass syringe has a drug volume of at least 5 mL, has a Luer-lock, and has a syringe tip with an internal channel that has a diameter of about 1.7 mm. Such syringes advantageously allow storage of emergency drugs without leaching of plastic materials and degradation, and substantially improve the safety profile where the syringe is attached to an IV line via a needleless connector.

Abstract: One or more computing devices, systems, and/or methods for video encoding are provided. For example, a video file may be segmented into at least a first portion and a second portion. The first portion may be analyzed to determine that the first portion is associated with a first level of complexity, and the second portion may be analyzed to determine that the second portion is associated with a second level of complexity. A first bitrate associated with the first level of complexity may be determined, and a second bitrate associated with the second level of complexity may be determined. The first portion may be encoded at the first bitrate to generate a first encoded portion, and the second portion may be encoded at the second bitrate to generate a second encoded portion. The first encoded portion and the second encoded portion may be assembled to generate an optimized video file.

Abstract: A manipulator arm for moving a load from a first position at a first elevation, to a second position at a second elevation, provides a base and defines plural spaced apart axle holes. A fulcrum lever link formed of a channel beam defines plural spaced apart axle holes. A first load member, and two support members extend between, and pivotally interconnect, the base plate and the fulcrum lever link and define a quadrilateral lift frame about the pivotal interconnections. An actuator operatively communicates between the first load member and the fulcrum lever link and the fulcrum lever link provides mechanical advantage to the actuator to cause the quadrilateral lift frame to change from a first configuration at the first position to a second configuration at the second position.

Abstract: A fastener assembly is provided having a cylindrical shank with a plurality of annular grooves formed along a length of the shank. A plurality of elongated ribs extends perpendicular to the grooves along the length. A fastener disc is provided with a central opening with a diameter less than a cylindrical shank diameter wherein an inner edge of the central opening includes a contact surface. The fastener disc is retained on the fastener portion in a locked position when the contact surface engages one of the plurality of grooves with a friction fit. The fastener disc is rotated to a release position so that the elongated rib contacts the inner edge thereby releasing the contact surface from the grooves.

Abstract: A computer-readable medium, computer-implemented method, and system are provided. In one embodiment, a compensation pattern is defined for a step of an executable process, and the step of the executable process is executed. A change request is received, and, based on the change request, the compensation pattern is applied to the step of the executable process.

Abstract: The invention relates to a method of synthesizing liposomes and liposomal spherical nucleic acids with hydrophobic molecules functionalized to the surface. The lipid particles contain one or more agents that elicit an immune response.

Abstract: A supported oxidative coupling of methane (OCM) catalyst comprising a support and an OCM catalytic composition characterized by the general formula AaZbEcDdOx; wherein A is an alkaline earth metal; wherein Z is a first rare earth element; wherein E is a second rare earth element; wherein D is a redox agent or a third rare earth element; wherein the first rare earth element, the second rare earth element, and the third rare earth element, when present, are not the same; wherein a is 1.0; wherein b is from about 0.1 to about 10.0; wherein c is from about 0.1 to about 10.0; wherein d is from about 0 to about 10.0; and wherein x balances the oxidation states.

Abstract: A node includes a plurality of ports configured to provide a service over a primary Multi-Segment Pseudowire (MS-PW) and a backup MS-PW in a network; a switching fabric interconnecting the plurality of ports; and a controller communicatively coupled to the plurality of ports and the switching fabric, wherein the controller is configured to receive a pseudowire status message for each of the primary MS-PW and the backup MS-PW, determine a Signal Degrade condition on one of the primary MS-PW and the backup MS-PW based on the pseudowire status message, and cause a switch of the service to an inactive one of the primary MS-PW and the backup MS-PW based on a Signal Degrade condition on an active one of the primary MS-PW and the backup MS-PW. The controller can further provide a trap to a management system based on the determined Signal Degrade condition.

Abstract: Disclosed herein is a multiplexed design with three-dimensional plasmonic nanofocusing and confinement of light, demonstration of reproducible and robust single-molecule optical fingerprints using two complementary vibrational spectroscopy techniques (infrared and Raman spectroscopy), identification of respective vibrational modes which uniquely fingerprint the biomolecular species, and facile differentiation of respective fingerprints in DNA mixtures, as well as epigenetic modifications. While the nanometer scale mode volumes still prevent single letter identification of DNA sequence, we show an alternative method for identifying A, T, G, C DNA nucleotides in “k-mers” using sequences of these blocks as a unique and high-throughput alternative to single letter sequences (similar to binary and hexadecimal systems). Furthermore, additivity shown in single-molecule DNA mixtures and robust optical signatures can also be used in a raster-type step scan to identify single letter sequences.

