Patents by Inventor Saleem Ahmad

Saleem Ahmad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dihydropyridinone MGAT2 inhibitors
    Patent number: 9822074
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: November 21, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Saleem Ahmad, Lidet A. Negash
  • Indole carboxamide compounds
    Patent number: 9802915
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: October 31, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Qingjie Liu, Scott Hunter Watterson, Saleem Ahmad, Andrew J. Tebben
  • DIHYDROPYRIDINONE MGAT2 INHIBITORS
    Publication number: 20170283381
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: June 9, 2017
    Publication date: October 5, 2017
    Inventors: Saleem Ahmad, Lidet A. Negash
  • INDOLE CARBOXAMIDE COMPOUNDS
    Publication number: 20170260160
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 14, 2017
    Inventors: Qingjie Liu, Scott Hunter Watterson, Douglas G. Batt, Saleem Ahmad, Myra Beaudoin Bertrand, Hua Gong, Weiwei Guo, John E. Macor, Khehyong Ngu, Andrew J. Tebben, Joseph A. Tino
  • TETRAZOLONE-SUBSTITUTED DIHYDROPYRIDINONE MGAT2 INHIBITORS
    Publication number: 20170260159
    Abstract: The present invention provides compounds of Formula (I): a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, a solvate thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 14, 2017
    Inventor: Saleem Ahmad
  • ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS
    Publication number: 20170216263
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: April 17, 2017
    Publication date: August 3, 2017
    Inventors: Huji Turdi, Jon J. Hangeland, R. Michael Lawrence, Dong Cheng, Saleem Ahmad, Wei Meng, Robert Paul Brigance, Pratik Devasthale, Guohua Zhao
  • Indole carboxamide compounds
    Patent number: 9688629
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: June 27, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Qingjie Liu, Scott Hunter Watterson, Saleem Ahmad
  • Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors
    Patent number: 9688656
    Abstract: The present invention provides compounds of Formula (I): a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, a solvate thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: June 27, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventor: Saleem Ahmad
  • Aryl dihydropyridinones and piperidinone MGAT2 inhibitors
    Patent number: 9663466
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: May 30, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Huji Turdi, Jon J. Hangeland, R. Michael Lawrence, Saleem Ahmad, Wei Meng, Robert Paul Brigance, Pratik Devasthale, Guohua Zhao
  • INDOLE CARBOXAMIDE COMPOUNDS
    Publication number: 20170066740
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Application
    Filed: November 17, 2016
    Publication date: March 9, 2017
    Inventors: Qingjie Liu, Scott Hunter Watterson, Saleem Ahmad, Andrew J. Tebben
  • Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
    Patent number: 9586900
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are melanin concentrating hormone receptor-1 (MCHR1) antagonists which may be used as medicaments.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: March 7, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Saleem Ahmad, Guohua Zhao, William N. Washburn
  • TETRAZOLONE-SUBSTITUTED DIHYDROPYRIDINONE MGAT2 INHIBITORS
    Publication number: 20170015648
    Abstract: The present invention provides compounds of Formula (I): a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, a solvate thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyl-transferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: March 5, 2015
    Publication date: January 19, 2017
    Inventor: Saleem Ahmad
  • Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
    Patent number: 9499482
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are melanin concentrating hormone receptor-1 (MCHR1) antagonists which may be used as medicaments.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: November 22, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: William N. Washburn, Murugaiah Andappan Murugaiah Subbaiah, Saleem Ahmad
  • DIHYDROPYRIDINONE MGAT2 INHIBITORS
    Publication number: 20160256445
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: May 13, 2016
    Publication date: September 8, 2016
    Inventors: Saleem Ahmad, Lidet A. Negash
  • Dihydropyridinone MGAT2 inhibitors
    Patent number: 9365558
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: June 14, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Saleem Ahmad, Lidet A. Negash
  • INDOLE CARBOXAMIDE COMPOUNDS
    Publication number: 20160115126
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Application
    Filed: October 23, 2015
    Publication date: April 28, 2016
    Inventors: Qingjie Liu, Scott Hunter Watterson, Douglas G. Batt, Saleem Ahmad, Myra Beaudoin Bertrand, Hua Gong, Weiwei Guo, John E. Macor, Khehyong Ngu, Andrew J. Tebben, Joseph A. Tino
  • ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS
    Publication number: 20160031816
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: October 14, 2015
    Publication date: February 4, 2016
    Inventors: Huji Turdi, Jon J. Hangeland, R. Michael Lawrence, Dong Cheng, Saleem Ahmad, Wei Meng, Robert Paul Brigance, Pratik Devasthale, Guohua Zhao
  • Aryl dihydropyridinones and piperidinone MGAT2 inhibitors
    Patent number: 9187424
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: November 17, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Huji Turdi, Jon J. Hangeland, R. Michael Lawrence, Dong Cheng, Saleem Ahmad, Wei Meng, Robert Paul Brigance, Pratik Devasthale, Guohua Zhao
  • ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS
    Publication number: 20150315144
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
    Type: Application
    Filed: June 16, 2014
    Publication date: November 5, 2015
    Inventors: Huji Turdi, Jon J. Hangeland, R. Michael Lawrence, Dong Cheng, Saleem Ahmad, Wei Meng, Robert Paul Brigance, Pratik Devasthale, Guohua Zhao
  • PYRROLONE OR PYRROLIDINONE MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS
    Publication number: 20150218093
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are melanin concentrating hormone receptor-1 (MCHR1) antagonists which may be used as medicaments.
    Type: Application
    Filed: September 3, 2013
    Publication date: August 6, 2015
    Applicant: Bristol-Myers Squibb Company
    Inventors: Saleem Ahmad, Guohua Zhao, William N. Washburn