Patents by Inventor Said Saim

Said Saim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122920
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 18, 2024
    Inventors: Said SAIM, Alison B. FLEMING, Ravi K. VARANASI
  • Publication number: 20230103975
    Abstract: An injector includes a push rod, a magazine tube, a gate, a cannula and an actuator. The magazine tube has a lumen extending from an inlet to an outlet thereof. The magazine tube slidingly receives at least one implant therein. The gate has a closed configuration in which it covers the outlet of the magazine tube and an open configuration in which it does not cover the outlet of the magazine tube. The cannula has a distal end configured to be inserted into an eye. A lumen of the cannula is in fluid communication with the lumen of the magazine tube when the gate is in the open configuration. Actuation of the actuator moves the gate from the closed configuration to the open configuration and causes translation of the pushrod through the magazine tube and the cannula.
    Type: Application
    Filed: October 3, 2022
    Publication date: April 6, 2023
    Inventors: Michelle HOWARD-SPARKS, Said SAIM, Amelia SCHILLING, Dario PAGGIARINO, Nathan ROLLINS, Evan Hunter WILLIAMS, Phillip HALBERT, Daniel P. SMITH, Michael W. METZ, Dustin GAIDOS, Joshua MARTIN
  • Publication number: 20220168142
    Abstract: This invention relates to implantable bioerodible inserts for delivering an active pharmaceutical ingredient to the eye. The invention also relates to methods of treatment using such inserts as well as methods of manufacturing such inserts.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Inventors: Said SAIM, Michelle SPARKS, Dario PAGGIARINO, Basel KARZOUN
  • Patent number: 10668060
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: June 2, 2020
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Roman V. Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 10646485
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: May 12, 2020
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20190262335
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: May 15, 2019
    Publication date: August 29, 2019
    Inventors: Roman V. Rariy, Alison FLEMING, Jane C. HIRSH, Said SAIM, Ravi K. VARANASI
  • Publication number: 20190255038
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: December 13, 2018
    Publication date: August 22, 2019
    Inventors: Said SAIM, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20190167662
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: June 25, 2018
    Publication date: June 6, 2019
    Inventors: Roman Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 10188644
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: January 29, 2019
    Assignee: COLLEGIUM PHARMACEUTICAL, INC
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20180369236
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 27, 2018
    Inventors: Roman V. Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Publication number: 20180289697
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: April 11, 2018
    Publication date: October 11, 2018
    Inventors: Said SAIM, Alison B Fleming, Ravi K. Varanasi
  • Patent number: 10004729
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: June 26, 2018
    Assignee: COLLEGIUM PHARMACEUTICAL, INC.
    Inventors: Roman V. Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Patent number: 9968598
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: May 15, 2018
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20170368057
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Application
    Filed: July 13, 2017
    Publication date: December 28, 2017
    Inventors: Said SAIM, Alison B. Fleming, Ravi K. Varanasi
  • Publication number: 20170319575
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: May 26, 2017
    Publication date: November 9, 2017
    Inventors: Roman V. Rariy, Alison FLEMING, Jane C. HIRSH, Said SAIM, Ravi K. VARANASI
  • Patent number: 9737530
    Abstract: The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to abuse, the process of curing such composition in order to improve the dissolution stability, method of using the same for treatment of pain.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: August 22, 2017
    Assignee: COLLEGIUM PHARMACEUTICAL, INC.
    Inventors: Said Saim, Alison B. Fleming, Ravi K. Varanasi
  • Patent number: 9682075
    Abstract: Tamper-resistance pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: June 20, 2017
    Assignee: COLLEGIUM PHARMACEUTICAL, INC.
    Inventors: Roman Rariy, Alison Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi
  • Publication number: 20150004244
    Abstract: Tamper-resistance pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: June 30, 2014
    Publication date: January 1, 2015
    Inventors: Roman RARIY, Alison Fleming, Jane C. Hirsh, Said SAIM, Ravi K. Varanasi
  • Publication number: 20150005332
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Application
    Filed: July 1, 2014
    Publication date: January 1, 2015
    Inventors: Roman RARIY, Alison FLEMING, Jane C. HIRSH, Said SAIM, Ravi K. VARANASI
  • Patent number: 8840928
    Abstract: Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opioids. The tamper-resistant compositions retard the release of drug, even if the physical integrity of the formulation is compromised (for example, by chopping with a blade or crushing) and the resulting material is placed in water, snorted, or swallowed. However, when administered as directed, the drug is slowly released from the composition as the composition is passes through the GI tract.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: September 23, 2014
    Assignee: Collegium Pharmaceutical, Inc.
    Inventors: Roman V. Rariy, Alison B. Fleming, Jane C. Hirsh, Said Saim, Ravi K. Varanasi