Abstract: An example method includes detecting, using sensors, packets throughout a datacenter. The sensors can then send packet logs to various collectors which can then identify and summarize data flows in the datacenter. The collectors can then send flow logs to an analytics module which can identify the status of the datacenter and detect an attack.

Abstract: When the speed of head movement exceeds the processing capability of the system, a reduced depiction is displayed. As one example, the resolution may be reduced using coarse pixel shading in order to create a new depiction at the speed of head movement. In accordance with another embodiment, only the region the user is looking at is processed in full resolution and the remainder of the depiction is processed at lower resolution. In still another embodiment, the background depictions may be blurred or grayed out to reduce processing time.

Abstract: In one example, at least one peripheral interconnect switch obtains, from a first endpoint device, a message initiating a direct memory access data transfer between the first endpoint device and a second endpoint device. The message indicates an address assigned to the second endpoint device by a host device as a destination of the message. Based on the address assigned to the second endpoint device by the host device, the at least one peripheral interconnect switch identifies an address assigned to the second endpoint device by the at least one peripheral interconnect switch. In response to identifying the address assigned to the second endpoint device by the at least one peripheral interconnect switch, the at least one peripheral interconnect switch provides the message to the second endpoint device.

Abstract: Described herein is an apparatus and a corresponding method for performing warehouse zoning and further monitoring the zoned warehouse. The apparatus includes circuitry that partitions a workspace into a plurality of zones based on an area of the workspace, and a number of transportation vehicles and a number of item racks that are to be deployed in the workspace. A location of each zone within the workspace is determined based on a location of a first type of station that is disposed outside the workspace. The apparatus determines for each zone, an area of the zone and receives a signal indicating occurrence of an event in one of the zones. Further, the apparatus determines a degree of criticality of the occurred event which indicates whether workspace operation in the zone can be continued, and initiates an operation at a timing that is based on the determined degree of criticality.

Abstract: An example method can include choosing a pattern or patterns of network traffic. This pattern can be representative of a certain type of traffic such as an attack. The pattern can be associated with various components of a network and can describe expected behavior of these various components. A system performing this method can then choose a nodes or nodes to generate traffic according to the pattern and send an instruction accordingly. After this synthetic traffic is generated, the system can compare the behavior of the components with the expected behavior. An alert can then be created to notify an administrator or otherwise remedy any problems.

Abstract: Use of a ternary vanadate of formula (I): Fex MeIy MeIIz VO4 wherein MeI and MeII are different from each other and each stand for an element selected from the group consisting of Y, La, Ce, Pr, Nd, Sm, Er, Gd, Tb, Dy, Ho, Tm, Yb, Lu, Al, Bi and Sb and wherein x=0.05-0.9; y=0.05-0.9; z=0.05-0.9; x+y+z=1, as a catalyst for the oxidation of carbonaceous compounds in combustion engines.

Abstract: A hydraulic motor brake for providing load holding torque to a hydraulic motor and comprising a housing, a plate fixedly mounted within the housing, a piston mounted for bi-directional translation relative to the plate along a longitudinal axis, and a plurality of friction-producing members arranged such that the piston and plate at least partially define a brake release chamber and the piston, normally biased in engagement with the friction-producing members to produce load holding torque, translates away from the plate and disengages from the friction-producing members to stop producing load holding torque in response to pressurized hydraulic fluid being received by the brake release chamber. The hydraulic motor brake further comprises a wear plate with the brake housing and wear plate defining bores arranged in coaxial alignment with threaded bores of the hydraulic motor for detachably attaching the hydraulic motor brake to the hydraulic motor as a self-contained unit.

Abstract: A pipeline is configured to access a memory that stores a texture block and metadata that encodes compression parameters of the texture block and a residency status of the texture block. A processor requests access to the metadata in conjunction with requesting data in the texture block to perform a shading operation. The pipeline selectively returns the data in the texture block to the processor depending on whether the metadata indicates that the texture block is resident in the memory. A cache can also be included to store a copy of the metadata that encodes the compression parameters of the texture block. The residency status and the metadata stored in the cache can be modified in response to requests to access the metadata stored in the cache.